Search review questions

Aesthetics · Children and adults (with or without carious lesions) · 12 months, Children

Dental caries / early childhood caries (ECC) · Children (approx. 4-18 years) · Study design: cross-sectional

dmfs index score · For interventions, pregnant women, mothers or other caregivers of infants in the first year of life; for outcomes,… · Children assessed at 3 yrs

Prenatal vitamin D deficiency prevalence · Pregnant mothers · Pregnancy, Overall

Dental pain or sensitivity · Children and adults (with or without carious lesions)

Early childhood caries experience (mean dmft) · Children younger than 71 months (under 6 years) · Gini index: low inequality

Mother self-reported oral health behaviours · For interventions, pregnant women, mothers or other caregivers of infants in the first year of life; for outcomes,…

Pit-and-fissure caries progression (ICDAS), CO2 laser vs fluoride varnish alone · Rechmann 2013 (single RCT, n=20, 12-month follow-up)

Caries arrestment at the tooth level · Children and adults with active dental caries (aged 1-50; mostly preschool/school children with primary dentition) · 6 to 12 months, SDF vs NAF

Enamel remineralization extent · Human enamel specimens around orthodontic brackets (in vitro) · pH cycling / biofilm challenge 14 to 28 days, Overall

Dental caries in children · Infants and children (aged about 2 to 8 years) whose mothers' vitamin D status was assessed during pregnancy · Maternal 25(OH)D measured at gestational weeks 6 to 38, Gestational-age subgroup: weeks 6 to 38

Overall success (composite of clinical and radiographic success) · Permanent teeth with carious pulp exposure · >=12 months, Hemostasis <=6 min

Fluorosis (percentage prevalence in permanent teeth) · Children exposed to topical fluoride when under 6 years old; fluorosis assessed in permanent teeth at 6 to 18 years · Fluorosis assessed when most permanent teeth of interest had erupted (6 to 18 years)

Child dental attendance · For interventions, pregnant women, mothers or other caregivers of infants in the first year of life; for outcomes,… · Birth to 6 yrs

Secondary prevention of caries · Children and adults (with or without carious lesions)

Early childhood caries (ECC) · Children aged ≤6 years (early childhood) · Exposure and outcome assessed concurrently (observational); children aged ≤6 years, Sample collection: dental plaque

Caries presence in primary teeth · For interventions, pregnant women, mothers or other caregivers of infants in the first year of life; for outcomes,… · Children assessed at 3-5 yrs

Early childhood caries experience (mean dmft) · Children younger than 71 months (under 6 years) · Region: Middle East

Early childhood caries (ECC) · Children aged <6 years · Study location: Asia

Enamel remineralization / anti-demineralization extent · Human enamel specimens around orthodontic brackets (in vitro) · pH cycling 14 days to 6 months (majority 14 days), Overall

Periodontal parameters (all measures pooled) in OC cases vs controls · Adults in case-control studies (oral cancer patients vs healthy controls) · Not specified, Overall (all periodontal measures pooled)

Streptococcus mutans salivary/plaque counts (cariogenic microbiota) · Children and adolescents aged 0-18 years with non-syndromic cleft lip and palate (CLP)

Child microbiological presence (any mutans streptococci colonisation) · For interventions, pregnant women and mothers of infants in the first year of life; for outcomes, children up to 6…

Prevention of new caries (caries development/increment) · Preschool children (primary dentition) at risk of new caries · 6 to 18 months

Child oral health behaviours · For interventions, pregnant women, mothers or other caregivers of infants in the first year of life; for outcomes,…

Early childhood caries (ECC) prevalence (%, dmft>0) · Children younger than 71 months (under 6 years) · Region: Europe

Fluorosis (percentage prevalence in permanent teeth) · Children exposed to topical fluoride when under 6 years old; fluorosis assessed in permanent teeth at 6 to 18 years · Fluorosis assessed when most permanent teeth of interest had erupted (6 to 18 years)

Dental caries · Children (<18 years) with vs without dental caries · Dominant model (TT+TC vs CC), Primary dentition

Overall success (composite of clinical and radiographic success) · Permanent teeth with carious pulp exposure · >=12 months, Hemostasis unknown

Spontaneous space closure · Children and adolescents after extraction of a mandibular permanent first molar (before eruption of the second molar) · Until eruption of the permanent second molar (median follow-up 4.0 years), Mandible

Dental caries · Children (<18 years) with vs without dental caries · Recessive model (TT vs TG+GG)

Dental caries · Children (<18 years) with vs without dental caries · Dominant model (TT+TC vs CC), PCR-RFLP genotyping

Spontaneous space closure · Children and adolescents (<18 years) after extraction of a permanent first molar before eruption of the permanent… · Until eruption of the permanent second molar (median follow-up 4.0 years), Maxilla

Adverse effects · Children and adults (with or without carious lesions) · 12 months, Children

Bacterial plaque index · Children and/or adolescents (<18 years) without background systemic disease · Probiotic presentation: milk (vs other presentations; p-interaction=0.01)

Adverse effects · Children and adults (with or without carious lesions) · 24 months, Children

Dental caries, prevalence · Primary school children in Ethiopia · Sampling technique: multi-stage random sampling

Dental caries · Children (<18 years) with vs without dental caries · Allelic model (G vs A)

Serum vitamin D (25(OH)D): ECC vs caries-free · Region: Asia (Fig 4)

dmfs index score · For interventions, pregnant women and mothers of infants in the first year of life; for outcomes, children up to 6…

Dental pain or sensitivity · Children and adults (with or without carious lesions) · 3 months, Children

Caries arrest · Children and adults (with or without carious lesions) · 12 to 30 months, Primary dentition

Enamel demineralization (DIAGNOdent) · Patients undergoing fixed orthodontic (fixed appliance) treatment (adolescents and adults, ages 12 to 35) · 1 and 6 months

Dental service utilisation within the past year · Adult residents of slums and non-slum urban settings of LMICs · Past 12 months

Dental caries / early childhood caries (ECC) · Children (approx. 4-18 years) · Adjustment for age: yes

Caries arrestment at the surface level · Children and adults with active dental caries (aged 1-50; mostly preschool/school children with primary dentition) · 12 to 18 months, SDF vs NAF

Overall success (composite of clinical and radiographic success) · Immature teeth, unspecified/mixed diagnosis

Antibacterial effect (Streptococcus mutans count, real-time PCR) · Patients undergoing fixed orthodontic (fixed appliance) treatment (adolescents and adults, ages 12 to 35) · 1 day to 6 months, Antibacterial (S. mutans)

Overall success (composite of clinical and radiographic success) · Partial pulpotomy, normal pulp/reversible pulpitis

First-time bracket failure · Patients undergoing fixed orthodontic treatment · Before and after treatment