Cochrane · systematic review · CD009779
Early routine endoscopic retrograde cholangiopancreatography strategy versus early conservative management strategy in acute gallstone pancreatitis
Tse, F, Yuan, Y · Cochrane Database of Systematic Reviews · 2012 · Cochrane Library
GutAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
3
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 33.3%Moderate 2 · 66.7%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Early routine ERCP strategy compared to early conservative management with or without delayed or selective ERCP strategy in unselected patients with acute gallstone pancreatitis: main analyses for mortality, local and systemic complications (organ failure) as defined by the Atlanta Classification
Population: patients with unselected patients with acute gallstone pancreatitis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
All‐cause mortality, ITT analysis Early routine ERCP strategy vs early conservative management with or without delayed or selective ERCP strategy | RR 0.74 [0.18, 3.03] | 5 studies · 644 participants | Low Downgraded: inconsistency, publication bias |
Local complications defined by the Atlanta Classification (necrosis, abscess, pseudocyst) Early routine ERCP strategy vs early conservative management with or without delayed or selective ERCP strategy | RR 0.86 [0.52, 1.43] | 4 studies · 517 participants | Moderate Downgraded: publication bias |
Systemic complications defined by the Atlanta Classification (organ failure including shock, pulmonary insufficiency, renal failure, and gastrointestinal bleeding; disseminated intravascular coagulation or severe metabolic disturbances) Early routine ERCP strategy vs early conservative management with or without delayed or selective ERCP strategy | RR 0.59 [0.31, 1.11] | 4 studies · 406 participants | Moderate Downgraded: publication bias |