Cochrane · systematic review · CD012413

High versus standard volume enteral feeds to promote growth in preterm or low birth weight infants

Abiramalatha, T, Thomas, N, Thanigainathan, S · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library

Neonatal2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
10
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 3 · 30%Very low 2 · 20%Low 3 · 30%Moderate 2 · 20%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Show all 2 versions

High compared to standard volume of fortified human milk or preterm formula in preterm or low birth weight infants

Population: preterm or low birth weight infants
5 questions
OutcomeEffectEvidenceStatus / GRADE
Weight gain during hospital stay (g/kg/day)
High vs standard volume of fortified human milk or preterm formula
no estimate extracted2 studies · 271 participantsModerate
Downgraded: imprecision
Linear growth during hospital stay (cm/week)
High vs standard volume of fortified human milk or preterm formula
no estimate extracted2 studies · 271 participantsLow
Downgraded: imprecision
Head growth during hospital stay (cm/week)
High vs standard volume of fortified human milk or preterm formula
no estimate extracted2 studies · 271 participantsLow
Downgraded: imprecision
Extrauterine growth restriction at discharge
High vs standard volume of fortified human milk or preterm formula
RR 0.71 [0.5, 1.02]2 studies · 271 participantsLow
Downgraded: imprecision
Necrotising enterocolitis
High vs standard volume of fortified human milk or preterm formula
RR 0.74 [0.12, 4.51]2 studies · 283 participantsVery low
Downgraded: risk of bias, imprecision

High compared to standard volume of unfortified human milk or term formula in preterm or low birth weight infants

Population: preterm or low birth weight infants
5 questions
OutcomeEffectEvidenceStatus / GRADE
Weight gain during hospital stay (g/kg/day)
High vs standard volume of unfortified human milk or term formula
no estimate extracted1 study · 61 participantsModerate
Downgraded: imprecision
Linear growth (cm/week)
High vs standard volume of unfortified human milk or term formula
no estimate extracted0 studies · 0 participantsUngraded
Head growth (cm/week)
High vs standard volume of unfortified human milk or term formula
no estimate extracted0 studies · 0 participantsUngraded
Extrauterine growth restriction at discharge
High vs standard volume of unfortified human milk or term formula
no estimate extracted0 studies · 0 participantsUngraded
Necrotising enterocolitis
High vs standard volume of unfortified human milk or term formula
RR 1.03 [0.07, 15.78]1 study · 61 participantsVery low
Downgraded: risk of bias, imprecision