Cochrane · systematic review · CD011151
Intraoperative use of low volume ventilation to decrease postoperative mortality, mechanical ventilation, lengths of stay and lung injury in adults without acute lung injury
Guay, J, Ochroch, EA, Kopp, S · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 14.3%Low 3 · 42.9%Moderate 3 · 42.9%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Show all 2 versionsLow tidal volume compared to high tidal volume for surgery
Population: adults (aged > 16 years) without acute lung injury needing mechanical positive pressure ventilation during their surgery and undergoing any type of open or laparoscopic surgery, elective or emergency
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mortality Low tidal volume vs high tidal volume | RR 0.8 [0.42, 1.53] | 12 studies · 1207 participants | Low Downgraded: risk of bias, imprecision |
Pneumonia Low tidal volume vs high tidal volume | RR 0.45 [0.25, 0.82] | 7 studies · 778 participants | Moderate Downgraded: imprecision |
Need for postoperative non‐invasive ventilatory support Low tidal volume vs high tidal volume | RR 0.31 [0.15, 0.64] | 3 studies · 506 participants | Moderate Downgraded: imprecision |
Need for postoperative invasive ventilatory support Low tidal volume vs high tidal volume | RR 0.33 [0.14, 0.77] | 11 studies · 957 participants | Moderate Downgraded: imprecision |
Intensive care unit length of stay (days) Low tidal volume vs high tidal volume | no estimate extracted | 5 studies · 898 participants | Low Downgraded: risk of bias, inconsistency |
Hospital length of stay (days) Low tidal volume vs high tidal volume | no estimate extracted | 14 studies · 1298 participants | Low Downgraded: risk of bias, inconsistency |
Barotrauma: pneumothorax Low tidal volume vs high tidal volume | RR 1.77 [0.52, 5.99] | 5 studies · 708 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |