Cochrane · systematic review · CD010167

Regular (ICSI) versus ultra‐high magnification (IMSI) sperm selection for assisted reproduction

Teixeira, DM, Miyague, AH, Barbosa, MAP, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library

Gynaecology and Fertility2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
4
No studies
1
Included studies
NR
No studies 1 · 20%Ungraded 0 · 0%Very low 4 · 80%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

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Comparison

Population: couples undergoing assisted reproduction treatment
5 questions
OutcomeEffectEvidenceStatus / GRADE
Live birth per allocated couple
RR 1.11 [0.89, 1.39]5 studies · 929 participantsVery low
Downgraded: risk of bias, imprecision
Miscarriage per allocated couple
RR 1.07 [0.78, 1.48]10 studies · 2297 participantsVery low
Downgraded: risk of bias, imprecision
Miscarriage per clinical pregnancy
RR 0.9 [0.68, 1.2]10 studies · 783 participantsVery low
Downgraded: risk of bias, imprecision
Clinical pregnancy per allocated couple
RR 1.23 [1.11, 1.37]13 studies · 2775 participantsVery low
Downgraded: risk of bias, inconsistency, publication bias
Congenital abnormalities per live birth
no estimate extractedNRNo studies