Cochrane · systematic review · CD010583
Prophylactic abdominal drainage for pancreatic surgery
He, S, Xia, J, Zhang, W, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
21
current version
GRADE rated
18
No studies
3
Included studies
NR
No studies 3 · 14.3%Ungraded 0 · 0%Very low 12 · 57.1%Low 5 · 23.8%Moderate 1 · 4.8%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlyDrain use versus no drain use following pancreatic surgery
Population: people undergoing elective pancreatic resections
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mortality Drain use vs no drain use following pancreatic surgery | RR 0.78 [0.31, 1.99] | 4 studies · 1055 participants | Low Downgraded: risk of bias, imprecision |
Mortality Drain use vs no drain use following pancreatic surgery | RR 0.23 [0.06, 0.9] | 2 studies · 478 participants | Low Downgraded: risk of bias, imprecision |
Intra‐abdominal infection Drain use vs no drain use following pancreatic surgery | RR 0.97 [0.52, 1.8] | 4 studies · 1055 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Wound infection Drain use vs no drain use following pancreatic surgery | RR 0.98 [0.68, 1.41] | 4 studies · 1055 participants | Low Downgraded: risk of bias, imprecision |
Drain‐related complications Drain use vs no drain use following pancreatic surgery | no estimate extracted | 1 study · 179 participants | Low Downgraded: risk of bias, imprecision |
Morbidity Drain use vs no drain use following pancreatic surgery | RR 1.03 [0.94, 1.13] | 4 studies · 1055 participants | Moderate Downgraded: risk of bias |
Length of hospital stay Drain use vs no drain use following pancreatic surgery | no estimate extracted | 3 studies · 876 participants | Low Downgraded: risk of bias |
Active drain versus passive drain following pancreatic surgery
Population: people undergoing elective pancreatic resections
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mortality Active drain vs passive drain following pancreatic surgery | RR 1.23 [0.3, 5.06] | 2 studies · 382 participants | Very low Downgraded: risk of bias, imprecision |
Mortality Active drain vs passive drain following pancreatic surgery | no estimate extracted | NR | No studies |
Intra‐abdominal infection Active drain vs passive drain following pancreatic surgery | RR 0.87 [0.21, 3.66] | 2 studies · 321 participants | Very low Downgraded: risk of bias, imprecision |
Wound infection Active drain vs passive drain following pancreatic surgery | RR 0.92 [0.44, 1.9] | 2 studies · 321 participants | Very low Downgraded: risk of bias, imprecision |
Drain‐related complications Active drain vs passive drain following pancreatic surgery | no estimate extracted | 1 study · 223 participants | Very low Downgraded: risk of bias, imprecision |
Morbidity Active drain vs passive drain following pancreatic surgery | RR 0.97 [0.53, 1.77] | 2 studies · 382 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Length of hospital stay Active drain vs passive drain following pancreatic surgery | no estimate extracted | 2 studies · 321 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Early versus late drain removal following pancreatic surgery
Population: people undergoing elective pancreatic resections
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mortality Early vs late drain removal following pancreatic surgery | RR 0.99 [0.06, 15.45] | 3 studies · 399 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Mortality Early vs late drain removal following pancreatic surgery | no estimate extracted | NR | No studies |
Intra‐abdominal infection Early vs late drain removal following pancreatic surgery | RR 0.44 [0.22, 0.89] | 2 studies · 285 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Wound infection Early vs late drain removal following pancreatic surgery | RR 1.32 [0.45, 3.85] | 2 studies · 285 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Drain‐related complications Early vs late drain removal following pancreatic surgery | no estimate extracted | NR | No studies |
Morbidity Early vs late drain removal following pancreatic surgery | RR 0.49 [0.3, 0.81] | 2 studies · 258 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Length of hospital stay Early vs late drain removal following pancreatic surgery | no estimate extracted | 3 studies · 399 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Drain use versus no drain use for pancreatic surgery
Population: people undergoing elective open pancreatic resections
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mortality Drain use vs no drain use | RR 0.78 [0.31, 1.99] | 4 studies · 1055 participants | Moderate Downgraded: imprecision, publication bias |
Mortality Drain use vs no drain use | RR 0.23 [0.06, 0.9] | 2 studies · 478 participants | Moderate Downgraded: imprecision, publication bias |
Intra‐abdominal infection Drain use vs no drain use | RR 0.97 [0.52, 1.8] | 4 studies · 1055 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, publication bias |
Wound infection Drain use vs no drain use | RR 0.98 [0.68, 1.41] | 4 studies · 1055 participants | Low Downgraded: risk of bias, imprecision, publication bias |
Drain‐related complications Drain use vs no drain use | no estimate extracted | 1 study · 179 participants | Low Downgraded: risk of bias, imprecision, publication bias |
Morbidity Drain use vs no drain use | RR 1.03 [0.94, 1.13] | 4 studies · 1055 participants | Moderate Downgraded: risk of bias, publication bias |
Length of hospital stay Drain use vs no drain use | no estimate extracted | 3 studies · 711 participants | Moderate Downgraded: risk of bias, publication bias |
Hospital costs Drain use vs no drain use | no estimate extracted | NR | No studies |
Additional open procedures for postoperative complications Drain use vs no drain use | RR 1.33 [0.79, 2.23] | 4 studies · 1055 participants | Low Downgraded: risk of bias, imprecision, publication bias |
Additional radiological interventions for postoperative complications Drain use vs no drain use | RR 0.87 [0.4, 1.87] | 3 studies · 660 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, publication bias |
Pain Drain use vs no drain use | no estimate extracted | NR | No studies |
Quality of life Drain use vs no drain use | no estimate extracted | 1 study · 399 participants | Low Downgraded: risk of bias, imprecision, publication bias |
Active drain versus passive drain for pancreatic surgery
Population: people undergoing elective open pancreatic resections
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mortality Active drain vs passive drain | RR 2.86 [0.12, 69.06] | 1 study · 160 participants | Low Downgraded: imprecision, publication bias |
Mortality Active drain vs passive drain | no estimate extracted | NR | No studies |
Intra‐abdominal infection Active drain vs passive drain | RR 0.19 [0.01, 3.9] | 1 study · 160 participants | Very low Downgraded: risk of bias, imprecision, publication bias |
Wound infection Active drain vs passive drain | RR 0.68 [0.23, 2.05] | 1 study · 160 participants | Very low Downgraded: risk of bias, imprecision, publication bias |
Drain‐related complications Active drain vs passive drain | no estimate extracted | NR | No studies |
Morbidity Active drain vs passive drain | RR 0.68 [0.41, 1.15] | 1 study · 160 participants | Low Downgraded: risk of bias, imprecision, publication bias |
Length of hospital stay Active drain vs passive drain | no estimate extracted | 1 study · 160 participants | Low Downgraded: risk of bias, imprecision, publication bias |
Hospital costs Active drain vs passive drain | no estimate extracted | NR | No studies |
Additional open procedures for postoperative complications Active drain vs passive drain | RR 0.16 [0.02, 1.29] | 1 study · 160 participants | Very low Downgraded: risk of bias, imprecision, publication bias |
Additional radiological interventions for postoperative complications Active drain vs passive drain | no estimate extracted | NR | No studies |
Pain Active drain vs passive drain | no estimate extracted | NR | No studies |
Quality of life Active drain vs passive drain | no estimate extracted | NR | No studies |
Early versus late drain removal for pancreatic surgery
Population: people undergoing elective open pancreatic resections
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mortality Early vs late drain removal | no estimate extracted | 1 study · 114 participants | Moderate Downgraded: imprecision, publication bias |
Mortality Early vs late drain removal | no estimate extracted | NR | No studies |
Intra‐abdominal infection Early vs late drain removal | no estimate extracted | NR | No studies |
Wound infection Early vs late drain removal | no estimate extracted | NR | No studies |
Drain‐related complications Early vs late drain removal | no estimate extracted | NR | No studies |
Morbidity Early vs late drain removal | RR 0.63 [0.43, 0.93] | 1 study · 114 participants | Low Downgraded: risk of bias, imprecision, publication bias |
Length of hospital stay Early vs late drain removal | no estimate extracted | 1 study · 114 participants | Low Downgraded: risk of bias, imprecision, publication bias |
Hospital costs Early vs late drain removal | no estimate extracted | 1 study · 114 participants | Low Downgraded: risk of bias, imprecision, publication bias |
Additional open procedures for postoperative complications Early vs late drain removal | RR 0.33 [0.01, 8.01] | 1 study · 114 participants | Very low Downgraded: risk of bias, imprecision, publication bias |
Additional radiological interventions for postoperative complications Early vs late drain removal | no estimate extracted | NR | No studies |
Pain Early vs late drain removal | no estimate extracted | NR | No studies |
Quality of life Early vs late drain removal | no estimate extracted | NR | No studies |
Drain use versus no drain use for pancreatic surgery
Population: people undergoing elective open pancreatic resections
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mortality (30 days) Drain use vs no drain use | RR 0.78 [0.31, 1.99] | 3 studies · 711 participants | Low Downgraded: risk of bias, imprecision, publication bias |
Mortality (90 days) Drain use vs no drain use | RR 0.24 [0.05, 1.1] | 1 study · 134 participants | Low Downgraded: risk of bias, imprecision, publication bias |
Intra‐abdominal infection Drain use vs no drain use | RR 0.89 [0.36, 2.2] | 3 studies · 711 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, publication bias |
Drain‐related complications Drain use vs no drain use | no estimate extracted | 1 study · 179 participants | Low Downgraded: risk of bias, imprecision, publication bias |
Morbidity Drain use vs no drain use | RR 1.04 [0.93, 1.16] | 3 studies · 711 participants | Moderate Downgraded: risk of bias, publication bias |
Length of hospital stay Drain use vs no drain use | no estimate extracted | 3 studies · 711 participants | Moderate Downgraded: risk of bias, publication bias |
Active drain versus passive drain for pancreatic surgery
Population: people undergoing elective open pancreatic resections
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mortality (30 days) Active drain vs passive drain | RR 2.86 [0.12, 69.06] | 1 study · 160 participants | Very low Downgraded: risk of bias, imprecision, publication bias |
Intra‐abdominal infection Active drain vs passive drain | RR 0.19 [0.01, 3.9] | 1 study · 160 participants | Very low Downgraded: risk of bias, imprecision, publication bias |
Morbidity Active drain vs passive drain | RR 0.68 [0.41, 1.15] | 1 study · 160 participants | Low Downgraded: risk of bias, imprecision, publication bias |
Length of hospital stay Active drain vs passive drain | no estimate extracted | 1 study · 160 participants | Low Downgraded: risk of bias, imprecision, publication bias |
Early versus late drain removal for pancreatic surgery
Population: people undergoing elective open pancreatic resections
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mortality (30 days) Early vs late drain removal | no estimate extracted | 1 study · 114 participants | Low Downgraded: risk of bias, imprecision, publication bias |
Morbidity Early vs late drain removal | RR 0.63 [0.43, 0.93] | 1 study · 114 participants | Low Downgraded: risk of bias, imprecision, publication bias |
Length of hospital stay (days) Early vs late drain removal | no estimate extracted | 1 study · 114 participants | Low Downgraded: risk of bias, imprecision, publication bias |
Drain use versus no drain use for pancreatic surgery
Population: Patients undergoing elective open pancreatic resections
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mortality (30 days) Drain use vs no drain use | RR 0.44 [0.05, 3.94] | 2 studies · 316 participants | Very low Downgraded: risk of bias, imprecision, publication bias |
Mortality (90 days) Drain use vs no drain use | RR 0.24 [0.05, 1.1] | 1 study · 134 participants | Very low Downgraded: risk of bias, imprecision, publication bias |
Intra‐abdominal infection Drain use vs no drain use | RR 0.61 [0.25, 1.46] | 2 studies · 316 participants | Very low Downgraded: risk of bias, imprecision, publication bias |
Drain‐related complications Drain use vs no drain use | RR 3.1 [0.13, 75.12] | 1 study · 179 participants | Very low Downgraded: risk of bias, imprecision, publication bias |
Morbidity Drain use vs no drain use | RR 1.02 [0.88, 1.19] | 2 studies · 316 participants | Very low Downgraded: risk of bias, imprecision, publication bias |
Length of hospital stay Drain use vs no drain use | no estimate extracted | 2 studies · 316 participants | Very low Downgraded: risk of bias, imprecision, publication bias |
Early versus late drain removal for pancreatic surgery
Population: Patients undergoing elective open pancreatic resections
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mortality (30 days) Early vs late drain removal | no estimate extracted | 1 study · 114 participants | Low Downgraded: risk of bias, imprecision, publication bias |
Morbidity Early vs late drain removal | RR 0.63 [0.43, 0.93] | 1 study · 114 participants | Low Downgraded: risk of bias, imprecision, publication bias |
Length of hospital stay (days) Early vs late drain removal | no estimate extracted | 1 study · 114 participants | Low Downgraded: risk of bias, imprecision, publication bias |