Cochrane · systematic review · CD007772
Antibiotics for meconium‐stained amniotic fluid in labour for preventing maternal and neonatal infections
Siriwachirachai, T, Sangkomkamhang, US, Lumbiganon, P, et al. · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library
Pregnancy and ChildbirthAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
4
No studies
2
Included studies
NR
No studies 2 · 33.3%Ungraded 0 · 0%Very low 0 · 0%Low 3 · 50%Moderate 1 · 16.7%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Antibiotic versus placebo for meconium‐stained amniotic fluid in labour for preventing maternal and neonatal infections
Population: Women with meconium‐stained amniotic fluid in labour, gestational age more than 24 weeks
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Neonatal sepsis Antibiotic vs placebo | RR 1 [0.21, 4.76] | 1 study · 120 participants | Low Downgraded: imprecision |
Chorioamnionitis Antibiotic vs placebo | RR 0.36 [0.21, 0.62] | 2 studies · 362 participants | Moderate |
Postpartum endometritis Antibiotic vs placebo | RR 0.5 [0.18, 1.38] | 1 study · 120 participants | Low Downgraded: imprecision |
Mortality and morbidity prior to discharge (Neonatal intensive care admissions) Antibiotic vs placebo | RR 0.83 [0.39, 1.78] | 1 study · 120 participants | Low Downgraded: imprecision |
Side effects of treatment Antibiotic vs placebo | no estimate extracted | NR | No studies |
Duration of admission to neonatal intensive care unit Antibiotic vs placebo | no estimate extracted | NR | No studies |