Search review questions

Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) · Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces

Sensitivity · Children, adolescents, or adults presenting asymptomatically or suspected of early enamel caries (in vivo), or… · Up to 3 months between index test and reference standard (in vivo studies), Primary dentition

Initiation of white spot lesions (WSL), visual-tactile assessment · Sensitivity (coating with vs without fluoride release, excluding high risk-of-bias studies)

Dental caries (presence) · Individuals in East Africa assessed for dental caries

Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) · Human permanent posterior teeth (premolars and molars) in patients, occlusal (pit-and-fissure) surfaces

Iron deficiency (ID) · Preschool children (<6 years) · Overall

Dental caries prevalence · Preschoolers (AlKhayat, Dubai private preschools)

Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) · Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces

Dental erosion · Five-year-old preschool children in Sharjah · Overall

Diagnostic accuracy for occlusal caries detection at the 1/3 dentin caries detection level (Ekstrand; D0-2 versus D3-4) · Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces

Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) · Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces

Dental information from relatives · Mothers of preschool children in Sharjah · Overall

Mean dmft · Emirati preschool children in Ras Al Khaimah nurseries · Overall

Efficiency, costs or cost-effectiveness · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious… · Primary dentition

Locoregional control, chemotherapy regimen A vs regimen B · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer

Clinical evaluation of restoration's quality · Dental patients undergoing direct or indirect restorative treatment (no age or gender restriction) · 6, 12, 18 months, Non-carious cervical lesions (composite restoration)

Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Overall

Sensitivity for detection of enamel caries · Asymptomatic children or adults presenting for clinical examination (in vivo studies), or extracted teeth of children… · Up to 3 months between index test and reference standard (in vivo studies)

Sensitivity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted… · Up to 3 months between index test and reference standard (in vivo studies), Reference standard: histology (non-CBCT)

Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) · Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces

Outcome NR · Samples with a low (<15%) prevalence of caries into dentine (d3/D3); target condition = non-cavitated enamel caries. · Up to 3 months between index test and reference standard (in vivo studies)

Lesion area (decalcification area, pixels) · Adults undergoing orthodontic treatment · 3 months, Adults

Diagnostic accuracy for proximal caries detection (dentin detection level) · Patients with permanent posterior teeth, proximal surfaces assessed clinically (in vivo) · Dentin detection level

Survival rate of restorations (12 months) · Dental patients undergoing direct or indirect restorative treatment (no age or gender restriction) · 12 months, Non-carious cervical lesions (composite restoration)

Dental caries prevalence · Emirati preschool children in Ras Al Khaimah nurseries · Overall

Participant acceptance/satisfaction · Dental patients undergoing direct or indirect restorative treatment (no age or gender restriction) · Non-carious cervical lesions (composite restoration)

Diagnostic accuracy for proximal caries detection (dentin detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro) · Dentin detection level

Diagnostic accuracy for proximal caries detection (1/3 dentin detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro) · 1/3 dentin detection level

Dental caries susceptibility (risk of dental caries) · Children and adults (no age limit) assessed for dental caries susceptibility · Ethnicity: Asian

Dental caries · Healthy children and adolescents in the United Arab Emirates

Overall survival, concurrent chemoradiotherapy vs radiotherapy alone (pooled) · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer

Unhealthy gums/gingivitis in all oral regions · School children aged 11-17 years in Sharjah · Overall

Difference in sensitivity · Children or adults asymptomatic or suspected of enamel caries; extracted teeth · Analysis 1: fully within-person comparison

Specificity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted… · Up to 3 months between index test and reference standard (in vivo studies), Occlusal surfaces (CBCT)

Sensitivity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted… · Up to 3 months between index test and reference standard (in vivo studies)

Initiation of white spot lesions (WSL), visual-tactile assessment · Patients of any age (11-40 years) receiving comprehensive/fixed orthodontic treatment with fixed appliances · 1-24 months follow-up

Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) · Human permanent posterior teeth (premolars and molars) in patients, occlusal (pit-and-fissure) surfaces

Masking effect (esthetic improvement) · Patients with dental fluorosis

Failure of therapy · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious… · 12 months, Deep lesions, primary dentition

Dental caries · Healthy children and adolescents in the United Arab Emirates

Diagnostic accuracy for proximal caries detection · Permanent posterior teeth, proximal surfaces (in vitro extracted teeth and in vivo patients)

Lesion progression · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious… · Non-cavitated lesions, permanent dentition

Radiographic proximal caries lesion progression · Patients with non-cavitated proximal (approximal) caries lesions (primary or permanent dentition) · Longest available follow-up, Permanent dentition

Diagnostic accuracy for proximal caries detection (dentin detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro) · Dentin detection level

Tooth brushing less than once daily, females in 2016 · Nationally surveyed adolescents in the United Arab Emirates · Overall

Sensitivity (COE alone arm) · OSCC or OPMD symptom-free individuals with tobacco habits

Dental caries · Children

Survival rate of the restorations · Dental patients undergoing restorative treatment (no age or gender restriction)

Failure of therapy · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious… · 12-24 months, Deep lesions, primary dentition

Sensitivity (COE plus vital rinsing arm) · OSCC or OPMD symptom-free individuals with tobacco habits