Cochrane · systematic review · CD011977
Blue‐light filtering intraocular lenses (IOLs) for protecting macular health
Downie, LE, Busija, L, Keller, PR · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library
Eyes and VisionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
4
No studies
3
Included studies
NR
No studies 3 · 42.9%Ungraded 0 · 0%Very low 3 · 42.9%Low 0 · 0%Moderate 1 · 14.3%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Blue‐light filtering intraocular lenses (IOL) compared to non blue‐light filtering IOL for protecting macular health
Population: adults undergoing cataract surgery with IOL implantation
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Change in distance BCVA, between baseline and 12 months Blue‐light filtering intraocular lenses (IOL) vs non blue‐light filtering IOL | no estimate extracted | 2 studies · 131 participants | Moderate Downgraded: risk of bias, imprecision |
Distance BCVA, considered as a dichotomous outcome (being the proportion of eyes that experienced loss of 15 or more letters from baseline BCVA), at six months Blue‐light filtering intraocular lenses (IOL) vs non blue‐light filtering IOL | no estimate extracted | 2 studies · 63 participants | Very low Downgraded: risk of bias, imprecision |
Contrast sensitivity function, measured in log Contrast Sensitivity at six months Blue‐light filtering intraocular lenses (IOL) vs non blue‐light filtering IOL | no estimate extracted | NR | No studies |
Colour discrimination, measured as the proportion of eyes that had a measurable loss from baseline using Farnsworth‐Munsell 100‐hue colour test score under photopic conditions at six months Blue‐light filtering intraocular lenses (IOL) vs non blue‐light filtering IOL | no estimate extracted | NR | No studies |
Proportion of participants with adverse events with a probable causal link with the study interventions at six months Blue‐light filtering intraocular lenses (IOL) vs non blue‐light filtering IOL | no estimate extracted | NR | No studies |
Proportion of eyes that developed late‐stage AMD, being CNV and/or GA, at three years of Blue‐light filtering intraocular lenses (IOL) vs non blue‐light filtering IOL | no estimate extracted | 1 study · 50 participants | Very low Downgraded: risk of bias, imprecision |
Proportion of eyes that developed any stage of AMD at 12 months Blue‐light filtering intraocular lenses (IOL) vs non blue‐light filtering IOL | no estimate extracted | 2 studies · 144 participants | Very low Downgraded: risk of bias, imprecision |