Cochrane Review Group
Infectious Diseases
135 systematic reviews in Infectious Diseases ask 1,518 questions. 8.9% have no studies to answer them, 23.1% rest on very low certainty evidence and 30.5% reach moderate or high certainty.
Reviews
135
Questions
1,518
current versions
No studies
8.9%
Moderate or high
30.5%
No studies 135 · 8.9%Ungraded 150 · 9.9%Very low 350 · 23.1%Low 420 · 27.7%Moderate 321 · 21.1%High 142 · 9.4%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Thinnest evidence
All no studies and very low questions| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Favipiravir vs no treatment, supportive treatment, or other antiviral treatment All‐cause mortality – at 28 to 30 days, or in‐hospital · people with confirmed COVID‐19 Favipiravir for treating COVID‐19 (2024) · Cochrane | RR 0.84 [0.49, 1.46] | 11 studies · 3459 participants | Very low |
Favipiravir vs no treatment, supportive treatment, or other antiviral treatment Progression to invasive mechanical ventilation · people with confirmed COVID‐19 Favipiravir for treating COVID‐19 (2024) · Cochrane | RR 0.86 [0.68, 1.09] | 8 studies · 1383 participants | Very low |
Favipiravir vs no treatment, supportive treatment, or other antiviral treatment Time to clinical improvement (defined as time to a 2‐point reduction in patients’ admission status on WHO’s ordinal scale) · people with confirmed COVID‐19 Favipiravir for treating COVID‐19 (2024) · Cochrane | HR 1.13 [0.69, 1.83] | 4 studies · 721 participants | Very low |
wMel‐Wolbachia infected Aedes aegypti deployments vs no deployments Virologically confirmed dengue case incidence (any severity, any phenotype) · children and adults at risk of dengue infection Wolbachia ‐carrying Aedes mosquitoes for preventing dengue infection (2024) · Cochrane | no estimate extracted | NR | No studies |
wMel‐Wolbachia infected Aedes aegypti deployments vs no deployments Prevalence of dengue RNA in the mosquito population · children and adults at risk of dengue infection Wolbachia ‐carrying Aedes mosquitoes for preventing dengue infection (2024) · Cochrane | no estimate extracted | NR | No studies |
wMel‐Wolbachia infected Aedes aegypti deployments vs no deployments Mosquito density (for population suppression strategy) · children and adults at risk of dengue infection Wolbachia ‐carrying Aedes mosquitoes for preventing dengue infection (2024) · Cochrane | no estimate extracted | NR | No studies |
wMel‐Wolbachia infected Aedes aegypti deployments vs no deployments Prevalence of Wolbachia‐carrying mosquitoes (for population replacement strategy) · children and adults at risk of dengue infection Wolbachia ‐carrying Aedes mosquitoes for preventing dengue infection (2024) · Cochrane | no estimate extracted | NR | No studies |
wMel‐Wolbachia infected Aedes aegypti deployments vs no deployments Adverse events potentially related to Wolbachia‐carrying Aedes deployments · children and adults at risk of dengue infection Wolbachia ‐carrying Aedes mosquitoes for preventing dengue infection (2024) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Cluster‐RCTs · adults and children Interventions to improve sanitation for preventing diarrhoea (2023) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Cluster‐RCTs · adults and children Interventions to improve sanitation for preventing diarrhoea (2023) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR NRCTs · adults and children Interventions to improve sanitation for preventing diarrhoea (2023) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Cluster‐RCTs · adults and children Interventions to improve sanitation for preventing diarrhoea (2023) · Cochrane | no estimate extracted | NR | No studies |
Reviews 135
Intermittent preventive treatment for malaria in children living in areas with seasonal transmission
CochraneSoF table
6 questions
Artesunate versus quinine for treating severe malaria
CochraneSoF table
10 questions
Patient education and counselling for promoting adherence to treatment for tuberculosis
CochraneSoF table
2 questions
Antibiotics for treating human brucellosis
CochraneSoF table
6 questions
Drugs for treating giardiasis
CochraneSoF table
14 questions
Oral rehydration salt solution for treating cholera: ≤ 270 mOsm/L solutions vs ≥ 310 mOsm/L solutions
CochraneSoF table
14 questions
Mannitol and other osmotic diuretics as adjuncts for treating cerebral malaria
CochraneSoF table
7 questions
Intermittent preventive treatment regimens for malaria in HIV‐positive pregnant women
CochraneSoF table
10 questions
Oral vaccines for preventing cholera
CochraneSoF table
3 questions
Antibiotic therapy for Shigella dysentery
CochraneSoF table
34 questions