Cochrane · systematic review · CD011954
Cuffed versus uncuffed endotracheal tubes for general anaesthesia in children aged eight years and under
De Orange, FA, Andrade, RGAC, Lemos, A, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library
AnaesthesiaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 6 · 85.7%Low 1 · 14.3%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Cuffed vs uncuffed tubes for children up to eight years undergoing general anaesthesia
Population: Children up to eight years undergoing general anaesthesia
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Postextubation stridor (defined as any inspiratory sound or persistent barking, or presence of sternal or intercostal retractions postextubation) Cuffed vs uncuffed tubes | RR 0.93 [0.65, 1.33] | 2 studies · 2734 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Need for ETT exchange (defined as more than one attempt to arrive at the final endotracheal tube size) Cuffed vs uncuffed tubes | RR 0.07 [0.05, 0.1] | 2 studies · 2734 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Need for tracheal re‐intubation for postoperative stridor (defined as the need to re‐intubate to assure oxygenation to deal with postextubation stridor) Cuffed vs uncuffed tubes | RR 1.85 [0.17, 19.76] | 2 studies · 115 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Need for epinephrine to treat stridor (defined as the need to use epinephrine to treat postextubation stridor) Cuffed vs uncuffed tubes | RR 0.7 [0.38, 1.28] | 2 studies · 115 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Need for intensive care unit (ICU) admission to treat post extubation stridor (as defined by the trial authors) Cuffed vs uncuffed tubes | RR 2.77 [0.3, 25.78] | 1 study · 102 participants | Very low Downgraded: risk of bias, imprecision |
Cost of medical gas (described in the study by the hospital expenses for medical gases per participant in Euros) Cuffed vs uncuffed tubes | no estimate extracted | 1 study · 70 participants | Low Downgraded: risk of bias, imprecision |
Need for corticosteroid to treat stridor (defined as the need to use corticosteroid to treat postextubation stridor) Cuffed vs uncuffed tubes | RR 0.87 [0.51, 1.49] | 1 study · 102 participants | Very low Downgraded: risk of bias, imprecision |