Food intake · Children and adolescents (general population, aged under 20 years)
Food marketing was associated with a significant increase in children's food intake (pooled SMD, 0.25; combined RCT and nonrandomized evidence).
3 findings from 1 review
DMFS (decayed, missing, filled surfaces) increment, occlusal surfaces · Schoolchildren aged 6-12 years with sound occlusal surfaces of the first permanent molars
Pit and fissure sealant and fluoride varnish showed no statistically significant difference in DMFS increment at 24 months (SMD -0.13, 95% CI -0.67 to 0.40; I2=92%; not GRADE-rated).
1 finding from 1 review
Overweight/obesity risk · Healthy, term-born, normal-birth-weight infants aged 4-24 months (breastfed and/or formula-fed) in Western industrialized countries
Responsive complementary feeding probably reduces the risk of overweight/obesity versus other feeding models (RR 0.41, 95% CI 0.24 to 0.71; moderate certainty).
1 finding from 1 review
Intervention not reported
Adverse events
1 finding from 1 review
Post-treatment pain within 1 week (from first session) · People aged 10 years or above requiring root canal treatment; permanent teeth with completely formed apex and without internal resorption
Single-visit root canal treatment probably leads to higher post-treatment pain within 1 week (from first session) compared with multiple-visit root canal treatment (two or more visits) (moderate certainty).
1 finding from 1 review
Restoration survival · Children with decayed primary molar teeth
Multi-surface ART restorations had a reported survival rate of 73% at 1 year.
4 findings from 1 review
Survival rate 73
9 studies
GRADE not reported
Survival rate 95
9 studies
GRADE not reported
Survival rate 59
9 studies
GRADE not reported
Show 1 more finding
Survival rate 91
9 studies
GRADE not reported
Restoration failure · Children with carious primary teeth after vital or non-vital pulp therapy
In one RCT, composite strip crowns with composite posts had an annual failure rate of 2.3% after 1 year.
1 finding from 1 review
Dental caries prevalence · 12-year-old children (permanent dentition) in Africa
Pooled caries prevalence in Uganda was 0.27 (95% CI 0.126 to 0.418; 3 article(s); not GRADE-rated).
23 findings from 1 review
Prevalence 0.27 [0.126, 0.418]
3 studies
GRADE not reported
Prevalence 0.329 [0.111, 0.548]
3 studies
GRADE not reported
Prevalence 0.282 [0.227, 0.337]
13 studies
GRADE not reported
Show 20 more findings
Prevalence 0.13 [0.106, 0.163]
2 studies
GRADE not reported
Prevalence 0.78 [0.724, 0.831]
1 study
GRADE not reported
Prevalence 0.34 [0.276, 0.401]
5 studies
GRADE not reported
Prevalence 0.48 [0.45, 0.514]
1 study
GRADE not reported
Prevalence 0.391 [0.305, 0.477]
10 studies
GRADE not reported
Prevalence 0.36 [0.294, 0.417]
25 studies · 18080 participants
GRADE not reported
Prevalence 0.314 [0.186, 0.443]
10 studies
GRADE not reported
Prevalence 0.30 [0.239, 0.375]
1 study
GRADE not reported
Prevalence 0.49 [0.42, 0.568]
1 study
GRADE not reported
Prevalence 0.73 [0.694, 0.759]
1 study
GRADE not reported
Prevalence 0.31 [0.279, 0.333]
1 study
GRADE not reported
Prevalence 0.346 [0.085, 0.606]
3 studies
GRADE not reported
Prevalence 0.29 [0.247, 0.326]
1 study
GRADE not reported
Prevalence 0.33 [0.066, 0.584]
3 studies
GRADE not reported
Prevalence 0.574 [0.427, 0.721]
5 studies
GRADE not reported
Prevalence 0.34 [0.299, 0.376]
2 studies
GRADE not reported
Prevalence 0.59 [0.523, 0.654]
1 study
GRADE not reported
Prevalence 0.11 [0.045, 0.26]
1 study
GRADE not reported
Prevalence 0.403 [0.233, 0.574]
7 studies
GRADE not reported
Prevalence 0.19 [0.168, 0.214]
1 study
GRADE not reported
Dental caries prevalence · European adolescents aged 15 years
Pooled caries prevalence was 0.77 (I² = 97.9%).
1 finding from 1 review
Treatment failure (annual failure rate) · Children with previously unrestored, vital carious lesions in primary teeth (no pulp therapy); aged 1.5-11 years
RMGIC had an annual failure rate of 1.9-16.9% (4 RCTs), lower than amalgam and similar to compomer/composite; low quality of evidence (ungraded).
1 finding from 1 review
Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them
Chlorhexidine (CHX) led to lower reduction in level of contamination by particles >5 um (droplets) at… compared with essential oils/herbal mouthwash; GRADE not reported.
4 findings from 1 review
MD -44.1 [-59.12, -29.08]
1 study · 20 participants
GRADE not reported
Bay 1993 compared 0.12% CHX with essential oil mouthwash C (Listerine) at pharynx level (Andersen's level 2), which was considered patient level and hence was not analysed. No pooled estimate or GRADE rating.
1 study
GRADE not reported
MD -12.21 [-15.58, -8.83]
3 studies · 76 participants
Low
Show 1 more finding
Dental caries prevalence and severity · Children and adolescents (<18 years) living with HIV (CLWH)
No significant difference in dental caries/severity between ART regimens (very low certainty).
1 finding from 1 review
Enamel caries proportion · European adolescents aged 15 years
Pooled enamel caries proportion was 0.72 (I² = 99.8%).
1 finding from 1 review
Kaposi's sarcoma (WHO clinical stage 4) · Children or adolescents
No eligible studies reported Kaposi's sarcoma.
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Human permanent teeth with irreversible pulpitis due to carious pulp exposure
Among 6 observational studies, pooled pulpotomy success was 92.6 per 100 (95% CI 0.86-0.96), very low certainty.
4 findings from 1 review
Show 1 more finding
Z score BMI · Healthy, term-born, normal-birth-weight infants aged 4-24 months (breastfed and/or formula-fed) in Western industrialized countries
In one RCT, responsive complementary feeding lowered BMIz at 13 months versus control (0.23 vs 0.42, p=0.01; low certainty).
1 finding from 1 review
Risk of overweight and obesity after 13 mo (RCT, BMIz): DANIELS 2012 - children in the intervention group had a lower BMIz at 13 months than controls (0.23 +/- 0.93 vs 0.42 +/- 0.85; p = 0.01); 698 (1 RCT); Low.
1 study · 698 participants
Low
Overall success (composite of clinical and radiographic success) · Human permanent teeth with irreversible pulpitis due to carious pulp exposure
CEM and calcium hydroxide did not differ significantly in pulpotomy success (indirect comparison); ungraded.
1 finding from 1 review
Adverse events · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
1 finding from 1 review
No adverse events were reported. Six trials (673 participants) reported no adverse events from the use of chlorhexidine gel; one study (Rubio-Palau 2015) reported gastrointestinal discomfort (30, 18%), dizziness (10,…
7 studies
GRADE not reported
Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them
1 finding from 1 review
Salivary immunoglobulin A (SIgA) concentration · Children or adolescents
No significant difference in total salivary IgA between CLWH and healthy controls, though anti-Candida SIgA was higher in HIV groups; narrative only.
1 finding from 1 review
Oral Health Status of Children and Adolescents Living with HIV Undergoing Antiretroviral Therapy: A Systematic Review… 2022 All outcomesCross-sectional (case-control; single time point) · HIV pediatric/ART clinics, AIDS centers, and hospitals in Brazil, India, Saudi Arabia, and West Africa (Cote d'Ivoire, Mali, Senegal)
Pomarico 2009 reported no significant difference in total SIgA among HIV-ART, HIV-HAART, and healthy children, but significantly higher anti-Candida albicans SIgA in the two HIV groups; no effect estimate pooled.
1 study
GRADE not reported