Cochrane · systematic review · CD004615
Mannitol and other osmotic diuretics as adjuncts for treating cerebral malaria
Okoromah, CAN, Afolabi, BB, Wall, ECB · Cochrane Database of Systematic Reviews · 2011 · Cochrane Library
Infectious DiseasesAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
3
No studies
4
Included studies
NR
No studies 4 · 57.1%Ungraded 0 · 0%Very low 0 · 0%Low 3 · 42.9%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Comparison
Population: Children aged 6‐60 months with cerebral malaria
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Death | RR 0.81 | 1 study · 156 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Major neurological sequelae | no estimate extracted | NR | No studies |
Coma recovery time | no estimate extracted | 1 study · 156 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Time to hospital discharge | no estimate extracted | NR | No studies |
Need for ventilation | no estimate extracted | NR | No studies |
Need for cardiopulmonary resuscitation | no estimate extracted | NR | No studies |
Adverse events | no estimate extracted | 1 study · 156 participants | Low Downgraded: imprecision, inconsistency, indirectness |