Cochrane · systematic review · CD010583

Prophylactic abdominal drainage for pancreatic surgery

He, S, Xia, J, Zhang, W, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library

Gut4 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
21
current version
GRADE rated
18
No studies
3
Included studies
NR
No studies 3 · 14.3%Ungraded 0 · 0%Very low 12 · 57.1%Low 5 · 23.8%Moderate 1 · 4.8%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Show all 4 versions

Drain use versus no drain use following pancreatic surgery

Population: people undergoing elective pancreatic resections
7 questions
OutcomeEffectEvidenceStatus / GRADE
Mortality
Drain use vs no drain use following pancreatic surgery
RR 0.78 [0.31, 1.99]4 studies · 1055 participantsLow
Downgraded: risk of bias, imprecision
Mortality
Drain use vs no drain use following pancreatic surgery
RR 0.23 [0.06, 0.9]2 studies · 478 participantsLow
Downgraded: risk of bias, imprecision
Intra‐abdominal infection
Drain use vs no drain use following pancreatic surgery
RR 0.97 [0.52, 1.8]4 studies · 1055 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Wound infection
Drain use vs no drain use following pancreatic surgery
RR 0.98 [0.68, 1.41]4 studies · 1055 participantsLow
Downgraded: risk of bias, imprecision
Drain‐related complications
Drain use vs no drain use following pancreatic surgery
no estimate extracted1 study · 179 participantsLow
Downgraded: risk of bias, imprecision
Morbidity
Drain use vs no drain use following pancreatic surgery
RR 1.03 [0.94, 1.13]4 studies · 1055 participantsModerate
Downgraded: risk of bias
Length of hospital stay
Drain use vs no drain use following pancreatic surgery
no estimate extracted3 studies · 876 participantsLow
Downgraded: risk of bias

Active drain versus passive drain following pancreatic surgery

Population: people undergoing elective pancreatic resections
7 questions
OutcomeEffectEvidenceStatus / GRADE
Mortality
Active drain vs passive drain following pancreatic surgery
RR 1.23 [0.3, 5.06]2 studies · 382 participantsVery low
Downgraded: risk of bias, imprecision
Mortality
Active drain vs passive drain following pancreatic surgery
no estimate extractedNRNo studies
Intra‐abdominal infection
Active drain vs passive drain following pancreatic surgery
RR 0.87 [0.21, 3.66]2 studies · 321 participantsVery low
Downgraded: risk of bias, imprecision
Wound infection
Active drain vs passive drain following pancreatic surgery
RR 0.92 [0.44, 1.9]2 studies · 321 participantsVery low
Downgraded: risk of bias, imprecision
Drain‐related complications
Active drain vs passive drain following pancreatic surgery
no estimate extracted1 study · 223 participantsVery low
Downgraded: risk of bias, imprecision
Morbidity
Active drain vs passive drain following pancreatic surgery
RR 0.97 [0.53, 1.77]2 studies · 382 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Length of hospital stay
Active drain vs passive drain following pancreatic surgery
no estimate extracted2 studies · 321 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency

Early versus late drain removal following pancreatic surgery

Population: people undergoing elective pancreatic resections
7 questions
OutcomeEffectEvidenceStatus / GRADE
Mortality
Early vs late drain removal following pancreatic surgery
RR 0.99 [0.06, 15.45]3 studies · 399 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Mortality
Early vs late drain removal following pancreatic surgery
no estimate extractedNRNo studies
Intra‐abdominal infection
Early vs late drain removal following pancreatic surgery
RR 0.44 [0.22, 0.89]2 studies · 285 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Wound infection
Early vs late drain removal following pancreatic surgery
RR 1.32 [0.45, 3.85]2 studies · 285 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Drain‐related complications
Early vs late drain removal following pancreatic surgery
no estimate extractedNRNo studies
Morbidity
Early vs late drain removal following pancreatic surgery
RR 0.49 [0.3, 0.81]2 studies · 258 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Length of hospital stay
Early vs late drain removal following pancreatic surgery
no estimate extracted3 studies · 399 participantsVery low
Downgraded: risk of bias, imprecision, indirectness