Findings

What do systematic reviews say?

573 questions · 608 findings · 115 reviews

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No studies found 136 · 22.4%GRADE not reported 54 · 8.9%Very low 166 · 27.3%Low 152 · 25%Moderate 75 · 12.3%High 25 · 4.1%

Computerised antenatal CTG vs traditional antenatal CTG (women at increased risk of complications)

Admission to neonatal special care unit or intensive care unit · Pregnant women with/without complications

The review found no eligible studies for this question.

1 finding from 1 review

Antenatal cardiotocography for fetal assessment 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Traditional antenatal CTG vs no antenatal CTG (women at increased risk of complication)

Admission to neonatal special care unit or intensive care unit · Pregnant women with/without complications

Traditional antenatal CTG showed no clear difference in admission to neonatal special care unit or intensive care unit compared with no antenatal CTG (women at increased risk of complication) (low certainty).

1 finding from 1 review

Antenatal cardiotocography for fetal assessment 2015 · Cochrane Headline outcomes only
RR 1.08 [0.84, 1.39]
2 studies · 883 participants
Low

Tranexamic acid vs placebo/no treatment

Serious maternal morbidity or death · pregnant women undergoing vaginal or caesarean birth who received TA for the prevention of postpartum haemorrhage

1 finding from 1 review

Tranexamic acid for preventing postpartum haemorrhage 2015 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 1511 participants
Low

Planned early birth vs expectant management

Significant maternal morbidity one or more of the following: significant postpartum haemorrhage requiring blood transfusion; maternal admission to intensive care unit; uterine rupture; hysterectomy · pregnant women with a term suspected compromised baby

Planned early delivery showed no clear difference in significant maternal morbidity one or more of the following:… compared with expectant management (low certainty).

1 finding from 1 review

Planned early delivery versus expectant management of the term suspected compromised baby for improving outcomes 2015 · Cochrane Headline outcomes only
RR 0.92 [0.38, 2.22]
1 study · 459 participants
Low

Intervention not reported

ICU ‐ intensive care unit · adults undergoing surgery requiring cardiac bypass

The review found no eligible studies for this question.

1 finding from 1 review

HMG CoA reductase inhibitors (statins) for preventing acute kidney injury after surgical procedures requiring cardiac… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Behavioural intervention vs control

Smoking cessation at time of surgery ‐ Intensive behavioural intervention (multiple contacts, initiated at least 4 weeks before surgery) · People awaiting surgery

Behavioural intervention probably leads to higher smoking cessation at time of surgery ‐ Intensive behavioural… compared with control (moderate certainty).

1 finding from 1 review

Interventions for preoperative smoking cessation 2014 · Cochrane Headline outcomes only
RR 10.76 [4.55, 25.46]
2 studies · 210 participants
Moderate

Behavioural intervention vs control

Postoperative morbidity: Any complication ‐ Intensive intervention · People awaiting surgery

Behavioural intervention probably leads to lower postoperative morbidity: Any complication ‐ Intensive intervention compared with control (moderate certainty).

1 finding from 1 review

Interventions for preoperative smoking cessation 2014 · Cochrane Headline outcomes only
RR 0.42 [0.27, 0.65]
2 studies · 210 participants
Moderate

Antibiotics vs placebo

Mortality and morbidity prior to discharge (Neonatal intensive care admissions) · Women with meconium‐stained amniotic fluid in labour, gestational age more than 24 weeks

Antibiotic showed no clear difference in mortality and morbidity prior to discharge (Neonatal intensive care… compared with placebo (low certainty).

1 finding from 1 review

Antibiotics for meconium‐stained amniotic fluid in labour for preventing maternal and neonatal infections 2014 · Cochrane Headline outcomes only
RR 0.83 [0.39, 1.78]
1 study · 120 participants
Low

Antibiotics vs placebo

Duration of admission to neonatal intensive care unit · Women with meconium‐stained amniotic fluid in labour, gestational age more than 24 weeks

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics for meconium‐stained amniotic fluid in labour for preventing maternal and neonatal infections 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Continuous outcomes automated vs non‐automated weaning

Intensive care unit length of stay (based on type of control arm): predominantly protocolized control strategy · patients with weaning time in invasively ventilated critically ill adults

1 finding from 1 review

Automated weaning and SBT systems versus non‐automated weaning strategies for weaning time in invasively ventilated… 2014 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 337 participants
Low

Continuous outcomes automated vs non‐automated weaning

Intensive care unit length of stay (based on type of control arm): predominantly non‐protocolized control strategy · patients with weaning time in invasively ventilated critically ill adults

1 finding from 1 review

Automated weaning and SBT systems versus non‐automated weaning strategies for weaning time in invasively ventilated… 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 162 participants
Moderate

Combination of anticholinergics + beta2‐agonists vs B2‐agonists alone

Incidence of admissions to the ICU · children hospitalised with an acute asthma exacerbation

1 finding from 1 review

Inhaled anticholinergics and short‐acting beta₂‐agonists versus short‐acting beta2‐agonists alone for children with… 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 210 participants
Moderate

Intervention not reported

Intensive care unit (ICU) admissions · adults with acute asthma

The intervention showed no clear difference in intensive care unit (ICU) admissions (low certainty).

1 finding from 1 review

Intravenous magnesium sulfate for treating adults with acute asthma in the emergency department 2014 · Cochrane Headline outcomes only
OR 2.03 [0.7, 5.89]
1 study · 752 participants
Low

Monitoring of contractions with internal tocodynamometry vs external tocodynamometry

Admission to neonatal intensive care unit

Monitoring of contractions with internal tocodynamometry showed no clear difference in admission to neonatal intensive care compared with external tocodynamometry (moderate certainty).

1 finding from 1 review

Internal versus external tocodynamometry during induced or augmented labour 2013 · Cochrane Headline outcomes only
RR 0.34 [0.07, 1.67]
2 studies · 489 participants
Moderate

Fibrinogen concentrate vs any comparator

ICU length of stay (general intensive care patients) · bleeding patients or at risk of severe bleeding

1 finding from 1 review

Fibrinogen concentrate in bleeding patients 2013 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 112 participants
Very low

Intervention not reported

Length of stay on the intensive care unit (days) · Adult patients with SIRS or sepsis

1 finding from 1 review

N‐acetylcysteine for sepsis and systemic inflammatory response in adults 2012 · Cochrane Headline outcomes only
no estimate extracted
19 studies · 1309 participants
Moderate

Postoperative feeding via nasojejunal tube vs no postoperative parental nutrition (conventional intravenous electrolyte solution)

Intensive care unit length of stay after liver transplantation [hours] · adult patients after liver transplantation.

1 finding from 1 review

Nutritional interventions for liver‐transplanted patients 2012 · Cochrane Headline outcomes only
no estimate extracted
1 study · 31 participants
Very low

Enteral nutrition via nasojejunal tube plus intravenous glutamine‐dipeptide supplementation vs parenteral nutrition

Intensive care unit length of stay after liver transplantation [days] (ITT) · adult patients after liver transplantation.

1 finding from 1 review

Nutritional interventions for liver‐transplanted patients 2012 · Cochrane Headline outcomes only
no estimate extracted
1 study · 30 participants
Very low

Parenteral nutrition plus branched‐chain‐amino‐acid‐enriched formula vs standard isotonic intravenous glucose solution

Intensive care unit length of stay after liver transplantation [days] (ITT) · adult patients after liver transplantation.

1 finding from 1 review

Nutritional interventions for liver‐transplanted patients 2012 · Cochrane Headline outcomes only
no estimate extracted
1 study · 20 participants
Low

Parenteral nutrition with omega‐3 fish oil vs parenteral nutrition

Intensive care unit length of stay after liver transplantation [days] (ITT) · adult patients after liver transplantation.

1 finding from 1 review

Nutritional interventions for liver‐transplanted patients 2012 · Cochrane Headline outcomes only
no estimate extracted
1 study · 36 participants
Very low