INO vs control group: Respiratory effects: PaO2/FiO2 ratio up to 24 hours after initiation of therapy
INO probably leads to higher paO2/FiO2 up to 24 hours compared with control group (moderate certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
INO vs control group PaO2/FiO2 up to 24 hours · critically ill participants with ALI and ARDS INO probably leads to higher paO2/FiO2 up to 24 hours compared with control group (moderate certainty). Inhaled nitric oxide for acute respiratory distress syndrome (ARDS) in children and adults (2016) · Cochrane Headline outcomes only | MD 15.91 [8.25, 23.56] | 11 studies · 614 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Inhaled nitric oxide for acute respiratory distress syndrome (ARDS) in children and adults 2016 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.