Cochrane Review Group

Infectious Diseases

135 systematic reviews in Infectious Diseases ask 1,518 questions. 8.9% have no studies to answer them, 23.1% rest on very low certainty evidence and 30.5% reach moderate or high certainty.

Reviews
135
Questions
1,518
current versions
No studies
8.9%
Moderate or high
30.5%
No studies 135 · 8.9%Ungraded 150 · 9.9%Very low 350 · 23.1%Low 420 · 27.7%Moderate 321 · 21.1%High 142 · 9.4%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Favipiravir vs no treatment, supportive treatment, or other antiviral treatment
All‐cause mortality – at 28 to 30 days, or in‐hospital · people with confirmed COVID‐19
Favipiravir for treating COVID‐19 (2024) · Cochrane
RR 0.84 [0.49, 1.46]11 studies · 3459 participantsVery low
Favipiravir vs no treatment, supportive treatment, or other antiviral treatment
Progression to invasive mechanical ventilation · people with confirmed COVID‐19
Favipiravir for treating COVID‐19 (2024) · Cochrane
RR 0.86 [0.68, 1.09]8 studies · 1383 participantsVery low
Favipiravir vs no treatment, supportive treatment, or other antiviral treatment
Time to clinical improvement (defined as time to a 2‐point reduction in patients’ admission status on WHO’s ordinal scale) · people with confirmed COVID‐19
Favipiravir for treating COVID‐19 (2024) · Cochrane
HR 1.13 [0.69, 1.83]4 studies · 721 participantsVery low
wMel‐Wolbachia infected Aedes aegypti deployments vs no deployments
Virologically confirmed dengue case incidence (any severity, any phenotype) · children and adults at risk of dengue infection
Wolbachia ‐carrying Aedes mosquitoes for preventing dengue infection (2024) · Cochrane
no estimate extractedNRNo studies
wMel‐Wolbachia infected Aedes aegypti deployments vs no deployments
Prevalence of dengue RNA in the mosquito population · children and adults at risk of dengue infection
Wolbachia ‐carrying Aedes mosquitoes for preventing dengue infection (2024) · Cochrane
no estimate extractedNRNo studies
wMel‐Wolbachia infected Aedes aegypti deployments vs no deployments
Mosquito density (for population suppression strategy) · children and adults at risk of dengue infection
Wolbachia ‐carrying Aedes mosquitoes for preventing dengue infection (2024) · Cochrane
no estimate extractedNRNo studies
wMel‐Wolbachia infected Aedes aegypti deployments vs no deployments
Prevalence of Wolbachia‐carrying mosquitoes (for population replacement strategy) · children and adults at risk of dengue infection
Wolbachia ‐carrying Aedes mosquitoes for preventing dengue infection (2024) · Cochrane
no estimate extractedNRNo studies
wMel‐Wolbachia infected Aedes aegypti deployments vs no deployments
Adverse events potentially related to Wolbachia‐carrying Aedes deployments · children and adults at risk of dengue infection
Wolbachia ‐carrying Aedes mosquitoes for preventing dengue infection (2024) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Cluster‐RCTs · adults and children
Interventions to improve sanitation for preventing diarrhoea (2023) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Cluster‐RCTs · adults and children
Interventions to improve sanitation for preventing diarrhoea (2023) · Cochrane
no estimate extractedNRNo studies
Intervention NR
NRCTs · adults and children
Interventions to improve sanitation for preventing diarrhoea (2023) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Cluster‐RCTs · adults and children
Interventions to improve sanitation for preventing diarrhoea (2023) · Cochrane
no estimate extractedNRNo studies

Reviews 135

Intermittent preventive treatment for malaria in children living in areas with seasonal transmission

Meremikwu, MM, Donegan, S, et al. · Cochrane Database of Systematic Reviews · 2012
CochraneSoF table
6 questions

Artesunate versus quinine for treating severe malaria

Sinclair, D, Donegan, S, et al. · Cochrane Database of Systematic Reviews · 2012
CochraneSoF table
10 questions

Patient education and counselling for promoting adherence to treatment for tuberculosis

M'Imunya, JM, Kredo, T, et al. · Cochrane Database of Systematic Reviews · 2012
CochraneSoF table
2 questions

Antibiotics for treating human brucellosis

Yousefi‐Nooraie, R, Mortaz‐Hejri, S, et al. · Cochrane Database of Systematic Reviews · 2012
CochraneSoF table
6 questions

Drugs for treating giardiasis

Granados, CE, Reveiz, L, et al. · Cochrane Database of Systematic Reviews · 2012
CochraneSoF table
14 questions

Oral rehydration salt solution for treating cholera: ≤ 270 mOsm/L solutions vs ≥ 310 mOsm/L solutions

Musekiwa, A, Volmink, J · Cochrane Database of Systematic Reviews · 2011
CochraneSoF table
14 questions

Mannitol and other osmotic diuretics as adjuncts for treating cerebral malaria

Okoromah, CAN, Afolabi, BB, et al. · Cochrane Database of Systematic Reviews · 2011
CochraneSoF table
7 questions

Intermittent preventive treatment regimens for malaria in HIV‐positive pregnant women

Mathanga, DP, Uthman, OA, et al. · Cochrane Database of Systematic Reviews · 2011
CochraneSoF table
10 questions

Oral vaccines for preventing cholera

Sinclair, D, Abba, K, et al. · Cochrane Database of Systematic Reviews · 2011
CochraneSoF table
3 questions

Antibiotic therapy for Shigella dysentery

Christopher, PRH, David, KV, et al. · Cochrane Database of Systematic Reviews · 2010
CochraneSoF table
34 questions