Cochrane · systematic review · CD005943

Progestogen for treating threatened miscarriage

Wahabi, HA, Fayed, AA, Esmaeil, SA, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library

Pregnancy and ChildbirthAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
3
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 33.3%Low 1 · 33.3%Moderate 1 · 33.3%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Progesterone compared to placebo or no treatment for treating threatened miscarriage

Population: women with threatened miscarriage
3 questions
OutcomeEffectEvidenceStatus / GRADE
Miscarriage
Progesterone vs placebo or no treatment
RR 0.64 [0.47, 0.87]7 studies · 696 participantsModerate
Downgraded: risk of bias
Preterm birth
Progesterone vs placebo or no treatment
RR 0.86 [0.52, 1.44]5 studies · 588 participantsLow
Downgraded: risk of bias, imprecision
Congential abnormalities
Progesterone vs placebo or no treatment
RR 0.7 [0.1, 4.82]2 studies · 337 participantsVery low
Downgraded: risk of bias, imprecision