It is very uncertain whether early ART changes cryptococcal IRIS compared with delayed ART initiation (very low certainty).
It is very uncertain whether early ART changes HIV virological suppression at 6 months (viral load < 400 copies/mL) compared with delayed ART initiation (very low certainty).
INTERMITTENT (EARLY‐BASED) may leads to higher leaving the study early/loss to compared with MAINTENANCE THERAPY (low certainty).
Very early discharge may leads to lower treatment failure; death compared with early discharge (low certainty).
The review found no eligible studies for this question.
Very early discharge may leads to lower duration of total antimicrobial treatment compared with early discharge (low certainty).
Very early discharge may leads to lower duration of intravenous antimicrobial treatment compared with early discharge (low certainty).
Very early discharge may leads to lower duration of oral antimicrobial treatment compared with early discharge (low certainty).
The review found no eligible studies for this question.
Very early discharge showed no clear difference in treatment failure; rehospitalization or adjustment of antimicrobial… compared with early discharge (low certainty).
Very early discharge showed no clear difference in treatment failure; rehospitalization or adjustment of antimicrobial… compared with early discharge (low certainty).
Early routine ERCP strategy showed no clear difference in all‐cause mortality, ITT analysis compared with early conservative management with or without delayed or selective… (low certainty).
Early routine ERCP strategy showed no clear difference in local complications defined by the Atlanta Classification (necrosis,… compared with early conservative management with or without delayed or selective… (moderate certainty).
Early routine ERCP strategy showed no clear difference in systemic complications defined by the Atlanta Classification (organ… compared with early conservative management with or without delayed or selective… (moderate certainty).
Early hCG showed no clear difference in pregnancy rate per couple compared with late hCG (low certainty).
It is very uncertain whether early hCG changes miscarriage rate compared with late hCG (very low certainty).
Early ART probably leads to lower death compared with standard or deferred ART (CD4 <= 200 or CD4 <= 250 cells/µl) (moderate certainty).
Early ART showed no clear difference in tuberculosis compared with standard or deferred ART (CD4 <= 200 or CD4 <= 250 cells/µl) (moderate certainty).
Early ART showed no clear difference in disease progression measured by opportunistic disease Opportunistic… compared with standard or deferred ART (CD4 <= 200 or CD4 <= 250 cells/µl) (low certainty).
It is very uncertain whether early surgery changes complete recovery of facial nerve function at 12 months Defined as:… compared with late surgery (very low certainty).