Cochrane · systematic review · CD004735
Planned early birth versus expectant management for women with preterm prelabour rupture of membranes prior to 37 weeks' gestation for improving pregnancy outcome
Bond, DM, Middleton, P, Levett, KM, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library
Pregnancy and ChildbirthAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 4 · 57.1%High 3 · 42.9%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Planned early birth compared to expectant management for preterm prelabour rupture of membranes prior to 37 weeks' gestation
Population: women with preterm prelabour rupture of membranes prior to 37 weeks' gestation
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Neonatal infection/sepsis Planned early birth vs expectant management | RR 0.93 [0.66, 1.3] | 12 studies · 3628 participants | Moderate Downgraded: imprecision |
Neonatal respiratory distress syndrome Planned early birth vs expectant management | RR 1.26 [1.05, 1.53] | 12 studies · 3622 participants | High |
Need for ventilation Planned early birth vs expectant management | RR 1.27 [1.02, 1.58] | 7 studies · 2895 participants | High |
Admission to neonatal intensive care Planned early birth vs expectant management | RR 1.16 [1.08, 1.24] | 4 studies · 2691 participants | Moderate Downgraded: imprecision |
Caesarean section Planned early birth vs expectant management | RR 1.26 [1.11, 1.44] | 12 studies · 3620 participants | High |
Chorioamnionitis Planned early birth vs expectant management | RR 0.5 [0.26, 0.95] | 8 studies · 1358 participants | Moderate Downgraded: inconsistency |
Length of hospital stay (maternal) Planned early birth vs expectant management | no estimate extracted | 6 studies · 2848 participants | Moderate Downgraded: inconsistency |