Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

541 questions · 556 findings · 112 reviews · Headline outcomes only

No studies found 130 · 23.4%GRADE not reported 22 · 4%Very low 156 · 28.1%Low 151 · 27.2%Moderate 72 · 12.9%High 25 · 4.5%

Intervention not reported

Social support vs less intensive interventions 9 · Pregnant women who smoke

The intervention showed no clear difference in social support vs less intensive interventions 9 (high certainty).

1 finding from 1 review

Planned early birth vs expectant management

Admission to neonatal intensive care unit · preterm prelabour rupture of membranes (PPROM)

Planned early birth probably leads to higher admission to neonatal intensive care compared with expectant management (moderate certainty).

1 finding from 1 review

Cuffed vs uncuffed tubes

Need for intensive care unit (ICU) admission to treat post extubation stridor (as defined by the trial authors) · Children up to eight years undergoing general anaesthesia

It is very uncertain whether cuffed changes need for intensive care unit (ICU) admission to treat post… compared with uncuffed tubes (very low certainty).

1 finding from 1 review

Amnioinfusion vs no amnioinfusion

Perinatal death or severe morbidity · pregnant women with confirmed or suspected chorioamnionitis

The review found no eligible studies for this question.

1 finding from 1 review

Reduced number of antenatal care visits/goal‐oriented vs standard antenatal care visits

Admission to neonatal intensive care unit · Pregnant women at low risk of complications

Reduced number of antenatal care visits/goal‐oriented showed no clear difference in neonatal intensive care unit admission compared with standard antenatal care visits (moderate certainty).

1 finding from 1 review