Cochrane · systematic review · CD007787
Drugs for treating giardiasis
Granados, CE, Reveiz, L, Uribe, LG, et al. · Cochrane Database of Systematic Reviews · 2012 · Cochrane Library
Infectious DiseasesAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
14
current version
GRADE rated
11
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 3 · 21.4%Very low 7 · 50%Low 1 · 7.1%Moderate 3 · 21.4%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Comparison
Population: People with giardiasis infection
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Parasitological cure ( | RR 0.99 [0.95, 1.03] | 10 studies · 932 participants | Moderate Downgraded: risk of bias |
Clinical improvement ( | RR 0.98 [0.93, 1.04] | 5 studies · 483 participants | Moderate Downgraded: risk of bias |
Gastrointestinal side effects ( | RR 0.29 [0.13, 0.63] | 8 studies · 717 participants | Moderate Downgraded: risk of bias |
Neurological side effects ( | RR 0.34 [0.18, 0.64] | 5 studies · 453 participants | Low Downgraded: risk of bias, imprecision |
Comparison
Population: People with giardiasis infection
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Parasitological cure ( | RR 0.58 [0.32, 1.06] | 5 studies · 142 participants | Very low Downgraded: risk of bias, imprecision |
Clinical improvement | no estimate extracted | 0 studies · 0 participants | Ungraded |
Side effects: nausea/vomiting | RR 0.32 [0.05, 1.9] | 3 studies · 100 participants | Very low Downgraded: risk of bias, imprecision |
Side effects: headache | RR 0.24 [0.03, 2.06] | 2 studies · 74 participants | Very low Downgraded: risk of bias, imprecision |
Serious adverse events | no estimate extracted | 5 studies · 142 participants | Ungraded |
Comparison
Population: People with giardiasis infection
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Parasitological cure ( | RR 1.23 [0.87, 1.73] | 3 studies · 179 participants | Very low Downgraded: risk of bias, imprecision |
Clinical improvement ( | RR 1.15 [1, 1.32] | 3 studies · 179 participants | Very low Downgraded: risk of bias, imprecision |
Gastrointestinal side effects ( | RR 0.58 [0.21, 1.62] | 3 studies · 179 participants | Very low Downgraded: risk of bias, imprecision |
Neurological side effects ( | RR 1.3 [0.29, 5.92] | 2 studies · 138 participants | Very low Downgraded: risk of bias, imprecision |
Serious adverse events | no estimate extracted | 3 studies · 179 participants | Ungraded |