Cochrane · systematic review · CD003590
Interventions for protecting renal function in the perioperative period
Zacharias, M, Mugawar, M, Herbison, GP, et al. · Cochrane Database of Systematic Reviews · 2013 · Cochrane Library
AnaesthesiaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 4 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Interventions in patients with pre‐existing renal dysfunction
Population: patients with pre‐existing renal impairment
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mortality in patients with pre‐existing renal impairment As reported in the included trials Folliow‐up: 7 days | OR 0.74 [0.36, 1.52] | 10 studies · 959 participants | Very low Downgraded: inconsistency |
Acute renal injury in patients with pre‐existing renal impairment As reported in the included trials | OR 0.4 [0.22, 0.76] | 11 studies · 979 participants | Very low Downgraded: inconsistency |
Interventions to protect the kidneys in the perioperative period in patients undergoing surgery: low ROB studies only
Population: patients undergoing surgery
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Reported mortality, low risk of bias studies only | OR 1.01 [0.52, 1.97] | 19 studies · 1604 participants | Very low Downgraded: inconsistency |
Acute renal injury, low‐risk studies only | OR 1.05 [0.55, 2.03] | 16 studies · 1550 participants | Very low Downgraded: inconsistency |