Search review questions

Mean DMFT · School children aged 11-17 years in Sharjah · Overall

Bleeding on probing (BOP) · Adults (general and hospital populations assessed in case-control studies)

Mean DMFT (decayed, missing, filled permanent teeth) · Individuals with permanent dentition in East Africa · Uganda

Sensitivity for detection of enamel/early caries · Children or adults presenting asymptomatically or suspected of having enamel caries (clinical/in vivo studies);… · Up to 3 months between index test and reference standard (in vivo; in vitro no limit if stored appropriately)

Water samples with fluoride concentration above the acceptable range · Artificially fluoridated public water supply in Brazilian cities (water samples under external control) · Region: Northeast Brazil

Streptococcus mutans load in the oral cavity (saliva and/or dental plaque) · Adults and children (general population) · Final/end-of-study time point (follow-up 2 weeks to 18 months), Overall (vs all controls)

Oral health knowledge, attitudes and practices (mothers/caregivers) · Mothers and caregivers of children in the United Arab Emirates

Dental caries prevalence · General Pakistani population (all ages and both sexes; predominantly children and adolescents) · City: Lahore

Dental plaque levels · Children in the United Arab Emirates (Ajman, Sharjah)

Molar-incisor hypomineralization prevalence · School children in Dubai governmental schools · Overall

Atherosclerotic cardiovascular disease (ACVD)-related events (morbidity and mortality) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies

Childhood dental caries · Children in cross-sectional studies · Sensitivity: excluded Tanaka et al. 2009

Diagnostic accuracy for proximal caries detection (caries detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro) · Caries detection level

Specificity for detection of enamel caries · Asymptomatic children or adults presenting for clinical examination (in vivo studies), or extracted teeth of children… · Up to 3 months between index test and reference standard (in vivo studies), Low prevalence of dentine caries (0% to 14%)

Atherosclerotic cardiovascular disease (ACVD)-related events (morbidity and mortality) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies · Multivariable-adjusted

Specificity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted… · Up to 3 months between index test and reference standard (in vivo studies), Setting: in vivo / clinical (non-CBCT)

Attachment loss (AL) · Adults (general and hospital populations assessed in case-control studies)

Radiographic proximal caries lesion progression · Patients with non-cavitated proximal (approximal) caries lesions (primary or permanent dentition) · Longest available follow-up, All caries-risk levels (caries-risk subset)

Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) · Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces

Sensitivity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted… · Up to 3 months between index test and reference standard (in vivo studies), Occlusal surfaces (non-CBCT)

Number of filled teeth · Adults (general and hospital populations assessed in case-control studies)

Sensitivity for detection of oral cavity cancer/OPMD · Apparently healthy adults not reporting symptoms of OPMD or OSCC, attending an organised screening or surveillance…

Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Overall

Mean DMFT (decayed, missing, filled permanent teeth) · Individuals with permanent dentition in East Africa · Sudan

Sensitivity for detection of enamel caries · Asymptomatic children or adults presenting for clinical examination (in vivo studies), or extracted teeth of children… · Up to 3 months between index test and reference standard (in vivo studies), Histology reference standard

Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) · Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces

Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) · Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces

Sensitivity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted… · Up to 3 months between index test and reference standard (in vivo studies), Primary dentition (non-CBCT)

Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) · Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces

Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Dentition: Mixed dentition caries

Sensitivity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted… · Up to 3 months between index test and reference standard (in vivo studies), Proximal surfaces (non-CBCT)

Specificity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted… · Up to 3 months between index test and reference standard (in vivo studies), Reference standard: enhanced visual (non-CBCT)

Water samples with fluoride concentration outside the acceptable range · Artificially fluoridated public water supply in Brazilian cities (water samples under external control) · Region: Northeast Brazil

Atherosclerotic cardiovascular disease (ACVD)-related events (morbidity and mortality) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies

Radiographic proximal caries lesion progression · Patients with non-cavitated proximal caries lesions · Longest available follow-up, Caries risk: high

Optical/esthetic improvement (visual-tactile assessment) · Patients with post-orthodontic white spot lesions (WSL) · 4 weeks to 6 months, Modified enamel decalcification index (Cronan 2012)

Specificity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted… · Up to 3 months between index test and reference standard (in vivo studies), Reference standard: histology (non-CBCT)

Radiographic proximal caries lesion progression · Patients with non-cavitated proximal caries lesions · Longest available follow-up, Caries risk: low to moderate

Diagnostic accuracy for proximal caries detection (dentin detection level) · Patients with permanent posterior teeth, proximal surfaces assessed clinically (in vivo) · Dentin detection level

Water samples with fluoride concentration below the acceptable range · Artificially fluoridated public water supply in Brazilian cities (water samples under external control) · Region: Southeast Brazil

Dental caries prevalence · Arab children with special health care needs in Ras Al Khaimah · Overall

Specificity for detection of enamel caries · Asymptomatic children or adults presenting for clinical examination (in vivo studies), or extracted teeth of children… · Up to 3 months between index test and reference standard (in vivo studies), Permanent dentition

New dental caries development · Onabotulinumtoxin A open-label, no control (Møller 2015)

S. mutans counts (5th-root transformed) · Adolescents/teenagers undergoing orthodontic treatment · 1 month, Adolescents

Diagnostic accuracy for occlusal caries detection at the 1/3 dentin caries detection level (Ekstrand; D0-2 versus D3-4) · Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces

Failure of therapy · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious… · 30 months, Cavitated lesions, primary dentition

Mean DMFT · School children aged 11-17 years in Sharjah · Overall

Streptococcus mutans load in the oral cavity (saliva and/or dental plaque) · Adults and children (general population) · Final/end-of-study time point (follow-up 2 weeks to 18 months), Overall (vs all controls)

Failure of therapy · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious… · 30 months, Cavitated lesions, primary dentition

Dental caries prevalence · General population (children and adults) in East Africa · Tanzania