Cochrane · systematic review · CD004010
Pessaries (mechanical devices) for managing pelvic organ prolapse in women
Bugge, C, Adams, EJ, Gopinath, D, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
19
current version
GRADE rated
10
No studies
9
Included studies
NR
No studies 9 · 47.4%Ungraded 0 · 0%Very low 2 · 10.5%Low 6 · 31.6%Moderate 2 · 10.5%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Show all 2 versionsAny pessary compared to control, waiting list or no active treatment
Population: pelvic organ prolapse in women
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Perceived resolution of prolapse symptoms: ≥ 12 months Any pessary vs control, waiting list or no active treatment | no estimate extracted | NR | No studies |
Perceived improvement of prolapse symptoms (higher score = worse symptoms) Any pessary vs control, waiting list or no active treatment | no estimate extracted | 1 study · 27 participants | Very low Downgraded: risk of bias |
Prolapse‐specific quality of life ≥ 12 months Any pessary vs control, waiting list or no active treatment | no estimate extracted | NR | No studies |
Cure or improvement of sexual problems Any pessary vs control, waiting list or no active treatment | no estimate extracted | 1 study · 27 participants | Very low Downgraded: risk of bias |
Psychological outcome measures at ≥ 12 months Any pessary vs control, waiting list or no active treatment | no estimate extracted | NR | No studies |
Number of women with adverse events (vaginal bleeding, voiding difficulty) Any pessary vs control, waiting list or no active treatment | no estimate extracted | NR | No studies |
Any pessary compared to pelvic floor muscle training (PFMT) for pelvic organ prolapse in women
Population: pelvic organ prolapse in women
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Perceived resolution of prolapse symptoms ≥ 12 months Any pessary vs pelvic floor muscle training (PFMT) | no estimate extracted | NR | No studies |
Women's perceived improvement of prolapse symptoms (higher score = worse symptoms) Any pessary vs pelvic floor muscle training (PFMT) | no estimate extracted | 1 study · 117 participants | Low Downgraded: imprecision |
Prolapse‐specific quality of life (higher score = worse QoL) Any pessary vs pelvic floor muscle training (PFMT) | no estimate extracted | 1 study · 116 participants | Low Downgraded: imprecision |
Cure or improvement of sexual problems (higher score = better sexual functioning) Any pessary vs pelvic floor muscle training (PFMT) | no estimate extracted | 1 study · 48 participants | Low Downgraded: imprecision |
Psychological outcome measures at ≥ 12 months Any pessary vs pelvic floor muscle training (PFMT) | no estimate extracted | NR | No studies |
Number of women with adverse events Any pessary vs pelvic floor muscle training (PFMT) | RR 75.25 [4.7, 1205.45] | 1 study · 97 participants | Low Downgraded: imprecision |
Pessary plus PFMT compared to pelvic floor muscle training (PFMT) alone for pelvic organ prolapse in women
Population: pelvic organ prolapse in women
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Perceived resolution of prolapse symptoms ≥ 12 months Pessary plus PFMT vs pelvic floor muscle training (PFMT) alone | no estimate extracted | NR | No studies |
Perceived improvement of prolapse symptoms Pessary plus PFMT vs pelvic floor muscle training (PFMT) alone | RR 2.15 [1.58, 2.94] | 1 study · 260 participants | Moderate Downgraded: imprecision |
Prolapse‐specific quality of life Pessary plus PFMT vs pelvic floor muscle training (PFMT) alone | no estimate extracted | 1 study · 260 participants | Moderate Downgraded: imprecision |
Cure or improvement of sexual problems ≥ 12 months Pessary plus PFMT vs pelvic floor muscle training (PFMT) alone | no estimate extracted | NR | No studies |
Psychological outcome measures at ≥ 12 months Pessary plus PFMT vs pelvic floor muscle training (PFMT) alone | no estimate extracted | NR | No studies |
Number of women with adverse events ‐ abnormal vaginal bleeding Pessary plus PFMT vs pelvic floor muscle training (PFMT) alone | RR 2.18 [0.69, 6.91] | 1 study · 260 participants | Low Downgraded: imprecision |
Number of women with adverse events ‐ de novo voiding difficulty Pessary plus PFMT vs pelvic floor muscle training (PFMT) alone | RR 1.32 [0.54, 3.19] | 1 study · 189 participants | Low Downgraded: imprecision |