Cochrane · systematic review · CD012322

Short versus long feeding interval for bolus feedings in very preterm infants

Ibrahim, NR, Van Rostenberghe, H, Ho, JJ, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library

NeonatalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
4
No studies
1
Included studies
NR
No studies 1 · 20%Ungraded 0 · 0%Very low 1 · 20%Low 3 · 60%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Short feeding interval compared to long feeding interval for bolus feeding in very preterm infants

Population: preterm infants < 1500 g
5 questions
OutcomeEffectEvidenceStatus / GRADE
Days taken to achieve full feeding
Short feeding interval vs long feeding interval
no estimate extracted3 studies · 351 participantsLow
Downgraded: risk of bias, imprecision
Days to regain birth weight
Short feeding interval vs long feeding interval
no estimate extracted3 studies · 350 participantsLow
Downgraded: risk of bias, imprecision
Duration of hospital stay (days)
Short feeding interval vs long feeding interval
no estimate extracted2 studies · 207 participantsVery low
Downgraded: risk of bias, imprecision
Necrotising enterocolitis
Short feeding interval vs long feeding interval
RR 1.07 [0.54, 2.11]4 studies · 417 participantsLow
Downgraded: risk of bias, imprecision
Growth during hospital stay (weight gain in g/kg/day)
Short feeding interval vs long feeding interval
no estimate extractedNRNo studies