Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

53 questions · 54 findings · 36 reviews

No studies found 9 · 16.7%GRADE not reported 9 · 16.7%Very low 19 · 35.2%Low 9 · 16.7%Moderate 6 · 11.1%High 2 · 3.7%

Higher vs lower FiO2 or targets of arterial oxygenation

Proportion of participants with 1 or more serious adverse events according to International Conference on Harmonisation Good Clinical Practice (ICH‐GCP) · adults admitted to the ICU

It is very uncertain whether higher changes proportion of participants with ≥ 1 serious adverse events according… compared with lower FiO2 or targets of arterial oxygenation (very low certainty).

1 finding from 1 review

High‐dose vs low‐dose colchicine

Total adverse events · acute gout

High‐dose may leads to higher total adverse events compared with low‐dose colchicine (low certainty).

1 finding from 1 review