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What do systematic reviews say?

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Evidence found and GRADE certainty

398 questions · 434 findings · 166 reviews

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No studies found 95 · 21.9%GRADE not reported 31 · 7.1%Very low 91 · 21%Low 110 · 25.3%Moderate 78 · 18%High 29 · 6.7%

Mortality: prone position vs supine

Subgroup analysis of longer‐term mortality: lower tidal volume ventilationAlive or dead · adults with acute respiratory failure

Mortality: prone position probably leads to lower subgroup analysis of longer‐term mortality: lower tidal volume… compared with supine (moderate certainty).

1 finding from 1 review

Intervention not reported

Perinatal/neonatal death or severe neonatal morbidity ‐ Low national perinatal mortality rate · women with term breech delivery

The intervention probably leads to lower perinatal/neonatal death or severe neonatal morbidity ‐ Low national… (moderate certainty).

1 finding from 1 review

Direct thrombin inhibitors vs low molecular weight heparin

All‐cause Mortality events · patients with prevention of venous thromboembolism following total hip or knee replacement

Direct thrombin inhibitors probably leads to higher all‐cause Mortality events compared with low molecular weight heparins (moderate certainty).

1 finding from 1 review

Stapler vs scalpel resection followed by hand‐sewn closure of the pancreatic remnant

All‐cause mortality · people undergoing distal pancreatectomy

Stapler showed no clear difference in mortality compared with scalpel resection followed by hand‐sewn closure of the pancreatic… (moderate certainty).

1 finding from 1 review

Intervention not reported

Mortality · adults and children with clinical signs and symptoms of acute lower respiratory tract infection

The review found no eligible studies for this question.

1 finding from 1 review

Drain use vs No drain

All‐cause mortality · people undergoing elective pancreatic resections

Drain use showed no clear difference in mortality compared with no drain use following pancreatic surgery (low certainty).

2 findings from 1 review

Early vs late drain removal following pancreatic surgery

All‐cause mortality · people undergoing elective pancreatic resections

It is very uncertain whether early changes mortality compared with late drain removal following pancreatic surgery (very low certainty).

2 findings from 1 review

Active drain vs passive drain

All‐cause mortality · people undergoing elective pancreatic resections

It is very uncertain whether active drain changes mortality compared with passive drain following pancreatic surgery (very low certainty).

2 findings from 1 review