Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,908 questions · 3,101 findings · 509 reviews

No studies found 571 · 18.4%GRADE not reported 358 · 11.5%Very low 723 · 23.3%Low 854 · 27.5%Moderate 489 · 15.8%High 106 · 3.4%

Edaravone plus corticosteroids vs corticosteroids

Reduction in oedema (T2 hyperintensity) · people previously treated with radiosurgery or fractionated radiotherapy to the brain or head and neck region with a diagnosis of brain…

Edaravone plus corticosteroids showed no clear difference in reduction in oedema (T2 hyperintensity) compared with corticosteroids (low certainty).

1 finding from 1 review

Systemic administration of beta‐blockers vs placebo or no treatment

Arterial hypotension and/or bradycardia requiring treatment · Prevention of retinopathy of prematurity in preterm infants

Systemic administration of beta‐blockers may leads to higher arterial hypotension and/or bradycardia requiring treatment compared with placebo or no treatment (low certainty).

1 finding from 1 review

Summary of findings: feedback on medication adherence to physicians vs usual care

Processes of care Rate of medication change (medication discontinued, added, replaced), proportion of visits with appropriate management of uncontrolled hypertension, patient rating (quality of care, duration of the visit, communication with physi... · any physician, and any patient treated for chronic diseases with long‐term medication use
1 finding from 1 review

Local anaesthetic injection vs no treatment/placebo

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · septal surgery

The review found no eligible studies for this question.

3 findings from 1 review

Sphenopalatine ganglion block vs no treatment/placebo

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · septal surgery

The review found no eligible studies for this question.

3 findings from 1 review

Activity monitor plus other intervention vs other intervention alone

Time spent in light intensity activity (minutes) at the end of the intervention (> 6 months post‐stroke) ‐ not reported · increasing physical activity in adult community dwelling stroke survivors

The review found no eligible studies for this question.

1 finding from 1 review

Activity monitor plus other intervention vs other intervention alone

Time spent on light intensity physical activity (minutes) at the end of the intervention (< 6 months post‐stroke) (Time spent on light intensity physical activity (minutes) ) · increasing physical activity in adult stroke survivors during inpatient rehabilitation
1 finding from 1 review