Cochrane · systematic review · CD009433

Planned early delivery versus expectant management of the term suspected compromised baby for improving outcomes

Bond, DM, Gordon, A, Hyett, J, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library

Pregnancy and ChildbirthAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 14.3%Low 5 · 71.4%Moderate 1 · 14.3%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Planned early delivery compared with expectant management for improving outcomes of the term suspected compromised baby

Population: pregnant women with a term suspected compromised baby
7 questions
OutcomeEffectEvidenceStatus / GRADE
Perinatal mortality (stillbirth ‐ death of fetus prior to birth; neonatal death ‐ death within the first 28 days of birth; or infant death ‐ death after the first 28 days)
Planned early delivery vs expectant management
no estimate extracted1 study · 459 participantsModerate
Major neonatal morbidity one or more of the following: hypoxic ischaemic encephalopathy (HIE) ‐ grade II or III, necrotising enterocolitis (NEC), need for ongoing ventilation, meconium aspiration syndrome, seizures, need for therapeutic hypothermia
Planned early delivery vs expectant management
RR 0.15 [0.01, 2.81]1 study · 459 participantsLow
Downgraded: imprecision
Neurodevelopmental disability/impairment CBCL, Ages and Stages Questionnaire
Planned early delivery vs expectant management
RR 2.04 [0.62, 6.69]1 study · 459 participantsLow
Downgraded: imprecision
Maternal mortality
Planned early delivery vs expectant management
RR 3.07 [0.13, 74.87]1 study · 459 participantsLow
Downgraded: imprecision
Significant maternal morbidity one or more of the following: significant postpartum haemorrhage requiring blood transfusion; maternal admission to intensive care unit; uterine rupture; hysterectomy
Planned early delivery vs expectant management
RR 0.92 [0.38, 2.22]1 study · 459 participantsLow
Downgraded: imprecision
Admission to NICU
Planned early delivery vs expectant management
RR 0.88 [0.35, 2.23]3 studies · 545 participantsVery low
Downgraded: imprecision
Caesarean section
Planned early delivery vs expectant management
RR 1.02 [0.65, 1.59]3 studies · 546 participantsLow
Downgraded: imprecision