Gap finder

Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

830 questions in 43 reviews · Orthodontics

current versions
No studies 186 · 22.4%Ungraded 410 · 49.4%Very low 122 · 14.7%Low 79 · 9.5%Moderate 30 · 3.6%High 3 · 0.4%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Anorexia nervosa (as exposure; diagnosed by DSM-III/III-R/IV/V) vs Healthy individuals without anorexia nervosa (age- and sex-matched controls)
Bleeding on probing (BOP) · Patients with anorexia nervosa aged >=12 years (mean age ~18.4; entirely female in reported data), general…
The influence of anorexia nervosa on oral health and related parameters potentially relevant to orthodontic… (2025)
MD 16.57 [12.89, 20.25]2 studies · 326 participantsLow
Fluoride mouthrinse (0.05-0.32% sodium fluoride or amine fluoride) added to daily fluoride toothpaste vs Control: fluoride toothpaste alone, placebo mouthrinse + toothpaste, or non-fluoride (chlorhexidine) mouthrinse + toothpaste
Incidence of initial caries around brackets, aesthetic-zone teeth only · Children, adolescents and adults undergoing fixed (multi-bracket) orthodontic treatment · At debonding (Gorelick index), Aesthetic zone (central and lateral incisors, canines)
Fluoride mouthrinses for prevention of initial caries in orthodontic patients - a systematic review and… (2025)
In two studies, a significant reduction of the incidence of initial caries around orthodontic brackets was reported in the FMR group when only teeth in the 'aesthetic zone' (central and lateral incisors, canines) were…2 studiesUngraded
Anorexia nervosa (as exposure; diagnosed by DSM-III/III-R/IV/V) vs Healthy individuals without anorexia nervosa (age- and sex-matched controls)
Stimulated salivary flow rate · Patients with anorexia nervosa aged >=12 years (mean age ~18.4; entirely female in reported data), general…
The influence of anorexia nervosa on oral health and related parameters potentially relevant to orthodontic… (2025)
Stimulated salivary flow rate significantly lower in anorexic patients (Paszynska 2015 Nov 1.20 vs 1.57 ml/min, p=0.005; Paszynska 2018 0.99 vs 1.45 ml/min, p<0.00001); reported narratively, not meta-analyzed2 studies · 126 participantsUngraded
Anorexia nervosa (as exposure; diagnosed by DSM-III/III-R/IV/V) vs Healthy individuals without anorexia nervosa (age- and sex-matched controls)
Salivary pH · Patients with anorexia nervosa aged >=12 years (mean age ~18.4; entirely female in reported data), general…
The influence of anorexia nervosa on oral health and related parameters potentially relevant to orthodontic… (2025)
MD -0.39 [-0.54, -0.24]3 studies · 180 participantsLow
Fluoride mouthrinse (0.05-0.32% sodium fluoride or amine fluoride) added to daily fluoride toothpaste vs Control: fluoride toothpaste alone, placebo mouthrinse + toothpaste, or non-fluoride (chlorhexidine) mouthrinse + toothpaste
Incidence of proximal (interdental) caries lesions from bitewing radiographs · Children, adolescents and adults undergoing fixed (multi-bracket) orthodontic treatment · At debonding (~23-24 months)
Fluoride mouthrinses for prevention of initial caries in orthodontic patients - a systematic review and… (2025)
In one study assessments of proximal caries incidence were made as well [18]. However, just the data on the incidence of white spot lesions was included in our meta-analysis as different endpoints for the assessments…1 studyUngraded
Anorexia nervosa (as exposure; diagnosed by DSM-III/III-R/IV/V) vs Healthy individuals without anorexia nervosa (age- and sex-matched controls)
Salivary alpha-amylase · Patients with anorexia nervosa aged >=12 years (mean age ~18.4; entirely female in reported data), general…
The influence of anorexia nervosa on oral health and related parameters potentially relevant to orthodontic… (2025)
MD 6.32 [-6.14, 18.79]4 studies · 226 participantsLow
Anorexia nervosa (as exposure; diagnosed by DSM-III/III-R/IV/V) vs Healthy individuals without anorexia nervosa (age- and sex-matched controls)
Unstimulated salivary flow rate · Patients with anorexia nervosa aged >=12 years (mean age ~18.4; entirely female in reported data), general…
The influence of anorexia nervosa on oral health and related parameters potentially relevant to orthodontic… (2025)
MD -0.27 [-0.31, -0.24]4 studies · 316 participantsModerate
Anorexia nervosa (as exposure; diagnosed by DSM-III/III-R/IV/V) vs Healthy individuals without anorexia nervosa (age- and sex-matched controls)
Gingival (marginal) recession · Patients with anorexia nervosa aged >=12 years (mean age ~18.4; entirely female in reported data), general…
The influence of anorexia nervosa on oral health and related parameters potentially relevant to orthodontic… (2025)
Marginal/gingival recession significantly higher in anorexia nervosa patients (Pallier 2.8% vs 0.0%, p<0.01; Touyz 10.2% vs 2.0%, p<0.001); not meta-analyzed2 studies · 136 participantsUngraded
Anorexia nervosa (as exposure; diagnosed by DSM-III/III-R/IV/V) vs Healthy individuals without anorexia nervosa (age- and sex-matched controls)
Dental erosion · Patients with anorexia nervosa aged >=12 years (mean age ~18.4; entirely female in reported data), general…
The influence of anorexia nervosa on oral health and related parameters potentially relevant to orthodontic… (2025)
Significant prevalence of dental erosion in anorexic patients vs controls, though BEWE scores indicated low erosive-wear risk (Mascitti BEWE 5.2+/-4.5; Paszynska 16.2% at BEWE 3-8); not meta-analyzed2 studies · 270 participantsUngraded
Anorexia nervosa (as exposure; diagnosed by DSM-III/III-R/IV/V) vs Healthy individuals without anorexia nervosa (age- and sex-matched controls)
Dental plaque accumulation (plaque index) · Patients with anorexia nervosa aged >=12 years (mean age ~18.4; entirely female in reported data), general…
The influence of anorexia nervosa on oral health and related parameters potentially relevant to orthodontic… (2025)
In 2 of 3 studies anorexic patients had significantly higher plaque accumulation than controls (Pallier 78.8% vs 53.0%, p<0.01; Paszynska 43.8% vs 13.7%, p<0.001; Milosevic 84% vs 72%, NS); not meta-analyzed3 studies · 394 participantsUngraded
Fluoride mouthrinse (0.05-0.32% sodium fluoride or amine fluoride) added to daily fluoride toothpaste vs Control: fluoride toothpaste alone, placebo mouthrinse + toothpaste, or non-fluoride (chlorhexidine) mouthrinse + toothpaste
Incidence of initial enamel caries / white spot lesions adjacent to bracket base (subject level, dichotomized) · Children, adolescents and adults undergoing fixed (multi-bracket) orthodontic treatment · End of intervention (6-26 months) to within 6 weeks after debonding
Fluoride mouthrinses for prevention of initial caries in orthodontic patients - a systematic review and… (2025)
RD -0.07 [-0.14, -0.01]5 studies · 491 participantsUngraded
Fluoride mouthrinse (0.05-0.32% sodium fluoride or amine fluoride) added to daily fluoride toothpaste vs Control: fluoride toothpaste alone, placebo mouthrinse + toothpaste, or non-fluoride (chlorhexidine) mouthrinse + toothpaste
Adverse effects / harms (side effects) · Children, adolescents and adults undergoing fixed (multi-bracket) orthodontic treatment · During treatment
Fluoride mouthrinses for prevention of initial caries in orthodontic patients - a systematic review and… (2025)
No side- or adverse effects were reported in any of the included reports.7 studies · 704 participantsUngraded
Anorexia nervosa (as exposure; diagnosed by DSM-III/III-R/IV/V) vs Healthy individuals without anorexia nervosa (age- and sex-matched controls)
Caries experience (DMFT index) · Patients with anorexia nervosa aged >=12 years (mean age ~18.4; entirely female in reported data), general…
The influence of anorexia nervosa on oral health and related parameters potentially relevant to orthodontic… (2025)
MD 2.00 [0.87, 3.13]4 studies · 406 participantsLow
Experimental orthodontic composite containing nano-hydroxyapatite (n-HAP) vs Conventional/control orthodontic adhesive (e.g., Transbond XT) or negative control
Superficial surface (enamel) mineralization (surface microhardness) · Human enamel specimens around orthodontic brackets (in vitro) · pH cycling 28 days, Overall
Remineralization and anti-demineralization effect of orthodontic adhesives on enamel surrounding orthodontic… (2024)
A study using an orthodontic composite containing nano-hydroxyapatite showed statistically significant remineralization compared with control orthodontic adhesives [34].1 studyUngraded
ACP light-cure adhesive vs Control Transbond XT adhesive
Enamel demineralization score · Patients undergoing fixed orthodontic treatment · 1 month after bonding
Can Orthodontic Adhesive Systems Inhibit the Formation and Development of White Spot Lesions During Fixed… (2024)
At T1, the control group had an average demineralization score of 3.39 (±1.29), whereas the ACP group had a notably lower average score of 2.58 (±1.11) (p-value of 0.000).1 study · 26 participantsUngraded
Superelastic NiTi arch wire vs Multistrand stainless steel arch wire
Root resorption · People receiving orthodontic treatment with fixed appliances (upper and/or lower full arch)
Initial arch wires used in orthodontic treatment with fixed appliances (2024) · Cochrane
Root resorption: not reported0 studiesNo studies
Thermoelastic copper NiTi (CuNiTi) arch wire vs Conventional NiTi arch wire
Time to next/working arch wire · People receiving orthodontic treatment with fixed appliances (upper and/or lower full arch)
Initial arch wires used in orthodontic treatment with fixed appliances (2024) · Cochrane
MD 0.00 [-0.51, 0.51]1 study · 86 participantsUngraded
Facemask (RME) or modified facemask vs Other non-surgical orthodontic treatments (mini maxillary protractor, Pushing Splints, modified tandem, Reverse Forsus, reverse Twin Block, reverse chin cup, tongue appliance, Frankel III)
Perceived need for surgery in adulthood · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)
Orthodontic treatment for prominent lower front teeth (Class III malocclusion) in children (2024) · Cochrane
SoF3: Perceived need for surgery in adulthood - Not measured.0 studiesNo studies
Bone-anchored intermaxillary traction (BAIMT) vs Removable mandibular retractor (RMR)
Overjet · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion) · 1-year follow-up
Orthodontic treatment for prominent lower front teeth (Class III malocclusion) in children (2024) · Cochrane
MD 0.70 [0.25, 1.15]1 study · 38 participantsUngraded
Orthodontic removable traction appliance (ORTA) vs Untreated control (no treatment)
Wits appraisal · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion) · End of treatment
Orthodontic treatment for prominent lower front teeth (Class III malocclusion) in children (2024) · Cochrane
MD 5.96 [4.71, 7.21]1 study · 40 participantsUngraded
Facemask (with frame internal fixation) vs Frankel III functional appliance
Wits appraisal · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion) · End of treatment
Orthodontic treatment for prominent lower front teeth (Class III malocclusion) in children (2024) · Cochrane
MD 0.06 [-0.26, 0.38]1 study · 34 participantsUngraded
Fixed orthodontic treatment with fixed (multibracket) appliances (exposure) vs None (single-group prevalence/incidence estimate)
Incidence of new ICLs (mean number of new lesions per subject) · Patients undergoing fixed orthodontic treatment with fixed (multibracket) appliances, followed for development of new… · During fixed orthodontic treatment (development of new lesions), Overall (random-effects model)
Distribution of initial caries lesions in relation to fixed orthodontic therapy. A systematic review and… (2024)
MEAN 2.29 [1.12, 3.46]5 studies · 208 participantsVery low
One-step adhesive bonding system (GC Ortho Connect) vs Conventional three-step bonding system (3M Transbond XT)
White spot lesion incidence, area, and depth · Patients undergoing fixed orthodontic treatment · 2 and 4 months after treatment start
Can Orthodontic Adhesive Systems Inhibit the Formation and Development of White Spot Lesions During Fixed… (2024)
Group 3 (GC Ortho Connect) showed a significantly higher incidence than both groups (p < 0.001). Group 3 (GC Ortho Connect) also had larger lesion areas and deeper lesions compared to other groups (p < 0.001).1 study · 75 participantsUngraded
Fixed orthodontic treatment with fixed (multibracket) appliances (exposure) vs None (single-group prevalence/incidence estimate)
Prevalence of ICLs (mean number of lesions per subject) · Patients (permanent dentition) during or after fixed orthodontic treatment with fixed (multibracket) appliances · During or after fixed orthodontic treatment (cross-sectional/at debonding), Overall (random-effects model)
Distribution of initial caries lesions in relation to fixed orthodontic therapy. A systematic review and… (2024)
MEAN 2.24 [1.79, 2.70]6 studies · 484 participantsVery low
Commercial fluoride-releasing RMGIC orthodontic adhesive (Fuji Ortho LC) vs Conventional non-fluoride control orthodontic adhesive (e.g., Transbond XT)
Fluoride ion release · Human enamel specimens around orthodontic brackets (in vitro) · up to 6 months, Overall
Remineralization and anti-demineralization effect of orthodontic adhesives on enamel surrounding orthodontic… (2024)
One study reported significant fluoride release from the commercial RMGIC Fuji Ortho LC up to 6 months [14].1 studyUngraded
Mandibular headgear vs Untreated control (no treatment)
ANB · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion) · End of treatment
Orthodontic treatment for prominent lower front teeth (Class III malocclusion) in children (2024) · Cochrane
Arun 1994 (n=60): ANB data not usable (no SDs); Mann-Whitney P<0.001 benefit for mandibular headgear. Effect ~0.5 degrees, probably not clinically significant.1 study · 60 participantsUngraded
Reverse Twin Block with lip pads and rapid maxillary expander (RME) vs Untreated control (no treatment)
ANB · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion) · End of treatment
Orthodontic treatment for prominent lower front teeth (Class III malocclusion) in children (2024) · Cochrane
MD 3.66 [2.73, 4.59]1 study · 26 participantsUngraded
Opal Seal fluoride-releasing primer vs Conventional Transbond XT primer
White spot lesion area · Patients undergoing fixed orthodontic treatment · During orthodontic treatment
Can Orthodontic Adhesive Systems Inhibit the Formation and Development of White Spot Lesions During Fixed… (2024)
There was no significant difference in the WSL area between the two groups, with the mean WSL area measuring 161.3 mm2 in the Opal Seal group and 1361.2 mm2 in the conventional group.1 study · 56 participantsUngraded
Reverse Forsus vs Untreated control (no treatment)
ANB · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion) · End of treatment
Orthodontic treatment for prominent lower front teeth (Class III malocclusion) in children (2024) · Cochrane
MD 2.84 [1.89, 3.79]1 study · 22 participantsUngraded
Non-surgical orthodontic treatment (any: facemask, chin cup, tandem traction bow, mandibular headgear, ORTA, reverse Twin Block, Reverse Forsus) vs No treatment
Overjet · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion) · End of treatment (9 to 15 months)
Orthodontic treatment for prominent lower front teeth (Class III malocclusion) in children (2024) · Cochrane
MD 5.03 [3.81, 6.25]4 studies · 184 participantsModerate
Orthodontic adhesives containing nano-amorphous calcium phosphate (n-ACP) particles/nanoparticles vs Conventional/control orthodontic adhesive (e.g., Transbond XT) or negative control
Enamel remineralization extent · Human enamel specimens around orthodontic brackets (in vitro) · pH cycling / biofilm challenge 14 to 28 days, Overall
Remineralization and anti-demineralization effect of orthodontic adhesives on enamel surrounding orthodontic… (2024)
Studies using orthodontic adhesives containing n-ACP showed statistically significant remineralization compared with control orthodontic adhesives [15, 33].2 studiesUngraded
Facemask vs Untreated control (no treatment)
Wits appraisal · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion) · End of treatment
Orthodontic treatment for prominent lower front teeth (Class III malocclusion) in children (2024) · Cochrane
MD 3.58 [2.78, 4.37]2 studies · 72 participantsUngraded
Orthodontic adhesives containing bioactive glass (BAG) particles/nanoparticles (including Ag-, Zn-, fluoride-, or Ga-doped BAG) vs Conventional/control orthodontic adhesive (e.g., Transbond XT) or negative control
Enamel remineralization / anti-demineralization extent · Human enamel specimens around orthodontic brackets (in vitro) · pH cycling 14 days to 6 months (majority 14 days), Overall
Remineralization and anti-demineralization effect of orthodontic adhesives on enamel surrounding orthodontic… (2024)
Out of 13 studies that evaluated bioactive glass particles/nanoparticles, 9 reported definitive statistically significant remineralization potential compared to control orthodontic adhesives [17, 21-24, 26-28, 31]; one…13 studiesUngraded
Surgically-anchored orthodontic treatment (miniplates) vs Untreated control (no treatment)
Overjet · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion) · End of treatment
Orthodontic treatment for prominent lower front teeth (Class III malocclusion) in children (2024) · Cochrane
MD 7.69 [6.99, 8.40]1 study · 30 participantsLow
Facemask vs Untreated control (no treatment)
Overjet · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion) · End of treatment (9 to 15 months)
Orthodontic treatment for prominent lower front teeth (Class III malocclusion) in children (2024) · Cochrane
MD 5.04 [4.29, 5.80]2 studies · 92 participantsUngraded
Facemask with rapid maxillary expansion (RME) vs Facemask only
Wits appraisal · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion) · End of treatment
Orthodontic treatment for prominent lower front teeth (Class III malocclusion) in children (2024) · Cochrane
MD 0.10 [-1.08, 1.29]2 studies · 60 participantsUngraded
Single-strand superelastic NiTi arch wire vs Coaxial superelastic NiTi arch wire
Alignment rate · People receiving orthodontic treatment with fixed appliances (upper and/or lower full arch) · 4 weeks
Initial arch wires used in orthodontic treatment with fixed appliances (2024) · Cochrane
MD -2.64 [-4.61, -0.67]2 studies · 64 participantsModerate
Facemask with rapid maxillary expansion (RME) vs Reverse chin cup
ANB · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion) · End of treatment
Orthodontic treatment for prominent lower front teeth (Class III malocclusion) in children (2024) · Cochrane
MD 0.20 [-0.71, 1.11]1 study · 42 participantsUngraded
Amorphous calcium phosphate (ACP)-containing light-cure adhesive vs Conventional adhesive (Transbond XT)
Enamel demineralization (DIAGNOdent) · Patients undergoing fixed orthodontic (fixed appliance) treatment (adolescents and adults, ages 12 to 35) · 1 and 6 months
Can Orthodontic Adhesive Systems Inhibit the Formation and Development of White Spot Lesions During Fixed… (2024)
Alshammari 2019 (1 triple-blinded RCT, 26 patients / 255 teeth): DIAGNOdent demineralization scores were lower with ACP than control at 1 month (2.58 +/-1.11 vs 3.39 +/-1.29) and 6 months (3.41 +/-1.11 vs 4.32…1 study · 26 participantsUngraded
Tandem traction bow appliance vs Untreated control (no treatment)
ANB · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion) · End of treatment
Orthodontic treatment for prominent lower front teeth (Class III malocclusion) in children (2024) · Cochrane
MD 1.70 [1.09, 2.31]1 study · 30 participantsUngraded
Facemask vs Untreated control (no treatment)
Self-esteem (Piers-Harris self-concept scale) · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion) · 3-year follow-up
Orthodontic treatment for prominent lower front teeth (Class III malocclusion) in children (2024) · Cochrane
MD 0.60 [-2.57, 3.77]1 study · 63 participantsUngraded
Facemask with rapid maxillary expansion (RME) vs Facemask with alternating rapid maxillary expansion and constriction (Alt-RAMEC)
ANB · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion) · End of treatment
Orthodontic treatment for prominent lower front teeth (Class III malocclusion) in children (2024) · Cochrane
MD -0.46 [-1.03, 0.10]4 studies · 131 participantsLow
Antibacterial S. mutans reduction only in Farzanegan (chitosan+TiO2); Mollabashi (TiO2-only) showed no significant antibacterial effect - not attributable to TiO2 alone vs Conventional adhesive/composite (Transbond XT)
Antibacterial effect (Streptococcus mutans count, real-time PCR) · Patients undergoing fixed orthodontic (fixed appliance) treatment (adolescents and adults, ages 12 to 35) · 1 day to 6 months, Antibacterial (S. mutans)
Can Orthodontic Adhesive Systems Inhibit the Formation and Development of White Spot Lesions During Fixed… (2024)
Two RCTs gave conflicting antibacterial results: Farzanegan 2021 reported a significant decrease in S. mutans with the chitosan plus TiO2 adhesive (p=0.01 lateral incisors; p=0.001 second premolars); Mollabashi 2022…2 studies · 64 participantsUngraded
Light-cured resin-modified glass ionomer cement vs Resin adhesive (Transbond XT)
First-time bracket failure · Patients undergoing fixed orthodontic treatment · Before and after treatment
Can Orthodontic Adhesive Systems Inhibit the Formation and Development of White Spot Lesions During Fixed… (2024)
No differences were observed in the proportions of patients experiencing first-time bracket failures when participants were bonded with either resin adhesive or RM-GIC (p > 0.05).1 study · 197 participantsUngraded
Chin cup (600 g force) vs Chin cup (300 g force)
Wits appraisal · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion) · End of treatment
Orthodontic treatment for prominent lower front teeth (Class III malocclusion) in children (2024) · Cochrane
MD -0.30 [-1.12, 0.52]1 study · 40 participantsUngraded
Fixed orthodontic treatment with fixed (multibracket) appliances (exposure) vs None (single-group prevalence/incidence estimate)
Incidence of new ICLs (proportion of tooth surfaces developing new lesions) · Patients undergoing fixed orthodontic treatment with fixed (multibracket) appliances, followed for development of new… · During fixed orthodontic treatment (development of new lesions), Overall (random-effects model)
Distribution of initial caries lesions in relation to fixed orthodontic therapy. A systematic review and… (2024)
Proportion 0.15 [0.08, 0.26]4 studies · 1890 participantsVery low
Hybrid Hyrax (RME) with miniscrews and Class III elastics vs Conventional Hyrax (RME) with miniscrews and Class III elastics
Overjet · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion) · End of treatment
Orthodontic treatment for prominent lower front teeth (Class III malocclusion) in children (2024) · Cochrane
MD 0.91 [-0.56, 2.38]1 study · 35 participantsUngraded
Adhesive precoated flash-free brackets vs Conventional ceramic brackets
Enamel demineralization (DIAGNOdent score) · Patients undergoing fixed orthodontic treatment · Baseline, 1 month, and 6 months after bonding
Can Orthodontic Adhesive Systems Inhibit the Formation and Development of White Spot Lesions During Fixed… (2024)
Intergroup evaluation showed that there were no statistically significant differences in demineralization measurements between all sides of the conventional and flash-free brackets at all the time intervals (p >0.05).1 study · 30 participantsUngraded
Superelastic NiTi arch wire vs Conventional (stabilised) NiTi arch wire
Root resorption · People receiving orthodontic treatment with fixed appliances (upper and/or lower full arch)
Initial arch wires used in orthodontic treatment with fixed appliances (2024) · Cochrane
Root resorption: not reported0 studiesNo studies
Transbond XT with 1% chitosan and 1% TiO2 nanoparticles vs Transbond XT adhesive
Streptococcus mutans count · Patients undergoing fixed orthodontic treatment · 1 day, 2 months, and 6 months after bonding
Can Orthodontic Adhesive Systems Inhibit the Formation and Development of White Spot Lesions During Fixed… (2024)
Experimental group: significant decrease in S. mutans count was observed at the time points of 1 day, 2 months, and 6 months for both maxillary lateral incisor (p = 0.01) and maxillary second premolar teeth (p = 0.001).1 study · 24 participantsUngraded