Question · asked by 1 review

INO vs control group: Overall mortality at 28 days

INO showed no clear difference in overall mortality at 28 days compared with control group (moderate certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
INO vs control group
Overall mortality at 28 days · critically ill participants with ALI and ARDS
INO showed no clear difference in overall mortality at 28 days compared with control group (moderate certainty).
Inhaled nitric oxide for acute respiratory distress syndrome (ARDS) in children and adults (2016) · Cochrane Headline outcomes only
RR 1.08 [0.92, 1.27]9 studies · 1105 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Inhaled nitric oxide for acute respiratory distress syndrome (ARDS) in children and adults
2016 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.