Cochrane · systematic review · CD011764

Neuromuscular electrical stimulation for the prevention of venous thromboembolism

Hajibandeh, S, Hajibandeh, S, Antoniou, GA, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library

VascularAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
48
current version
GRADE rated
22
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 26 · 54.2%Very low 0 · 0%Low 21 · 43.8%Moderate 1 · 2.1%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

NMES compared to alternative prophylaxis for the prevention of venous thromboembolism

Population: participants at risk of venous thromboembolism
6 questions
OutcomeEffectEvidenceStatus / GRADE
Total DVT
NMES vs alternative prophylaxis
OR 1.01 [0.6, 1.7]6 studies · 415 participantsLow
Downgraded: risk of bias, inconsistency
Asymptomatic DVT
NMES vs alternative prophylaxis
OR 1.61 [0.4, 6.43]1 study · 89 participantsLow
Downgraded: risk of bias, imprecision
Symptomatic DVT
NMES vs alternative prophylaxis
OR 0.4 [0.02, 10.07]1 study · 89 participantsLow
Downgraded: risk of bias, imprecision
PE
NMES vs alternative prophylaxis
OR 1.31 [0.38, 4.48]2 studies · 126 participantsLow
Downgraded: risk of bias, imprecision
Total VTE
NMES vs alternative prophylaxis
OR 0.92 [0.34, 2.52]1 study · 72 participantsLow
Downgraded: risk of bias, imprecision
Bleeding (major and minor)
NMES vs alternative prophylaxis
no estimate extracted6 studies · 415 participantsUngraded

NMES compared to no prophylaxis for prevention of venous thromboembolism

Population: participants at risk of venous thromboembolism
6 questions
OutcomeEffectEvidenceStatus / GRADE
Total DVT
NMES vs no prophylaxis
OR 0.4 [0.23, 0.7]4 studies · 576 participantsModerate
Downgraded: risk of bias
Asymptomatic DVT
NMES vs no prophylaxis
OR 0.32 [0.06, 1.62]1 study · 200 participantsLow
Downgraded: risk of bias, imprecision
Symptomatic DVT
NMES vs no prophylaxis
OR 0.06 [0, 1.36]1 study · 160 participantsLow
Downgraded: risk of bias, imprecision
PE
NMES vs no prophylaxis
OR 0.36 [0.12, 1.07]1 study · 77 participantsLow
Downgraded: risk of bias, imprecision
Total VTE
NMES vs no prophylaxis
OR 0.23 [0.09, 0.59]1 study · 77 participantsLow
Downgraded: risk of bias, imprecision
Bleeding (major and minor)
NMES vs no prophylaxis
no estimate extracted4 studies · 576 participantsUngraded

NMES compared to low‐dose heparin for the prevention of venous thromboembolism

Population: participants at risk of venous thromboembolism
6 questions
OutcomeEffectEvidenceStatus / GRADE
Total DVT
NMES vs low‐dose heparin
OR 2.78 [1.19, 6.48]2 studies · 194 participantsLow
Downgraded: risk of bias, imprecision
Asymptomatic DVT
NMES vs low‐dose heparin
OR 1.61 [0.4, 6.43]1 study · 89 participantsLow
Downgraded: risk of bias, imprecision
Symptomatic DVT
NMES vs low‐dose heparin
OR 0.4 [0.02, 10.07]1 study · 89 participantsLow
Downgraded: risk of bias, imprecision
PE
NMES vs low‐dose heparin
no estimate extracted2 studies · 194 participantsUngraded
Total VTE
NMES vs low‐dose heparin
no estimate extracted2 studies · 194 participantsUngraded
Bleeding (major and minor)
NMES vs low‐dose heparin
no estimate extracted2 studies · 194 participantsUngraded

NMES compared to Dextran 40 for the prevention of venous thromboembolism

Population: participants at risk of venous thromboembolism
6 questions
OutcomeEffectEvidenceStatus / GRADE
Total DVT
NMES vs Dextran 40
OR 0.63 [0.18, 2.19]1 study · 72 participantsLow
Downgraded: risk of bias, imprecision
Asymptomatic DVT
NMES vs Dextran 40
no estimate extracted1 study · 72 participantsUngraded
Symptomatic DVT
NMES vs Dextran 40
no estimate extracted1 study · 72 participantsUngraded
PE
NMES vs Dextran 40
OR 1.5 [0.39, 5.84]1 study · 72 participantsLow
Downgraded: risk of bias, imprecision
Total VTE
NMES vs Dextran 40
OR 0.92 [0.34, 2.52]1 study · 72 participantsLow
Downgraded: risk of bias, imprecision
Bleeding (major and minor)
NMES vs Dextran 40
no estimate extracted1 study · 72 participantsUngraded

Combined NMES and low‐dose heparin compared to no prophylaxis for the prevention of venous thromboembolism

Population: participants at risk of venous thromboembolism
6 questions
OutcomeEffectEvidenceStatus / GRADE
Total DVT
Combined NMES and low‐dose heparin vs no prophylaxis
OR 0.08 [0.01, 0.76]1 study · 32 participantsLow
Downgraded: risk of bias, imprecision
Asymptomatic DVT
Combined NMES and low‐dose heparin vs no prophylaxis
no estimate extracted1 study · 32 participantsUngraded
Symptomatic DVT
Combined NMES and low‐dose heparin vs no prophylaxis
no estimate extracted1 study · 32 participantsUngraded
PE
Combined NMES and low‐dose heparin vs no prophylaxis
no estimate extracted1 study · 32 participantsUngraded
Total VTE
Combined NMES and low‐dose heparin vs no prophylaxis
no estimate extracted1 study · 32 participantsUngraded
Bleeding (major and minor)
Combined NMES and low‐dose heparin vs no prophylaxis
no estimate extracted1 study · 32 participantsUngraded

Combined NMES and low‐dose heparin compared to low‐dose heparin for the prevention of venous thromboembolism

Population: participants at risk of venous thromboembolism
6 questions
OutcomeEffectEvidenceStatus / GRADE
Total DVT
Combined NMES and low‐dose heparin vs low‐dose heparin
OR 0.07 [0.01, 0.68]1 study · 31 participantsLow
Downgraded: risk of bias, imprecision
Asymptomatic DVT
Combined NMES and low‐dose heparin vs low‐dose heparin
no estimate extracted1 study · 31 participantsUngraded
Symptomatic DVT
Combined NMES and low‐dose heparin vs low‐dose heparin
no estimate extracted1 study · 31 participantsUngraded
PE
Combined NMES and low‐dose heparin vs low‐dose heparin
no estimate extracted1 study · 31 participantsUngraded
Total VTE
Combined NMES and low‐dose heparin vs low‐dose heparin
no estimate extracted1 study · 31 participantsUngraded
Bleeding (major and minor)
Combined NMES and low‐dose heparin vs low‐dose heparin
no estimate extracted1 study · 31 participantsUngraded

NMES compared to GCS for the prevention of venous thromboembolism

Population: participants at risk of venous thromboembolism
6 questions
OutcomeEffectEvidenceStatus / GRADE
Total DVT
NMES vs GCS
OR 0.32 [0.01, 8.27]1 study · 36 participantsLow
Downgraded: risk of bias, imprecision
Asymptomatic DVT
NMES vs GCS
no estimate extracted1 study · 36 participantsUngraded
Symptomatic DVT
NMES vs GCS
no estimate extracted1 study · 36 participantsUngraded
PE
NMES vs GCS
OR 0.32 [0.01, 8.27]1 study · 36 participantsLow
Downgraded: risk of bias, imprecision
Total VTE
NMES vs GCS
no estimate extracted1 study · 36 participantsUngraded
Bleeding (major and minor)
NMES vs GCS
no estimate extracted1 study · 36 participantsUngraded

NMES compared to IPCD for the prevention of venous thromboembolism

Population: participants at risk of venous thromboembolism
6 questions
OutcomeEffectEvidenceStatus / GRADE
Total DVT
NMES vs IPCD
no estimate extracted1 study · 36 participantsLow
Downgraded: risk of bias, imprecision
Asymptomatic DVT
NMES vs IPCD
no estimate extracted1 study · 36 participantsUngraded
Symptomatic DVT
NMES vs IPCD
no estimate extracted1 study · 36 participantsUngraded
PE
NMES vs IPCD
no estimate extracted1 study · 36 participantsLow
Downgraded: risk of bias, imprecision
Total VTE
NMES vs IPCD
no estimate extracted1 study · 36 participantsUngraded
Bleeding (major and minor)
NMES vs IPCD
no estimate extracted1 study · 36 participantsUngraded