Postoperative endoscopic appearance of the sinonasal surgical cavities: Lund‐Kennedy endoscopic score (range 1 to 10) · adult patients who underwent primary endoscopic sinus surgery, with a diagnosis of recurrent acute or chronic rhinosinusitis
Sinonasal debridement showed no clear difference in postoperative endoscopic appearance of the sinonasal surgical… compared with no debridement (low certainty).
1 finding from 1 review
Number of minor postoperative bleeding episodes · People with haemophilia (A or B) undergoing minor oral surgery or dental extractions
The review found no eligible studies for this question.
1 finding from 1 review
Number of minor postoperative bleeding episodes · People on continuous VKA treatment undergoing minor oral surgery or dental extractions (eligibility included DOACs and all ages; all four…
Antifibrinolytic therapy - locally-applied tranexamic acid (TXA)… showed no clear difference in number of minor postoperative bleeding episodes compared with placebo (placebo solution/mouthwash); GRADE not reported.
1 finding from 1 review
Bleeding duration (minutes, all types of bleeding, minor and major) · People on continuous VKA treatment undergoing minor oral surgery or dental extractions (eligibility included DOACs and all ages; all four…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Overall treatment failure, including mortality, thoracic surgery or referral for further fibrinolytic therapy · adult parapneumonic effusions and empyema
It is very uncertain whether fibrinolytics changes overall treatment failure, including mortality, thoracic surgery or… compared with placebo (very low certainty).
1 finding from 1 review
Survival to hospital discharge · participants with bradyasystolic cardiac arrest in adults
Aminophylline showed no clear difference in survival to hospital discharge compared with placebo (moderate certainty).
2 findings from 1 review
Return of spontaneous circulation · participants with bradyasystolic cardiac arrest in adults
Aminophylline showed no clear difference in return of spontaneous circulation compared with placebo (high certainty).
2 findings from 1 review
Early administration of aminophylline: survival to hospital admission · participants with bradyasystolic cardiac arrest in adults
Aminophylline showed no clear difference in survival to admission compared with placebo (moderate certainty).
2 findings from 1 review
Minor adverse events · people with active UC
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Quality of life Drug resistance/microbial sensitivity Serious adverse events Lung function Hospitalisations Adverse events/side effects Number of participants colonised with P aeruginosa · patients with chronic obstructive pulmonary disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Exacerbations (number of people experiencing ≥ 1 exacerbations) · patients with chronic obstructive pulmonary disease
Quinolone showed no clear difference in number of participants experiencing one or more exacerbations… compared with tetracycline (low certainty).
1 finding from 1 review
Quality of life Drug resistance/microbial sensitivity Serious adverse events Lung function Hospitalisations Adverse events/side effects Number of participants colonised with P aeruginosa · patients with chronic obstructive pulmonary disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Exacerbations (number of people experiencing ≥ 1 exacerbations) · patients with chronic obstructive pulmonary disease
Quinolone showed no clear difference in number of participants experiencing one or more exacerbations… compared with macrolide (low certainty).
1 finding from 1 review
Adverse events of antifibrinolytic agents · People with a haematological disorder
1 finding from 1 review
Overall mortality · critically ill participants with ALI and ARDS
INO showed no clear difference in overall mortality compared with control group (moderate certainty).
1 finding from 1 review
Overall mortality at 28 days · critically ill participants with ALI and ARDS
INO showed no clear difference in overall mortality at 28 days compared with control group (moderate certainty).
1 finding from 1 review
Mortality in paediatric population (subgroup) · critically ill participants with ALI and ARDS
INO showed no clear difference in mortality in paediatric population (subgroup) compared with control group (moderate certainty).
1 finding from 1 review
RR 0.78 [0.51, 1.18]
185 participants
Moderate
Respiratory effects: PaO2/FiO2 ratio up to 24 hours after initiation of therapy · critically ill participants with ALI and ARDS
INO probably leads to higher paO2/FiO2 up to 24 hours compared with control group (moderate certainty).
1 finding from 1 review
Oxygenation index (absolute values) after 24 hours of treatment · critically ill participants with ALI and ARDS
INO showed no clear difference in oxygenation index, 24 hours compared with control group (moderate certainty).
1 finding from 1 review
Ventilator‐free days up to day 28 · critically ill participants with ALI and ARDS
INO showed no clear difference in ventilation‐free days, up to 30 days compared with control group (high certainty).
1 finding from 1 review