Cochrane · systematic review · CD010167
Regular (ICSI) versus ultra‐high magnification (IMSI) sperm selection for assisted reproduction
Teixeira, DM, Miyague, AH, Barbosa, MAP, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
4
No studies
1
Included studies
NR
No studies 1 · 20%Ungraded 0 · 0%Very low 4 · 80%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlyComparison
Population: couples undergoing assisted reproduction treatment
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Live birth per allocated couple | RR 1.11 [0.89, 1.39] | 5 studies · 929 participants | Very low Downgraded: risk of bias, imprecision |
Miscarriage per allocated couple | RR 1.07 [0.78, 1.48] | 10 studies · 2297 participants | Very low Downgraded: risk of bias, imprecision |
Miscarriage per clinical pregnancy | RR 0.9 [0.68, 1.2] | 10 studies · 783 participants | Very low Downgraded: risk of bias, imprecision |
Clinical pregnancy per allocated couple | RR 1.23 [1.11, 1.37] | 13 studies · 2775 participants | Very low Downgraded: risk of bias, inconsistency, publication bias |
Congenital abnormalities per live birth | no estimate extracted | NR | No studies |
Comparison
Population: couples undergoing assisted reproduction techniques
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Live birth per allocated couple | RR 1.14 [0.79, 1.64] | 1 study · 168 participants | Low Downgraded: risk of bias, imprecision, inconsistency, publication bias |
Clinical pregnancy per allocated couple | RR 1.29 [1.06, 1.55] | 9 studies · 2014 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, publication bias |
Miscarriage per clinical pregnancy | RR 0.82 [0.59, 1.14] | 6 studies · 552 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, publication bias |
Congenital abnormalities per clinical pregnancy | no estimate extracted | NR | No studies |