Search review questions

Dental caries prevalence · Pakistani population of any sex or age · 2009 to 2020, Pakistan, Fixed-effects model

Prevalence of periodontitis · Adults (general and hospital populations assessed in case-control studies) · Hospital/clinic-based case-control studies from Asia, America and Europe

Diagnostic accuracy for proximal caries detection (1/3 dentin detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro) · In vitro (laboratory; extracted teeth); permanent posterior teeth, proximal surfaces, 1/3 dentin detection level

All-cause mortality (ACM) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies · Community-based and clinical cohorts worldwide (all continents); events ascertained from medical records, death certificates/registers, or self-report

Secondary caries · People with permanent or adult posterior teeth requiring restoration (parallel-group trials involved children aged 6… · Follow-up >= 3 years, Parallel-group and split-mouth trials combined

Incidence of new white spot lesions by visual-tactile assessment · Patients receiving comprehensive fixed orthodontic treatment · 12 to 24 months, Fixed orthodontic treatment, Overall

Care index · Emirati preschool children in Ras Al Khaimah nurseries · Overall

Daily tooth brushing · School-aged children in Sharjah · Females

S. mutans presence (CFU > 10^5) · Adults undergoing orthodontic treatment · 3 months, Adults

Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Case-control studies of children and adults (China, India, Czech Republic, Turkey), Dentition: Permanent tooth caries

Diagnostic accuracy for proximal caries detection (caries detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro) · In vitro (laboratory; extracted teeth); permanent posterior teeth, proximal surfaces, Caries detection level

Outcome NR · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer

Specificity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted… · Up to 3 months between index test and reference standard (in vivo studies), Dentine-caries (D3) prevalence high >=35% or unreported (non-CBCT)

Incidence of successfully erupted PDC that were favourably positioned · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC) · 24 months

Dental caries prevalence · General population in Ethiopia (all ages, age range 6-100 years) · Community-, school-, and hospital/clinic-based populations across regions of Ethiopia, Addis Ababa

Sensitivity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted… · Up to 3 months between index test and reference standard (in vivo studies), Analogue and digital combined (non-CBCT); 97 datasets

Lower incisors to mandible at 6 months · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth · 6 months

Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Case-control studies of children and adults (China, India, Czech Republic, Turkey), Overall

Dental caries prevalence · General Pakistani population (all ages and both sexes; predominantly children and adolescents) · Pakistan (school-, community-, and hospital/clinic-based cross-sectional surveys), City: Islamabad and Rawalpindi (combined)

Failure of therapy · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious… · 24 months, Cavitated but not deep lesions, primary dentition

Sensitivity (test accuracy for detecting enamel caries) · Children, adolescents, or adults presenting asymptomatically or suspected of early enamel caries (in vivo), or… · Up to 3 months between index test and reference standard (in vivo studies)

Mean dmft · Preschool children attending Al Ain pediatric dentistry department · Overall

Canine expansion · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or… · 7 to 15 weeks after start of treatment

Radiographic proximal caries lesion progression · Patients with non-cavitated proximal caries lesions · Longest available follow-up

Dental caries prevalence · General population (children and adults) in East Africa · Community- and school-based populations, East Africa, Eritrea

Diagnostic accuracy for proximal caries detection (caries detection level) · Patients with permanent posterior teeth, proximal surfaces assessed clinically (in vivo) · In vivo (clinical); permanent posterior teeth, proximal surfaces, Caries detection level

Amount of crowding (change in mandibular crowding) at 8 weeks · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth · 8 weeks

Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Case-control studies of children and adults (China, India, Czech Republic, Turkey), Overall

Diagnostic accuracy for proximal caries detection (1/3 dentin detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro) · In vitro (laboratory; extracted teeth); permanent posterior teeth, proximal surfaces, 1/3 dentin detection level

Specificity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted… · Up to 3 months between index test and reference standard (in vivo studies), Setting: in vitro (non-CBCT)

Size of the jaws (maxillary and mandibular arch length) · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth · 2 to 8 years

Size of the lower jaw (mandibular arch length) at 6 months · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth · 6 months

Specificity (COE plus vital rinsing arm) · OSCC or OPMD symptom-free individuals with tobacco habits

Dental caries prevalence · General population in Ethiopia (all ages, age range 6-100 years) · Community-, school-, and hospital/clinic-based populations across regions of Ethiopia, Amhara

Failure of therapy · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious… · 6-36 months, Deep lesions, primary dentition

Patient/dentist satisfaction · Patients with dental fluorosis

Any other adverse effects, such as gingival disease and demineralisation · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC)

Diagnostic accuracy for proximal caries detection (dentin detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro) · In vitro (laboratory; extracted teeth); permanent posterior teeth, proximal surfaces, Dentin detection level

Diagnostic accuracy: analogue versus CBCT (within-person, not pooled) · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted… · Up to 3 months between index test and reference standard (in vivo studies)

Heart rate · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

Aesthetic outcomes of future prosthodontic rehabilitation · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring… · 6 to 36 months

Diagnostic accuracy: in vitro versus in vivo comparison · Asymptomatic children or adults presenting for clinical examination (in vivo studies), or extracted teeth of children… · Up to 3 months between index test and reference standard (in vivo studies), Study setting (in vitro vs in vivo)

Costs: direct cost of treatment · Dental patients undergoing direct or indirect restorative treatment (no age or gender restriction)

Change in diastolic blood pressure (DBP, mmHg) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension · Short term (follow-up 2-3 months), People diagnosed with periodontitis

Pocket probing depth (PPD) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension · Long term, People diagnosed with periodontitis and other cardiovascular diseases except hypertension

Safety issues (adverse events) · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious…

Atherosclerotic cardiovascular disease (ACVD)-related events (morbidity and mortality) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies · Community-based and clinical cohorts worldwide (all continents); events ascertained from medical records, death certificates/registers, or self-report, Multivariable-adjusted

Dental caries prevalence · Children with cerebral palsy in Dubai · Overall

Outcome NR · Apparently healthy adults not reporting symptoms of OPMD or OSCC, attending an organised screening or surveillance…

Gingivitis · School children aged 3-12 years in Sharjah clinic · Overall