Cochrane · systematic review · CD012047

Perioperative local anaesthesia for reducing pain following septal surgery

Fujiwara, T, Kuriyama, A, Kato, Y, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library

ENTAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
21
current version
GRADE rated
4
No studies
17
Included studies
NR
No studies 17 · 81%Ungraded 0 · 0%Very low 1 · 4.8%Low 2 · 9.5%Moderate 1 · 4.8%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Local anaesthetic injection compared to no treatment/placebo in septal surgery

Population: septal surgery
7 questions
OutcomeEffectEvidenceStatus / GRADE
Pain intensity at 12 hours postoperatively ‐ not reported
Local anaesthetic injection vs no treatment/placebo
no estimate extractedNRNo studies
Pain intensity at 24 hours postoperatively ‐ not reported
Local anaesthetic injection vs no treatment/placebo
no estimate extractedNRNo studies
Pain intensity at 48 hours postoperatively ‐ not reported
Local anaesthetic injection vs no treatment/placebo
no estimate extractedNRNo studies
Requirement for additional analgesia
Local anaesthetic injection vs no treatment/placebo
no estimate extractedNRNo studies
Duration of hospitalisation ‐ not reported
Local anaesthetic injection vs no treatment/placebo
no estimate extractedNRNo studies
Adverse effect (postoperative vomiting)
Local anaesthetic injection vs no treatment/placebo
OR 3.1 [0.12, 79.23]1 study · 60 participantsLow
Downgraded: imprecision
Adverse effect (postoperative bleeding) ‐ not reported
Local anaesthetic injection vs no treatment/placebo
no estimate extractedNRNo studies

Local anaesthetic application via nasal packing compared to no packing/packing with placebo

Population: septal surgery
7 questions
OutcomeEffectEvidenceStatus / GRADE
Pain intensity at 12 hours postoperatively
Local anaesthetic application via nasal packing vs no packing/packing with placebo
no estimate extracted2 studies · 151 participantsLow
Downgraded: risk of bias
Pain intensity at 24 hours postoperatively
Local anaesthetic application via nasal packing vs no packing/packing with placebo
no estimate extracted4 studies · 268 participantsVery low
Downgraded: risk of bias, inconsistency
Pain intensity at 48 hours postoperatively ‐ not reported
Local anaesthetic application via nasal packing vs no packing/packing with placebo
no estimate extractedNRNo studies
Requirement for additional analgesia
Local anaesthetic application via nasal packing vs no packing/packing with placebo
OR 0.15 [0.07, 0.34]2 studies · 151 participantsModerate
Downgraded: risk of bias, inconsistency
Duration of hospitalisation ‐ not reported
Local anaesthetic application via nasal packing vs no packing/packing with placebo
no estimate extractedNRNo studies
Adverse effect (postoperative vomiting) ‐ not reported
Local anaesthetic application via nasal packing vs no packing/packing with placebo
no estimate extractedNRNo studies
Adverse effect (postoperative bleeding) ‐ not reported
Local anaesthetic application via nasal packing vs no packing/packing with placebo
no estimate extractedNRNo studies

Sphenopalatine ganglion block compared to no treatment/placebo in septal surgery

Population: septal surgery
7 questions
OutcomeEffectEvidenceStatus / GRADE
Pain intensity at 12 hours postoperatively ‐ not reported
Sphenopalatine ganglion block vs no treatment/placebo
no estimate extractedNRNo studies
Pain intensity at 24 hours postoperatively ‐ not reported
Sphenopalatine ganglion block vs no treatment/placebo
no estimate extractedNRNo studies
Pain intensity at 48 hours postoperatively ‐ not reported
Sphenopalatine ganglion block vs no treatment/placebo
no estimate extractedNRNo studies
Requirement for additional analgesia
Sphenopalatine ganglion block vs no treatment/placebo
no estimate extractedNRNo studies
Duration of hospitalisation ‐ not reported
Sphenopalatine ganglion block vs no treatment/placebo
no estimate extractedNRNo studies
Adverse effect (postoperative vomiting) ‐ not reported
Sphenopalatine ganglion block vs no treatment/placebo
no estimate extractedNRNo studies
Adverse effect (postoperative bleeding) ‐ not reported
Sphenopalatine ganglion block vs no treatment/placebo
no estimate extractedNRNo studies