Studies
Primary studies
5,083 studies included by 199 non-Cochrane dental reviews extracted from full text, one record per study, so a study included by several reviews is counted once. Most are randomized trials; etiology and diagnostic reviews also include observational and accuracy studies. Cochrane reviews and reviews with only their headline outcomes do not list their included studies here yet.
| Study | Year | Reviews | Review outcomes linked | Trial data |
|---|---|---|---|---|
| Feeding and smoking habits as cumulative risk factors for early childhood caries in toddlers, after adjustment for several behavioral determinants:… Majorana et al. (2014) · Majorana Alessandra, Cagetti Maria Grazia, et al. · BMC pediatrics PMID:24528500 | 2014 | 5 | 4 | not extracted yet |
| Associations Between Prenatal, Perinatal, and Early Childhood Vitamin D Status and Risk of Dental Caries at 6 Years. Andaur Navarro et al. 2021 · Navarro Constanza L Andaur, Grgic Olja, et al. · The Journal of nutrition PMID:33982112 | 2021 | 3 | 2 | not extracted yet |
| Factors associated with early childhood caries among 3 to 6 year old children in India: A case control study Sridevi 2018 · Sridevi T., Pranoti S., et al. · Journal of Neonatal-Perinatal Medicine DOI:10.3233/npm-181723 | 2018 | 3 | 2 | not extracted yet |
| Risk indicators for early childhood caries in 2‐year‐old children in southern China Zhou 2011 · Zhou Y, Lin HC, et al. · Australian Dental Journal DOI:10.1111/j.1834-7819.2010.01280.x | 2010 | 3 | 2 | not extracted yet |
| Effectiveness of nanosilver fluoride and silver diamine fluoride in arresting early childhood caries: a randomized controlled clinical trial. Quritum et al. 2024 · Quritum Maryam, Abdella Ahmed, et al. · BMC oral health PMID:38890627 | 2024 | 2 | none stated | not extracted yet |
| Silver diamine fluoride with sodium fluoride varnish versus silver diamine fluoride in arresting early childhood caries: a 6-months follow up of a… Abdellatif et al. 2023 · Abdellatif Enas B, El Kashlan Mona K, et al. · BMC oral health PMID:37978488 | 2023 | 2 | none stated | not extracted yet |
| Candida species and selected behavioral factors co-associated with severe early childhood caries: Case-control study. Cvanova M 2022 · Cvanova Michaela, Ruzicka Filip, et al. · Frontiers in cellular and infection microbiology PMID:35959372 | 2022 | 2 | 1 | not extracted yet |
| Risk Factors for Early Childhood Caries in Three-Year-Old Japanese Children: A Prospective Cohort Study. Nakayama 2022 · Nakayama Yoshimi, Ohnishi Hirofumi · Pediatric dentistry PMID:36309780 | 2022 | 2 | 1 | not extracted yet |
| Does the Trimester of Smoking Matter in the Association between Prenatal Smoking and the Risk of Early Childhood Caries? Akinkugbe 2021 · Akinkugbe Aderonke A · Caries research PMID:33508853 | 2021 | 2 | 1 | not extracted yet |
| Association of Candida albicans and Cbp+ Streptococcus mutans with early childhood caries recurrence. Garcia BA 2021 · Garcia B A, Acosta N C, et al. · Scientific reports PMID:34031498 | 2021 | 2 | 1 | not extracted yet |
| Association between the incidence of early childhood caries and attending childcare among toddlers in a rural area of Japan: a prospective cohort… Yokoi 2021 · Yokoi Aya, Takeuchi Noriko, et al. · Acta Odontologica Scandinavica DOI:10.1080/00016357.2020.1795249 | 2020 | 2 | none stated | not extracted yet |
| Early childhood feeding practices and dental caries among Australian preschoolers Devenish 2020 · Devenish Gemma, Mukhtar Aqif, et al. · The American Journal of Clinical Nutrition DOI:10.1093/ajcn/nqaa012 | 2020 | 2 | none stated | not extracted yet |
| Arresting early childhood caries using silver and fluoride products - A randomised trial. Gao et al. 2020 · Gao Sherry Shiqian, Chen Kitty Jieyi, et al. · Journal of dentistry PMID:33166594 | 2020 | 2 | none stated | not extracted yet |
| Association between early childhood caries and malnutrition in a sub-urban population in Nigeria. Folayan 2019 · Folayan Morenike Oluwatoyin, Arije Olujide, et al. · BMC pediatrics PMID:31722683 | 2019 | 2 | 1 | not extracted yet |
| Temporal development of the oral microbiome and prediction of early childhood caries. Dashper 2019 · Dashper S G, Mitchell H L, et al. · Scientific reports PMID:31874981 | 2019 | 2 | none stated | not extracted yet |
| Investigation of Interaction between Vitamin D Receptor Gene Polymorphisms and Environmental Factors in Early Childhood Caries in Chinese Children. Qin 2019 · Qin Xiurong, Shao Linqin, et al. · BioMed research international PMID:31930121 | 2019 | 2 | 5 | not extracted yet |
| Influence of mode of delivery, family and nursing determinants on early childhood caries development: a prospective cohort study Boustedt 2018 · Boustedt Katarina, Roswall Josefine, et al. · Acta Odontologica Scandinavica DOI:10.1080/00016357.2018.1490965 | 2018 | 2 | 2 | not extracted yet |
| Suboptimal Serum Vitamin D Associated with Early Childhood Caries in Special Health Care Needs Children. Seminario et al. 2018 · Seminario Ana Lucia, Jumani Ketan, et al. · Journal of dentistry for children (Chicago, Ill.) PMID:30869584 | 2018 | 2 | 1 | not extracted yet |
| Antenatal Health Care and Postnatal Dental Check-Ups Prevent Early Childhood Caries Nakai 2016 · Nakai Yukie, Mori Yukako, et al. · The Tohoku Journal of Experimental Medicine DOI:10.1620/tjem.240.303 | 2016 | 2 | 2 | not extracted yet |
| Severe early childhood caries and social determinants in three-year-old children from Northern Thailand: a birth cohort study. Peltzer et al. 2015 · Peltzer Karl, Mongkolchati Aroonsri · BMC oral health PMID:26370287 | 2015 | 2 | 1 | not extracted yet |
| Mode of delivery, mutans streptococci colonization, and early childhood caries in three- to five-year-old Thai children. Pattanaporn 2013 · Pattanaporn K, Saraithong P, et al. · Community dentistry and oral epidemiology PMID:23106389 | 2013 | 2 | 2 | not extracted yet |
| Vitamin D status of children with severe early childhood caries: a case-control study. Schroth et al. 2013 · Schroth Robert J, Levi Jeremy A, et al. · BMC pediatrics PMID:24160554 | 2013 | 2 | 1 | not extracted yet |
| Association between prolonged breast‐feeding and early childhood caries: a hierarchical approach Nunes 2012 · Nunes Ana Margarida Melo, Alves Claudia Maria Coelho, et al. · Community Dentistry and Oral Epidemiology DOI:10.1111/j.1600-0528.2012.00703.x | 2012 | 2 | none stated | not extracted yet |
| The relationship between vitamin D and severe early childhood caries: a pilot study. Schroth et al. 2012 · Schroth Robert J, Jeal Nathan S, et al. · International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition PMID:22811377 | 2012 | 2 | 1 | not extracted yet |
| Early Feeding Practices and Severe Early Childhood Caries in Four-Year-Old Children from Southern Brazil: A Birth Cohort Study Feldens 2010 · Feldens C.A., Giugliani E.R.J., et al. · Caries Research DOI:10.1159/000319898 | 2010 | 2 | none stated | not extracted yet |
| Early feeding practices and severe early childhood caries in four-year-old children from southern Brazil: a birth cohort study. Feldens et al. 2010 · Feldens C A, Giugliani E R J, et al. · Caries research PMID:20838043 | 2010 | 2 | 1 | not extracted yet |
| Spontaneous space closure in patients treated with early extraction of the first permanent molar: a retrospective cohort study using radiographs. Aldahool 2024 · Aldahool Yasser, Sonesson Mikael, et al. · The Angle orthodontist PMID:38381800 | 2024 | 1 | none stated | not extracted yet |
| Microbiological Evaluation of Herbal Extracts against Candida albicans in Early Childhood Caries Patients: An In Vitro Study. Siddaiah SB 2024 · Siddaiah Shakuntala B, Sinha Somya, et al. · International journal of clinical pediatric dentistry PMID:38559866 | 2024 | 1 | 1 | not extracted yet |
| Effectiveness of silver diamine fluoride in arresting early childhood caries: a randomised controlled clinical trial. ElGhandour 2024 · ElGhandour R K, ElTekeya M M H, et al. · European journal of paediatric dentistry PMID:38888598 | 2024 | 1 | none stated | not extracted yet |
| Presence of candida in the dental plaque and saliva of patients with severe early childhood caries and early childhood caries:a pilot study. Esra O 2024 · Ozgocmen Esra, Yigit Tugba, et al. · European oral research PMID:39011175 | 2024 | 1 | 1 | not extracted yet |
| Is the answer to reducing early childhood caries in your pocket? Fegan 2023 · Fegan Helen, Hutchinson Rachel · Evidence-Based Dentistry DOI:10.1038/s41432-023-00922-3 | 2023 | 1 | none stated | not extracted yet |
| Early Sugar Introduction Associated with Early Childhood Caries Occurrence. Echeverria et al. 2023 · Echeverria Mariana Silveira, Schuch Helena Silveira, et al. · Caries research PMID:36682347 | 2023 | 1 | 1 | not extracted yet |
| App-based oral health promotion interventions on modifiable risk factors associated with early childhood caries: A systematic review. Ajay 2023 · Ajay Kamalapriya, Azevedo Liane B, et al. · Frontiers in oral health PMID:36968137 | 2023 | 1 | none stated | not extracted yet |
| Early Childhood Predictors for Dental Caries: A Machine Learning Approach. Toledo Reyes (2023) · Toledo Reyes L, Knorst J K, et al. · Journal of dental research PMID:37246832 | 2023 | 1 | none stated | not extracted yet |
| Relationship between the salivary concentrations of proteinase-3 and interleukin-8 and severe early childhood caries. Biria 2023 · Biria Mina, Sattari Mandana, et al. · Dental and medical problems PMID:38108476 | 2023 | 1 | none stated | not extracted yet |
| Prediction model for early childhood caries risk based on behavioral determinants using a machine learning algorithm Qu 2022 · Qu Xing, Zhang Chao, et al. · Computer Methods and Programs in Biomedicine DOI:10.1016/j.cmpb.2022.107221 | 2022 | 1 | 1 | not extracted yet |
| Long‐term evaluation of early‐enamel lesions treated with novel experimental tricalcium silicate paste: A 2‐year randomized clinical trial Hamdi 2022 · Hamdi Kareem, Hamama Hamdi H., et al. · Journal of Esthetic and Restorative Dentistry DOI:10.1111/jerd.12941 | 2022 | 1 | none stated | not extracted yet |
| Association of Sleep-Time Feeding Practices with Early Childhood Caries: A Case-Control Study Ganesh 2022 · Ganesh Akila, Muthu M.S., et al. · Caries Research DOI:10.1159/000527035 | 2022 | 1 | none stated | not extracted yet |
| Early childhood caries management using fluoride varnish and neutral fluoride gel: a randomized clinical trial de Sousa 2022 · SOUSA Geovanna Peres de, LIMA Cacilda Castelo Branco, et al. · Brazilian Oral Research DOI:10.1590/1807-3107bor-2022.vol36.0099 | 2022 | 1 | none stated | not extracted yet |
| Prevalence of early childhood caries and associated factors among a group of preschool children in El-Gharbia Governorate Mahmoud Abdallah et al. 2022 · Mahmoud Abdallah Samaa W. S., El Hendawy Fatma A. E., et al. · Tanta Dental Journal DOI:10.4103/tdj.tdj_12_22 | 2022 | 1 | 1 | not extracted yet |
| Therapeutic effect of a novel bioactive glass-ceramics on early caries lesions: a single-center, randomized controlled clinical trial. Guo 2022 · Guo Xiangyu, Li Xue, et al. · Clinical oral investigations PMID:34036434 | 2022 | 1 | none stated | not extracted yet |
| Trajectories of Sugar Consumption and Dental Caries in Early Childhood. Echeverria et al. 2022 · Echeverria M S, Schuch H S, et al. · Journal of dental research PMID:35114848 | 2022 | 1 | 1 | not extracted yet |
| Dental Consequences of Vitamin D Deficiency during Pregnancy and Early Infancy-An Observational Study. Beckett 2022 · Beckett Deanna M, Broadbent Jonathan M, et al. · International journal of environmental research and public health PMID:35206117 | 2022 | 1 | none stated | not extracted yet |
| Early Childhood Caries Prevalence and Associated Risk Factors in Monastir, Tunisia: A Cross-Sectional Study. Chouchene et al. 2022 · Chouchene Farah, Masmoudi Fatma, et al. · Frontiers in public health PMID:35284400 | 2022 | 1 | 1 | not extracted yet |
| Exploring the Relationship between Salivary Levels of TNF-α, Lactobacillus acidophilus, Lactobacillus gasseri, Obesity, and Caries in Early Childhood. Leme 2022 · Leme Lúcia Aparecida Federighi Pereira, Rizzardi Karina Ferreira, et al. · Pathogens (Basel, Switzerland) PMID:35631100 | 2022 | 1 | none stated | not extracted yet |
| Taxonomic and functional alterations in the salivary microbiota of children with and without severe early childhood caries (S-ECC) at the age of 3. Tang et al. 2022 · Tang Zhe, Xu Wenyi, et al. · PeerJ PMID:35669952 | 2022 | 1 | none stated | not extracted yet |
| Effect of a Short-Term Intervention with Lactobacillus salivarius Probiotic on Early Childhood Caries-An Open Label Randomized Controlled Trial. Staszczyk et al. 2022 · Staszczyk Małgorzata, Jamka-Kasprzyk Małgorzata, et al. · International journal of environmental research and public health PMID:36231747 | 2022 | 1 | 1 | not extracted yet |
| Impact of a Prenatal Vitamin D Supplementation Program on Vitamin D Deficiency, Rickets and Early Childhood Caries in an Alaska Native Population. Singleton 2022 · Singleton Rosalyn J, Day Gretchen M, et al. · Nutrients PMID:36235588 | 2022 | 1 | 1 | not extracted yet |
| Prediction model for early childhood caries risk based on behavioral determinants using a machine learning algorithm. Qu (2022) · Qu Xing, Zhang Chao, et al. · Computer methods and programs in biomedicine PMID:36384058 | 2022 | 1 | 1 | not extracted yet |
| Caesarean delivery and early childhood caries: Estimation with marginal structural models in Brazilian pre‐schoolers Ladeira LLC 2021 · Ladeira Lorena Lúcia Costa, Martins Sarah Pereira, et al. · Community Dentistry and Oral Epidemiology DOI:10.1111/cdoe.12634 | 2021 | 1 | 1 | not extracted yet |