Cochrane · systematic review · CD005302
Planned early birth versus expectant management (waiting) for prelabour rupture of membranes at term (37 weeks or more)
Middleton, P, Shepherd, E, Flenady, V, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library
Pregnancy and ChildbirthAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 2 · 33.3%Low 3 · 50%Moderate 1 · 16.7%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Planned early birth versus expectant management for prelabour rupture of the membranes at term
Population: women with prelabour rupture of membranes at term (37 weeks' gestation or later)
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Maternal infectious morbidity (chorioamnionitis and/or endometritis) Planned early birth vs expectant management | RR 0.49 [0.33, 0.72] | 8 studies · 6864 participants | Low Downgraded: risk of bias |
Caesarean section Planned early birth vs expectant management | RR 0.84 [0.69, 1.04] | 23 studies · 8576 participants | Low Downgraded: risk of bias |
Serious maternal morbidity or mortality (e.g. death, cardiac arrest, respiratory arrest, admission to intensive care unit) Planned early birth vs expectant management | no estimate extracted | 3 studies · 425 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Definite early‐onset neonatal sepsis Planned early birth vs expectant management | RR 0.57 [0.24, 1.33] | 6 studies · 1303 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Definite or probable early‐onset neonatal sepsis Planned early birth vs expectant management | RR 0.73 [0.58, 0.92] | 16 studies · 7314 participants | Low Downgraded: risk of bias |
Perinatal mortality (stillbirth or neonatal mortality) Planned early birth vs expectant management | RR 0.47 [0.13, 1.66] | 8 studies · 6392 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency, indirectness |