Irinotecan, docetaxel, paclitaxel, vinorelbine, ganciclovir, epirubicin, multiple drugsϯ · healthcare staff who handle infusional hazardous drugs
It is very uncertain whether closed‐system transfer device plus safe handling changes irinotecan, docetaxel, paclitaxel, vinorelbine, ganciclovir,… compared with safe handling alone (very low certainty).
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
5‐fluorouracil, cytarabine, gemcitabine, irinotecan, docetaxel, paclitaxel, vinorelbine, multiple drugsϯ · healthcare staff who handle infusional hazardous drugs
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Cytarabine, gemcitabine, and irinotecan · healthcare staff who handle infusional hazardous drugs
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
5‐fluorouracil, cytarabine, gemcitabine, and irinotecan · healthcare staff who handle infusional hazardous drugs
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Death or use of ECMO; studies that did not allow back‐up use of iNO in controls · respiratory failure in infants born at or near term
Inhaled NO leads to lower death or use of ECMO; studies that did not allow back‐up use of iNO… compared with control (high certainty).
1 finding from 1 review
Death at hospital discharge · respiratory failure in infants born at or near term
Inhaled NO showed no clear difference in death before hospital discharge; studies that did not allow back‐up… compared with control (high certainty).
1 finding from 1 review
Use of ECMO before hospital discharge · respiratory failure in infants born at or near term
Inhaled NO leads to lower use of ECMO before hospital discharge; studies that did not allow… compared with control (high certainty).
1 finding from 1 review
Minor bleeding · people with coronary disease, ischaemic cerebrovascular disease, peripheral arterial disease or at high risk of atherothrombotic disease
clopidogrel plus aspirin probably leads to higher minor bleeding compared with aspirin alone (moderate certainty).
1 finding from 1 review
Minor bleeding
Heparin prophylaxis leads to higher minor bleeding compared with no prophylaxis (high certainty).
1 finding from 1 review
Vitamin A deficiency · mortality and morbidity in term neonates
Neonatal vitamin A supplementation showed no clear difference in vitamin A deficiency (serum retinol < 0.70 micromol/L) at 6 weeks of… compared with control (high certainty).
2 findings from 1 review
Six‐minute walk distance · people with stroke
1 finding from 1 review
Intervention not reported
Entomological inoculation rate · people living in malaria‐endemic areas
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Minor complications (3 to 6 weeks · patients with sigmoid diverticulitis
1 finding from 1 review
Adverse event ‐ rhinorrhoea · infants and children
Influenza vaccine may leads to higher rhinorrhoea compared with control (low certainty).
1 finding from 1 review
Intervention not reported
Retinopathy of prematurity requiring treatment · extremely preterm infants
The intervention probably leads to lower retinopathy of prematurity requiring treatment (moderate certainty).
1 finding from 1 review
Cholangiocarcinoma · people with primary sclerosing cholangitis
It is very uncertain whether ursodeoxycholic acid changes cholangiocarcinoma compared with placebo (very low certainty).
1 finding from 1 review
Minor bleeding · atrial fibrillation patients with CKD
Direct oral anticoagulants (DOAC) showed no clear difference in minor bleeding compared with warfarin (low certainty).
1 finding from 1 review
Retinopathy of prematurity, any or severe (stage ≥ III) · patients with preventing morbidity and mortality in very preterm infants
It is very uncertain whether cerebral NIRS oximetry changes retinopathy of prematurity, any or severe (stage ≥ III) compared with no cerebral NIRS oximetry (very low certainty).
1 finding from 1 review
Bleeding (major and minor) · participants at risk of venous thromboembolism
1 finding from 1 review
Bleeding (major and minor) · participants at risk of venous thromboembolism
1 finding from 1 review