Cochrane · systematic review · CD013390

Surgical interventions for infantile nystagmus syndrome

Cham, KM, Abel, LA, Busija, L, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library

Eyes and VisionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
4
No studies
3
Included studies
NR
No studies 3 · 42.9%Ungraded 0 · 0%Very low 4 · 57.1%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Summary of Findings Table ‐ Large retro‐equatorial recession of horizontal rectus muscle of 9 mm on the medial rectus and 12 mm on the lateral rectus compared to simple tenotomy and resuturing of the 4 horizontal rectus muscles for the surgical treatment of INS

Population: infantile nystagmus syndrome
7 questions
OutcomeEffectEvidenceStatus / GRADE
Change in binocular best‐corrected distance visual acuity
Summary of Findings Table ‐ Large retro‐equatorial recession of horizontal rectus muscle of 9 mm on the medial rectus and 12 mm on the lateral rectus vs simple tenotomy and resuturing of the 4 horizontal rectus muscles
no estimate extracted1 study · 10 participantsVery low
Downgraded: risk of bias, imprecision
Change in head posture ‐ not reported
Summary of Findings Table ‐ Large retro‐equatorial recession of horizontal rectus muscle of 9 mm on the medial rectus and 12 mm on the lateral rectus vs simple tenotomy and resuturing of the 4 horizontal rectus muscles
no estimate extractedNRNo studies
Change in intensity of the nystagmus waveform
Summary of Findings Table ‐ Large retro‐equatorial recession of horizontal rectus muscle of 9 mm on the medial rectus and 12 mm on the lateral rectus vs simple tenotomy and resuturing of the 4 horizontal rectus muscles
no estimate extracted1 study · 10 participantsVery low
Downgraded: risk of bias, imprecision
Change in foveation period durations of the waveform ‐ not reported
Summary of Findings Table ‐ Large retro‐equatorial recession of horizontal rectus muscle of 9 mm on the medial rectus and 12 mm on the lateral rectus vs simple tenotomy and resuturing of the 4 horizontal rectus muscles
no estimate extractedNRNo studies
Change in visual recognition times ‐ not reported
Summary of Findings Table ‐ Large retro‐equatorial recession of horizontal rectus muscle of 9 mm on the medial rectus and 12 mm on the lateral rectus vs simple tenotomy and resuturing of the 4 horizontal rectus muscles
no estimate extractedNRNo studies
Change in proportion of participants with adverse effects with a probable causal link to the treatment
Summary of Findings Table ‐ Large retro‐equatorial recession of horizontal rectus muscle of 9 mm on the medial rectus and 12 mm on the lateral rectus vs simple tenotomy and resuturing of the 4 horizontal rectus muscles
no estimate extracted1 study · 10 participantsVery low
Downgraded: risk of bias, imprecision
Change in quality of life
Summary of Findings Table ‐ Large retro‐equatorial recession of horizontal rectus muscle of 9 mm on the medial rectus and 12 mm on the lateral rectus vs simple tenotomy and resuturing of the 4 horizontal rectus muscles
no estimate extracted1 study · 10 participantsVery low
Downgraded: risk of bias, imprecision