Cochrane · systematic review · CD006689
Intermittent preventive treatment regimens for malaria in HIV‐positive pregnant women
Mathanga, DP, Uthman, OA, Chinkhumba, J · Cochrane Database of Systematic Reviews · 2011 · Cochrane Library
Infectious DiseasesAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
10
current version
GRADE rated
10
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 6 · 60%Low 4 · 40%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Primigravidae and secundigravidae
Population: HIV‐positive pregnant women living
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Maternal parasitaemia (at delivery) | RR 0.25 [0.14, 0.43] | 2 studies · 463 participants | Low Downgraded: risk of bias, imprecision |
Placental parasitaemia (at delivery) | RR 0.38 [0.21, 0.7] | 2 studies · 459 participants | Low Downgraded: risk of bias, imprecision |
Maternal anaemia (Hb < 11 g/dL at delivery) | RR 0.93 [0.72, 1.2] | 2 studies · 447 participants | Low Downgraded: risk of bias, imprecision |
Low birth weight (< 2.5 kg) | RR 0.8 [0.52, 1.23] | 2 studies · 469 participants | Low Downgraded: risk of bias, imprecision |
Neonatal mortality | RR 0.29 [0.08, 1.05] | 1 study · 253 participants | Very low Downgraded: risk of bias, imprecision |
Multigravidae (greater than 2 pregnancies)
Population: HIV‐positive pregnant women
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Maternal parasitaemia (at delivery) | RR 0.94 [0.06, 14.75] | 1 study · 159 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Placental parasitaemia (at delivery) | RR 1.87 [0.17, 20.23] | 1 study · 153 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Maternal anaemia (Hb < 11 g/dL at delivery) | RR 0.98 [0.69, 1.4] | 1 study · 157 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Low birth weight (< 2.5 kg) | RR 1.41 [0.57, 3.51] | 1 study · 155 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Neonatal mortality | no estimate extracted | NR | Very low Downgraded: risk of bias, imprecision, indirectness |