Formula showed no clear difference in all‐cause mortality compared with donor breast milk (moderate certainty).
Transcatheter aortic valve implantation showed no clear difference in all‐cause mortality compared with surgical aortic valve replacement (moderate certainty).
Kangaroo mother care probably leads to lower mortality at latest compared with conventional neonatal care (moderate certainty).
Summary of findings: quinolone prophylaxis probably leads to higher all cause‐mortality compared with TMP‐SMZ prophylaxis (moderate certainty).
The intervention showed no clear difference in all‐cause mortality (moderate certainty).
The intervention showed no clear difference in all‐cause mortality low risk of bias Mortality (high certainty).
It is very uncertain whether the intervention changes reported mortality, low risk of bias studies only (very low certainty).
It is very uncertain whether hypertonic saline changes mortality at 6 months compared with other intracranial pressure‐lowering agents (very low certainty).
Neuraxial showed no clear difference in mortality－At any time compared with general anaesthesia (low certainty).
FIBRINOGEN: Therapeutic trials: intervention showed no clear difference in all‐cause mortality Up to 28 days following admission compared with inactive Control (moderate certainty).
The review found no eligible studies for this question.
It is very uncertain whether geriatrician‐led inpatient management changes mortality at 12 months compared with orthopaedic‐led inpatient management (very low certainty).
It is very uncertain whether hypertonic saline changes mortality (short‐term) compared with other intracranial pressure‐lowering agents (very low certainty).
Highest showed no clear difference in cancer mortality risk No. of participants: 17,448 (1 RCT) compared with lowest selenium exposure (high certainty).
Monoclonal antibodies leads to lower anti‐cytokine, all‐cause mortality ‐ low risk of bias studies compared with placebo (high certainty).
Monoclonal antibodies showed no clear difference in anti‐endotoxin, all‐cause mortality ‐ low risk of bias studies compared with placebo (moderate certainty).
It is very uncertain whether corticosteroid therapy changes number of deaths at 30 days following admission (30‐day mortality)a compared with no corticosteroid therapy (very low certainty).
Polyclonal intravenous immunoglobulin (IVIG) showed no clear difference in low risk of bias adult studies, by type of polyclonal IVIG,… compared with placebo or no intervention (high certainty).
Polyclonal intravenous immunoglobulin (IVIG) showed no clear difference in low risk of bias neonate studies, mortality all‐cause ‐ standard IVIG compared with placebo or no intervention (high certainty).
In prospective cohorts, the multivariable-adjusted HR for all-cause mortality in edentulous adults (0 teeth) vs adults with 1-32 teeth was 1.30 (95% CI 1.21 to 1.40; 7 studies, I2=20%); GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).