Abnormal Vaginal Bleeding or Spotting · pelvic organ prolapse in women
Pessary plus PFMT showed no clear difference in number of women with adverse events ‐ abnormal vaginal bleeding compared with pelvic floor muscle training (PFMT) alone (low certainty).
1 finding from 1 review
Intervention not reported
Cranial ultrasound abnormalities ‒intraventricular haemorrhage grade 3 to 4 · infants below 33 weeks of postmenstrual age who required resuscitation in the delivery room
It is very uncertain whether the intervention changes cranial ultrasound abnormalities ‒intraventricular haemorrhage grade… (very low certainty).
1 finding from 1 review
RR 0.4 [0.05, 2.98]
1 study · 9 participants
Very low
Intraventricular haemorrhage, Papile grade 3/4 · preterm infants resuscitated by PPV at birth
Use of initial sustained inflation showed no clear difference in cranial ultrasound abnormalities ‒Intraventricular haemorrhage grade… compared with standard inflations (low certainty).
1 finding from 1 review
Intervention not reported
Abnormal intracranial pressure · adults with traumatic brain injury
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Abnormal Vaginal Bleeding or Spotting · endometrial protection in women with breast cancer on adjuvant tamoxifen
The LNG‐IUS with endometrial surveillance probably leads to higher abnormal vaginal bleeding or spotting compared with endometrial surveillance alone (moderate certainty).
1 finding from 1 review
Adverse effects: abnormal vision Duration of treatment (range): 8–36 weeks · people (aged 10–64 years) with drug‐resistant focal epilepsy
It is very uncertain whether vigabatrin changes adverse effects: abnormal vision Duration of treatment (range): 8–36… compared with placebo (very low certainty).
1 finding from 1 review
Uterine fibroid‐related symptoms (abnormal uterine bleeding, measured at 12 weeks, with the pictorial blood assessment chart (PBAC); lower = better) · women with uterine fibroids
2 findings from 1 review
Uterine fibroid‐related symptoms (abnormal uterine bleeding, measured at 12 weeks, with the pictorial blood assessment chart (PBAC); lower = better) · women with uterine fibroids
1 finding from 1 review
Change in fibroid related symptoms · women with uterine fibroids
1 finding from 1 review
Intervention not reported
Congenital abnormalities per live birth · couples undergoing assisted reproduction treatment
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Foetal abnormalities · Subfertile women undergoing assisted reproduction
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Foetal abnormalities · Subfertile women undergoing assisted reproduction
Embryo culture supernatant injection showed no clear difference in foetal abnormalities compared with no intervention (low certainty).
1 finding from 1 review
Adverse effects ‐ 'thinking abnormally' · people with drug‐resistant focal epilepsy
Topiramate leads to higher adverse effects ‐ 'thinking abnormally' compared with placebo (high certainty).
1 finding from 1 review
Total new and progressive Renal parenchymal abnormalities on DMSA scan at 1 to 2 years: endoscopic correction + antibiotics versus antibiotics alone (unit of analysis: children) · primary VUR
Endoscopic injection treatment showed no clear difference in total new and progressive Renal parenchymal abnormalities on DMSA… compared with antibiotics alone (low certainty).
1 finding from 1 review
Incidence of coronary artery abnormalities · children diagnosed with Kawasaki disease
TNF‐α blockers intervention showed no clear difference in incidence of coronary artery abnormalities compared with placebo or additional treatment (low certainty).
1 finding from 1 review
Intervention not reported
Adverse effects Defined as deaths, hospitalisations, congenital abnormalities and life‐threatening conditions requiring an immediate hospital visit Assessed at 12 and 18 months of age · children aged 6 to 23 months
The intervention showed no clear difference in adverse effects Defined as deaths, hospitalisations, congenital… (moderate certainty).
1 finding from 1 review
Liver toxicity: number experiencing abnormal liver function tests 24 weeks · Patients with osteoarthritis of the knee or hip
Paracetamol probably leads to higher liver toxicity: number experiencing abnormal liver function tests 24… compared with placebo (moderate certainty).
1 finding from 1 review
Congential abnormalities · women with threatened miscarriage
It is very uncertain whether progesterone changes congential abnormalities compared with placebo or no treatment (very low certainty).
1 finding from 1 review
Abnormal blood urea nitrogen (various criteria) · preterm infants
Higher leads to higher abnormal blood urea nitrogen (various criteria) compared with lower amino acid intake (high certainty).
1 finding from 1 review
Abnormal fetal heart rate patterns, requiring intervention · women in the second stage of labour with epidural anaesthesia
It is very uncertain whether upright position changes abnormal fetal heart rate patterns, requiring intervention compared with recumbent position (very low certainty).
1 finding from 1 review