Cochrane · systematic review · CD001704

Interventions for improving mobility after hip fracture surgery in adults

Fairhall, NJ, Dyer, SM, Mak, JCS, et al. · Cochrane Database of Systematic Reviews · 2022 · Cochrane Library

Bone, Joint and Muscle TraumaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
26
current version
GRADE rated
21
No studies
2
Included studies
NR
No studies 2 · 7.7%Ungraded 3 · 11.5%Very low 3 · 11.5%Low 9 · 34.6%Moderate 5 · 19.2%High 4 · 15.4%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Summary of findings: in‐hospital studies

Population: adults following hip fracture surgery
7 questions
OutcomeEffectEvidenceStatus / GRADE
Mobilityd ‐ overall analysis Using different mobility scales: MILA (range 0 to 36), EMS (range 0 to 20), BBS (range 0 to 56), PPME (range 0 to 12), Koval (range 1 to 7). Higher values indicate better mobility (except MILA and Koval, where scale wa...
SMD 0.53 [0.1, 0.96]7 studies · 507 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Walking speedg ‐ overall analysis Measured using metres/second (m/s) and metres/minute (m/min). A higher score indicates faster walking.
SMD 0.166 studies · 360 participantsModerate
Downgraded: risk of bias, imprecision
Functioningi ‐ overall analysis Using different scales: mBI (range 0 to 20), BI (range 0 to 100), FIM (range 18 to 126), NEADL (range 0 to 66). A higher score indicates better functioning.
SMD 0.75 [0.24, 1.26]7 studies · 379 participantsVery low
Downgraded: risk of bias, inconsistency
HRQoL Using EQ‐5D (range 0 to 1) and HOOS (range 0 to 100). A higher score indicates better quality of life.
SMD 0.394 studies · 314 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Mortality
RR 1.06 [0.48, 2.3]6 studies · 489 participantsLow
Downgraded: risk of bias, imprecision
Adverse event: number of people who were re‐admitted
RR 0.7 [0.44, 1.11]4 studies · 322 participantsLow
Downgraded: imprecision
Number of people who returned to living at pre‐fracture residence
RR 1.07 [0.73, 1.56]2 studies · 240 participantsLow
Downgraded: imprecision

Summary of findings: different types of intervention on mobility outcome, in‐hospital

Population: adults following hip fracture surgery
4 questions
OutcomeEffectEvidenceStatus / GRADE
Mobility outcome
no estimate extractedNRNo studies
Mobility scales, using different mobility scales: MILA (range 0 to 36), EMS (range 0 to 20), BBS (range 0 to 56), PPME (range 0 to 12), Koval (range 1 to 7). Higher values indicate better mobility (except MILA and Koval, where scale was inverted f...
SMD 0.57 [0.07, 1.06]6 studies · 463 participantsModerate
Downgraded: inconsistency
Mobility scales, using EMS (range 0 to 20). Higher values indicate better mobility
MD 11 study · 44 participantsLow
Downgraded: risk of bias, imprecision
TUG (lower score = faster)
no estimate extracted1 study · 74 participantsLow
Downgraded: risk of bias, imprecision

Summary of findings: post‐hospital studies

Population: adults following hip fracture surgery
6 questions
OutcomeEffectEvidenceStatus / GRADE
Mobilityd ‐ overall analysis Using different mobility scales: mPPT (range 0 to 36), POMA (range 0 to 30), SPPB (range 0 to 12), PPME (range 0 to 12). A higher score indicates better mobility.
SMD 0.32 [0.11, 0.54]7 studies · 761 participantsHigh
Walking speedg ‐ overall analysis Measured using metres/second (m/s) and metres/minute (m/min). A higher score indicates faster walking.
SMD 0.16 [0.04, 0.29]14 studies · 1067 participantsHigh
Functioningi ‐ overall analysis Using different functioning scales: FSQ (range 0 to 36), BI (range 0 to 100), AM‐PAC daily activity (range 9 to 101), COPM (range 0 to 20), LEFS (range 0 to 80), NEADL (range 0 to 66). A higher score indicates bette...
SMD 0.23 [0.1, 0.36]9 studies · 936 participantsHigh
HRQoL using EQ‐ 5D (range 0 to 1), SF‐36 (range 0 to 100), SF‐12 (range 0 to 100), and WHOQOL‐BREF (range 0 to 130). A higher score indicates better quality of life.
SMD 0.14 [0, 0.29]10 studies · 785 participantsModerate
Downgraded: risk of bias
Mortality
RR 1.01 [0.49, 2.06]8 studies · 737 participantsModerate
Downgraded: risk of bias, imprecision
Adverse event: number of people who were re‐admitted
RR 0.86 [0.52, 1.42]2 studies · 206 participantsLow
Downgraded: risk of bias, imprecision

Summary of findings: different types of intervention on mobility outcome, post‐hospital

Population: adults following hip fracture surgery
9 questions
OutcomeEffectEvidenceStatus / GRADE
Mobility outcome
no estimate extractedNRNo studies
Mobility scales, using different scales: SPPB (range 0 to 12), PPME (range 0 to 12). A higher score indicates better mobility.
SMD 0.2 [0.05, 0.36]5 studies · 621 participantsHigh
TUG (lower score = faster)
no estimate extracted1 study · 128 participantsVery low
Downgraded: risk of bias, imprecision
Minute Walk Test
no estimate extracted0 participantsUngraded
Mobility scales
no estimate extracted0 participantsUngraded
TUG
no estimate extracted1 study · 96 participantsLow
Downgraded: imprecision
6MWT
MD 55.65 [28.58, 82.72]3 studies · 198 participantsLow
Downgraded: risk of bias, imprecision
All
no estimate extracted0 participantsUngraded
Mobility scales, using different mobility scales: mPPT (range 0 to 36), POMA (range 0 to 30).
SMD 0.94 [0.53, 1.34]2 studies · 104 participantsModerate
Downgraded: imprecision