Radiographic proximal caries lesion progression · Patients with non-cavitated proximal (approximal) caries lesions (primary or permanent dentition)
Resin infiltration probably reduces the odds of proximal lesion progression compared with non-invasive treatment (OR 0.21, 95% CI 0.15 to 0.29; moderate certainty).
6 findings from 1 review
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OR 0.32 [0.01, 8.27]
1 study
GRADE not reported
OR 0.14 [0.05, 0.37]
2 studies
GRADE not reported
OR 0.38 [0.18, 0.81]
1 study
GRADE not reported
Intervention not reported
Dental caries prevalence · General population (children and adults) in East Africa
Caries prevalence was highest in Eritrea at 65.2% (95% CI 49.2 to 81.1); certainty not graded.
1 finding from 1 review
Intervention not reported
Dental caries prevalence · General population in Ethiopia (all ages, age range 6-100 years)
Caries prevalence in the Amhara region was 40.44% (95% CI 24.67 to 56.21); certainty not graded.
1 finding from 1 review
Patient/dentist satisfaction · Patients with dental fluorosis
Patient/dentist satisfaction did not differ between bleaching-then-infiltration and infiltration alone (SMD -1.53, 95% CI -4.75 to 1.70; ungraded).
1 finding from 1 review
SMD -1.53 [-4.75, 1.70]
2 studies
GRADE not reported
Atherosclerotic cardiovascular disease (ACVD)-related events (morbidity and mortality) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies
In prospective cohorts, the multivariable-adjusted HR for ACVD-related events in edentulous adults (0 teeth) vs adults with 1-32 teeth was 1.21 (95% CI 1.07 to 1.36; 5 studies, I2=35%); GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).
4 findings from 1 review
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Dental caries prevalence · Children with cerebral palsy in Dubai
Dental caries prevalence was 53% among children with cerebral palsy.
1 finding from 1 review
Prevalence 53
1 study
GRADE not reported
Gingivitis · School children aged 3-12 years in Sharjah clinic
Male children had lower odds of gingivitis than female children.
1 finding from 1 review
Dental caries in children · Children in cross-sectional studies
The cross-sectional association remained statistically significant after excluding Julihn et al. 2018.
7 findings from 1 review
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Dental caries susceptibility · Children and adults (no age limit) assessed for dental caries susceptibility
No significant association between the TaqI (rs731236 T>C) polymorphism and dental caries in Caucasians under the heterozygous (CT vs TT) model (OR 0.93, 95% CI 0.56 to 1.56); ungraded.
6 findings from 1 review
Association Between the TaqI (rs731236 T>C) Gene Polymorphism and Dental Caries Risk: A Meta-analysis. 2021 All outcomesCase-control studies of children and adults (China, India, Czech Republic, Turkey) · Ethnicity: Caucasian
OR 0.93 [0.56, 1.56]
2 studies · 538 participants
GRADE not reported
Association Between the TaqI (rs731236 T>C) Gene Polymorphism and Dental Caries Risk: A Meta-analysis. 2021 All outcomesCase-control studies of children and adults (China, India, Czech Republic, Turkey) · Dentition: Deciduous tooth decay
OR 1.40 [0.91, 2.15]
2 studies · 929 participants
GRADE not reported
Association Between the TaqI (rs731236 T>C) Gene Polymorphism and Dental Caries Risk: A Meta-analysis. 2021 All outcomesCase-control studies of children and adults (China, India, Czech Republic, Turkey) · Dentition: Permanent tooth caries
OR 1.65 [0.33, 8.35]
3 studies · 1271 participants
GRADE not reported
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Association Between the TaqI (rs731236 T>C) Gene Polymorphism and Dental Caries Risk: A Meta-analysis. 2021 All outcomesCase-control studies of children and adults (China, India, Czech Republic, Turkey) · Ethnicity: Asian
OR 1.67 [0.96, 2.90]
5 studies · 1932 participants
GRADE not reported
Association Between the TaqI (rs731236 T>C) Gene Polymorphism and Dental Caries Risk: A Meta-analysis. 2021 All outcomesCase-control studies of children and adults (China, India, Czech Republic, Turkey) · Overall
OR 1.41 [0.89, 2.22]
7 studies · 2470 participants
GRADE not reported
Association Between the TaqI (rs731236 T>C) Gene Polymorphism and Dental Caries Risk: A Meta-analysis. 2021 All outcomesCase-control studies of children and adults (China, India, Czech Republic, Turkey) · Dentition: Mixed dentition caries
OR 1.34 [0.75, 2.40]
2 studies · 270 participants
GRADE not reported
Gingival index (GI) · Adults undergoing orthodontic treatment
A single study found no significant difference in gingival index between aligners and fixed appliances in adults at 6-12 weeks (MD -0.10, 95% CI -0.35 to 0.15; ungraded).
1 finding from 1 review
MD -0.10 [-0.35, 0.15]
1 study
GRADE not reported
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) · Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces
In in vitro, laser fluorescence pen (2190) pooled specificity was 0.77 (95% CI 0.62 to 0.88) for occlusal caries at the dentin detection level; ungraded.
4 findings from 1 review
Specificity 0.77 [0.62, 0.88]
4 studies
GRADE not reported
Sensitivity 0.63 [0.37, 0.83]
4 studies
GRADE not reported
DOR 5.85 [1.77, 19.30]
4 studies
GRADE not reported
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AUC 0.78
4 studies
GRADE not reported
Mean number of decayed teeth (mean DT) · Adults (general and hospital populations assessed in case-control studies)
Systemic sclerosis patients have a significantly higher number of decayed teeth than controls (SMD 0.19); certainty ungraded.
1 finding from 1 review
SMD 0.186 [0.007, 0.365]
3 studies
GRADE not reported
Diagnostic accuracy for proximal caries detection (caries detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro)
Under in vitro conditions, laser fluorescence (DIAGNOdent 2190) had a summary ROC AUC of 0.91 for proximal caries detection at the caries detection level; ungraded.
4 findings from 1 review
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Dental caries · School children aged 11-17 years in Sharjah
Arab ethnicity was associated with higher DMFT.
1 finding from 1 review
Diagnostic accuracy for proximal caries detection (1/3 dentin detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro)
Under in vitro conditions, visual examination had a pooled specificity of 0.84 (95% CI 0.76, 0.89) for proximal caries detection at the 1/3 dentin detection level; ungraded.
4 findings from 1 review
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Molar-incisor hypomineralization prevalence · School children aged 8-12 years in Dubai public schools
MIH prevalence was 32.6% in females versus 18.1% in males.
1 finding from 1 review
Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) · Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces
In in vitro, digital bitewing radiography (phosphor plates) pooled specificity was 0.95 (95% CI 0.59 to 0.995) for occlusal caries at the dentin detection level; ungraded.
4 findings from 1 review
Specificity 0.95 [0.59, 0.995]
2 studies
GRADE not reported
AUC 0.73
2 studies
GRADE not reported
Sensitivity 0.48 [0.24, 0.73]
2 studies
GRADE not reported
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DOR 15.57 [0.47, 515.27]
2 studies
GRADE not reported
Initiation of white spot lesions (WSL), visual-tactile assessment · Patients of any age (11-40 years) receiving comprehensive/fixed orthodontic treatment with fixed appliances
There is no clear difference in WSL initiation between glass ionomer cement and resin adhesive for bracket bonding (RR 0.72, not significant); certainty of evidence is very low.
1 finding from 1 review
Radiographic proximal caries lesion progression · Patients with non-cavitated proximal (approximal) caries lesions (primary or permanent dentition)
Sealing probably reduces the odds of proximal lesion progression compared with placebo (OR 0.27, 95% CI 0.18 to 0.42; moderate certainty).
1 finding from 1 review
Intervention not reported
Dental caries prevalence · General population in Ethiopia (all ages, age range 6-100 years)
Caries prevalence in other regions (Oromia, Harar, SNNPR) was 42.90% (95% CI 24.68 to 61.12); certainty not graded.
1 finding from 1 review