Question · asked by 1 review

Aminophylline vs placebo: Early administration of aminophylline: survival to hospital admission

Aminophylline showed no clear difference in survival to admission compared with placebo (moderate certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Aminophylline vs placebo
Survival to admission · participants with bradyasystolic cardiac arrest in adults
Aminophylline showed no clear difference in survival to admission compared with placebo (moderate certainty).
Aminophylline for bradyasystolic cardiac arrest in adults (2015) · Cochrane Headline outcomes only
OR 0.92 [0.61, 1.39]4 studies · 1232 participantsModerate
Aminophylline vs placebo
Early administration of aminophylline: survival to hospital admission · participants with bradyasystolic cardiac arrest in adults
Aminophylline showed no clear difference in early administration of aminophylline: survival to hospital admission compared with placebo (low certainty).
Aminophylline for bradyasystolic cardiac arrest in adults (2015) · Cochrane Headline outcomes only
OR 0.22 [0.02, 2.36]2 studies · 37 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Aminophylline for bradyasystolic cardiac arrest in adults
2015 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.