Primary study · included by 2 reviews

Investigation of Interaction between Vitamin D Receptor Gene Polymorphisms and Environmental Factors in Early Childhood Caries in Chinese Children.

Qin 2019 · Qin Xiurong, Shao Linqin, Zhang Lixia, et al. · BioMed research international · 2019

PubMed 31930121 doi:10.1155/2019/4315839Journal Article

Trial PICO

Not extracted yet. Trial-level population, intervention, comparator, outcomes and design will appear here after the trial extraction run. Until then, the reviews below describe the study.

Results

Not extracted yet. Per-trial results (events, means, effect and weight as each review's forest plot reports them) will appear here after the trial extraction run.

Included by

Association Between the TaqI (rs731236 T>C) Gene Polymorphism and Dental Caries Risk: A Meta-analysis.

Non-Cochrane · aetiology · 2021 · cited as Qin 2019 · Table 2; Reference 20

The review does not say which of its outcomes this study informs.

Association of vitamin D receptor gene polymorphisms with caries risk in children: a systematic review and meta-analysis.

Non-Cochrane · aetiology · 2024 · cited as Qin 2019 · Table 5; Table 6 (TaqI(rs731236))

Outcome this study informs	Pooled effect	Evidence	Certainty
Dental caries TT genotype vs TC+CC genotypes · Recessive model (TT vs TC+CC)	OR 1.49 [0.97, 2.27]	NR	Ungraded
Dental caries TT+TC genotypes vs CC genotype · Dominant model (TT+TC vs CC)	OR 0.84 [0.50, 1.39]	NR	Ungraded
Dental caries TT+TC genotypes vs CC genotype · Dominant model (TT+TC vs CC)	OR 1.25 [0.08, 20.04]	NR	Ungraded
Dental caries TT+TC genotypes vs CC genotype · Dominant model (TT+TC vs CC)	OR 0.70 [0.47, 1.05]	NR	Ungraded
Dental caries G allele vs A allele · Allelic model (G vs A)	OR 1.56 [0.76, 3.24]	4 studies · 1741 participants	Ungraded
Dental caries CC genotype vs CA+AA genotypes · Recessive model (CC vs CA+AA)	OR 0.87 [0.70, 1.09]	3 studies · 1327 participants	Ungraded
Dental caries T allele vs C allele · Allelic model (T vs C)	OR 0.90 [0.54, 1.49]	NR	Ungraded
Dental caries C allele vs T allele · Allelic model (C vs T)	OR 1.33 [1.03, 1.71]	3 studies · 1329 participants	Ungraded
Dental caries CC+CT genotypes vs TT genotype · Dominant model (CC+CT vs TT)	OR 1.87 [1.15, 3.04]	3 studies · 1329 participants	Ungraded
Dental caries TT genotype vs TC+CC genotypes · Recessive model (TT vs TC+CC)	OR 1.36 [0.89, 2.08]	NR	Ungraded
Dental caries TT+CC (homozygous) genotypes vs TC (heterozygous) genotype · Over-dominant model (TT+CC vs TC)	OR 1.52 [1.10, 2.10]	NR	Ungraded
Dental caries T allele vs C allele · Allelic model (T vs C)	OR 0.79 [0.60, 1.04]	NR	Ungraded
Dental caries CC+CA genotypes vs AA genotype · Dominant model (CC+CA vs AA)	OR 0.91 [0.55, 1.50]	3 studies · 1327 participants	Ungraded
Dental caries Cdx-2(rs11568820) A allele / genotype vs G allele / reference genotype · Not meta-analyzed (single study)	Cdx-2(rs11568820) was reported by only one study (Qin 2019; 303 caries, 245 caries-free) and was therefore not subjected to meta-analysis (Results 'Meta-analysis'; Table 6).	1 study · 548 participants	Ungraded
Dental caries T allele vs C allele · Allelic model (T vs C)	OR 1.01 [0.83, 1.21]	6 studies · 1986 participants	Ungraded
Dental caries T allele vs C allele · Allelic model (T vs C)	OR 0.98 [0.65, 1.50]	NR	Ungraded
Dental caries T allele vs C allele · Allelic model (T vs C)	OR 0.80 [0.55, 1.15]	NR	Ungraded
Dental caries TT+TC genotypes vs CC genotype · Dominant model (TT+TC vs CC)	OR 0.87 [0.47, 1.61]	NR	Ungraded
Dental caries GG genotype vs GA+AA genotypes · Recessive model (GG vs GA+AA), Zhang 2006 removed	OR 0.86 [0.48, 1.54]	3 studies · 1329 participants	Ungraded
Dental caries AA+GG (homozygous) genotypes vs GA (heterozygous) genotype · Over-dominant model (AA+GG vs GA), Zhang 2006 removed	OR 0.85 [0.48, 1.49]	3 studies · 1329 participants	Ungraded
Dental caries TT+TC genotypes vs CC genotype · Dominant model (TT+TC vs CC)	OR 0.75 [0.54, 1.05]	5 studies · 1606 participants	Ungraded
Dental caries TT+CC (homozygous) genotypes vs TC (heterozygous) genotype · Over-dominant model (TT+CC vs TC)	OR 1.49 [0.97, 2.28]	NR	Ungraded
Dental caries TT+TC genotypes vs CC genotype · Dominant model (TT+TC vs CC)	OR 0.69 [0.44, 1.07]	NR	Ungraded
Dental caries TT+CC (homozygous) genotypes vs TC (heterozygous) genotype · Over-dominant model (TT+CC vs TC)	OR 1.38 [1.02, 1.87]	NR	Ungraded
Dental caries CC genotype vs CT+TT genotypes · Recessive model (CC vs CT+TT)	OR 1.23 [0.97, 1.55]	3 studies · 1329 participants	Ungraded
Dental caries CC+AA (homozygous) genotypes vs CA (heterozygous) genotype · Over-dominant model (CC+AA vs CA)	OR 0.91 [0.73, 1.14]	3 studies · 1327 participants	Ungraded
Dental caries GG genotype vs GA+AA genotypes · Recessive model (GG vs GA+AA)	OR 0.58 [0.26, 1.30]	4 studies · 1741 participants	Ungraded
Dental caries TT+CC (homozygous) genotypes vs TC (heterozygous) genotype · Over-dominant model (TT+CC vs TC)	OR 1.15 [0.83, 1.60]	NR	Ungraded
Dental caries TT genotype vs TC+CC genotypes · Recessive model (TT vs TC+CC)	OR 1.05 [0.56, 1.98]	NR	Ungraded
Dental caries T allele vs C allele · Allelic model (T vs C)	OR 1.45 [0.96, 2.18]	NR	Ungraded
Dental caries T allele vs C allele · Allelic model (T vs C)	OR 1.24 [0.96, 1.60]	NR	Ungraded
Dental caries TT+CC (homozygous) genotypes vs TC (heterozygous) genotype · Over-dominant model (TT+CC vs TC)	OR 1.48 [1.07, 2.03]	NR	Ungraded
Dental caries TT genotype vs TC+CC genotypes · Recessive model (TT vs TC+CC)	OR 0.83 [0.54, 1.29]	NR	Ungraded
Dental caries TT genotype vs TC+CC genotypes · Recessive model (TT vs TC+CC)	OR 1.21 [0.93, 1.56]	5 studies · 1586 participants	Ungraded
Dental caries TT+CC (homozygous) genotypes vs TC (heterozygous) genotype · Over-dominant model (TT+CC vs TC)	OR 1.33 [1.06, 1.67]	6 studies · 1986 participants	Ungraded
Dental caries TT genotype vs TC+CC genotypes · Recessive model (TT vs TC+CC)	OR 0.73 [0.43, 1.24]	NR	Ungraded
Dental caries TT+CC (homozygous) genotypes vs TC (heterozygous) genotype · Over-dominant model (TT+CC vs TC)	OR 0.85 [0.50, 1.45]	NR	Ungraded
Dental caries TT genotype vs TC+CC genotypes · Recessive model (TT vs TC+CC)	OR 1.16 [0.85, 1.60]	NR	Ungraded
Dental caries C allele vs A allele · Allelic model (C vs A)	OR 0.89 [0.70, 1.14]	3 studies · 1327 participants	Ungraded
Dental caries AA+GG (homozygous) genotypes vs GA (heterozygous) genotype · Over-dominant model (AA+GG vs GA)	OR 0.60 [0.28, 1.25]	4 studies · 1741 participants	Ungraded
Dental caries TT+TC genotypes vs CC genotype · Dominant model (TT+TC vs CC)	OR 0.81 [0.44, 1.51]	NR	Ungraded
Dental caries TT+TC genotypes vs CC genotype · Dominant model (TT+TC vs CC)	OR 0.72 [0.48, 1.07]	NR	Ungraded
Dental caries TT genotype vs TC+CC genotypes · Recessive model (TT vs TC+CC)	OR 1.49 [0.97, 2.27]	NR	Ungraded
Dental caries CC+TT (homozygous) genotypes vs CT (heterozygous) genotype · Over-dominant model (CC+TT vs CT)	OR 0.83 [0.67, 1.04]	3 studies · 1329 participants	Ungraded
Dental caries TT+CC (homozygous) genotypes vs TC (heterozygous) genotype · Over-dominant model (TT+CC vs TC)	OR 1.26 [0.88, 1.80]	NR	Ungraded
Dental caries T allele vs C allele · Allelic model (T vs C)	OR 1.00 [0.72, 1.39]	NR	Ungraded

2 including reviews in total.