Cochrane · systematic review · CD009969

Lung recruitment manoeuvres for reducing mortality and respiratory morbidity in mechanically ventilated neonates

Blazek, EV, East, CE, Jauncey-Cooke, J, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library

NeonatalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
4
No studies
3
Included studies
NR
No studies 3 · 42.9%Ungraded 0 · 0%Very low 2 · 28.6%Low 2 · 28.6%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Summary of findings for the main comparison

Population: preterm infants less than 30 weeks' gestational age requiring conventional mechanical ventilation for respiratory distress syndrome
7 questions
OutcomeEffectEvidenceStatus / GRADE
Mortality by hospital discharge
RR 1 [0.17, 5.77]2 studies · 44 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Incidence of bronchopulmonary dysplasia
RR 0.25 [0.03, 2.07]2 studies · 44 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Duration of supplemental oxygen (days)
no estimate extracted2 studies · 44 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Duration of ventilatory support (days)
no estimate extracted2 studies · 44 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Duration of continuous positive airway pressure therapy (hours or days)
no estimate extractedNRNo studies
Duration of neonatal intensive care unit stay (hours or days)
no estimate extractedNRNo studies
Duration of hospital stay (days)
no estimate extractedNRNo studies