Question · asked by 1 review
Chlorhexidine gel (0.2%, intrasocket) vs placebo or no treatment: Adverse events
- Population
- Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
- Intervention
- Chlorhexidine gel (0.2%, intrasocket)
- Comparison
- placebo or no treatment
- Outcome
- Adverse events
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Chlorhexidine gel (0.2%, intrasocket) vs Placebo or no treatment Adverse events · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars) · Follow-up: median 7 days Local interventions for the management of alveolar osteitis (dry socket) (2022) · Cochrane All outcomes | No adverse events were reported. Six trials (673 participants) reported no adverse events from the use of chlorhexidine gel; one study (Rubio-Palau 2015) reported gastrointestinal discomfort (30, 18%), dizziness (10,… | 7 studies | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Local interventions for the management of alveolar osteitis (dry socket) 2022 · Cochrane All outcomes | 2021-09 | Not listed | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Chlorhexidine gel (0.2%, intrasocket) vs Chlorhexidine mouthrinse · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third… · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.