Opioids vs Placebo, no intervention or usual care (with or without placebo)
Days treatment · newborn infants with opioid withdrawal
1 finding from 1 review
- no estimate extracted1 study · 80 participantsVery low
Findings
What do systematic reviews say?
315 questions · 322 findings · 87 reviews · Neonatal
No studies found 47 · 14.6%GRADE not reported 18 · 5.6%Very low 78 · 24.2%Low 105 · 32.6%Moderate 50 · 15.5%High 24 · 7.5%
Intervention not reported
Time taken to establish full gavage feeding (days) · intermittent bolus gavage tube feeding of preterm and low birth weight infants
1 finding from 1 review
- Push versus gravity for intermittent bolus gavage tube feeding of preterm and low birth weight infants 2021 · Cochrane Headline outcomes onlyno estimate extracted0 participantsGRADE not reported
Intervention not reported
Feeding intolerance (number of episodes per day) · intermittent bolus gavage tube feeding of preterm and low birth weight infants
1 finding from 1 review
- Push versus gravity for intermittent bolus gavage tube feeding of preterm and low birth weight infants 2021 · Cochrane Headline outcomes onlyno estimate extracted0 participantsGRADE not reported
Breast feeding with supplemental feeds by other than bottle vs breast feeding with supplemental feeds by bottle (all trials)
Length of hospital stay · preterm infants
1 finding from 1 review
- Avoidance of bottles during the establishment of breastfeeds in preterm infants 2021 · Cochrane Headline outcomes onlyno estimate extracted4 studies · 1004 participantsLow
Intervention not reported
Duration of supplemental oxygen (days) · preterm infants less than 30 weeks' gestational age requiring conventional mechanical ventilation for respiratory distress syndrome
1 finding from 1 review
- Lung recruitment manoeuvres for reducing mortality and respiratory morbidity in mechanically ventilated neonates 2021 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 44 participantsVery low
Intervention not reported
Duration of ventilatory support (days) · preterm infants less than 30 weeks' gestational age requiring conventional mechanical ventilation for respiratory distress syndrome
1 finding from 1 review
- Lung recruitment manoeuvres for reducing mortality and respiratory morbidity in mechanically ventilated neonates 2021 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 44 participantsVery low
Intervention not reported
Duration of continuous positive airway pressure therapy (hours or days) · preterm infants less than 30 weeks' gestational age requiring conventional mechanical ventilation for respiratory distress syndrome
The review found no eligible studies for this question.
1 finding from 1 review
- Lung recruitment manoeuvres for reducing mortality and respiratory morbidity in mechanically ventilated neonates 2021 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Intervention not reported
Duration of neonatal intensive care unit stay (hours or days) · preterm infants less than 30 weeks' gestational age requiring conventional mechanical ventilation for respiratory distress syndrome
The review found no eligible studies for this question.
1 finding from 1 review
- Lung recruitment manoeuvres for reducing mortality and respiratory morbidity in mechanically ventilated neonates 2021 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Intervention not reported
Duration of hospital stay (days) · preterm infants less than 30 weeks' gestational age requiring conventional mechanical ventilation for respiratory distress syndrome
The review found no eligible studies for this question.
1 finding from 1 review
- Lung recruitment manoeuvres for reducing mortality and respiratory morbidity in mechanically ventilated neonates 2021 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Restricted vs standard fluid management
Length of hospital stay · late preterm and full‐term infants with transient tachypnea of the newborn
1 finding from 1 review
- Fluid restriction in the management of transient tachypnea of the newborn 2021 · Cochrane Headline outcomes onlyno estimate extracted1 study · 80 participantsVery low
Salbutamol vs placebo/no treatment
Length of hospital stay · patients with the management of transient tachypnea of the newborn
1 finding from 1 review
- no estimate extracted4 studies · 338 participantsLow
Short feeding interval vs long feeding interval
Days taken to achieve full feeding · preterm infants less than 1500 grams
1 finding from 1 review
- Short versus long feeding interval for bolus feedings in very preterm infants 2021 · Cochrane Headline outcomes onlyno estimate extracted3 studies · 351 participantsLow
Short feeding interval vs long feeding interval
Days to regain birth weight · preterm infants less than 1500 grams
1 finding from 1 review
- Short versus long feeding interval for bolus feedings in very preterm infants 2021 · Cochrane Headline outcomes onlyno estimate extracted3 studies · 350 participantsLow
Short feeding interval vs long feeding interval
Length of hospital stay · preterm infants less than 1500 grams
1 finding from 1 review
- Short versus long feeding interval for bolus feedings in very preterm infants 2021 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 207 participantsVery low
Short feeding interval vs long feeding interval
Rate of weight gain (g/kg/day) · preterm infants less than 1500 grams
The review found no eligible studies for this question.
1 finding from 1 review
- Short versus long feeding interval for bolus feedings in very preterm infants 2021 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
High vs standard volume of fortified human milk or preterm formula
Weight gain · preterm or low birth weight infants
1 finding from 1 review
- High versus standard volume enteral feeds to promote growth in preterm or low birth weight infants 2021 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 271 participantsModerate
High vs standard volume of unfortified human milk or term formula
Weight gain · preterm or low birth weight infants
1 finding from 1 review
- High versus standard volume enteral feeds to promote growth in preterm or low birth weight infants 2021 · Cochrane Headline outcomes onlyno estimate extracted1 study · 61 participantsModerate
Summary of Findings Table ‐ Low vs moderate‐high nasal continuous positive airway pressure levels
BPD at 28 days · health problem or population
The review found no eligible studies for this question.
2 findings from 1 review
- Nasal continuous positive airway pressure levels for the prevention of morbidity and mortality in preterm infants 2021 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
- Nasal continuous positive airway pressure levels for the prevention of morbidity and mortality in preterm infants 2021 · Cochrane Headline outcomes onlyRR 1.1 [0.56, 2.17]1 study · 271 participantsVery low
Indomethacin vs placebo or control
Bronchopulmonary dysplasia at 28 days · symptomatic patent ductus arteriosus in preterm infants
Indomethacin showed no clear difference in bronchopulmonary dysplasia at 28 days compared with placebo or control (low certainty).
1 finding from 1 review
- Indomethacin for symptomatic patent ductus arteriosus in preterm infants 2021 · Cochrane Headline outcomes onlyRR 1.45 [0.6, 3.51]1 study · 55 participantsLow
Sunlight (with or without filters or amplification) vs other sources of phototherapy
Proportion of days of effective treatmenti · infants with confirmed hyperbilirubinemia
It is very uncertain whether sunlight (with or without filters or amplification) changes proportion of days of effective treatmenti compared with other sources of phototherapy (very low certainty).
1 finding from 1 review
- Sunlight for the prevention and treatment of hyperbilirubinemia in term and late preterm neonates 2021 · Cochrane Headline outcomes onlyRR 1.02 [0.97, 1.06]2 studies · 621 participantsVery low